blebbistatin-954 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the blebbistatin-954 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ADRBK2 adrenergic, beta, receptor kinase 2
AKAP13 A kinase (PRKA) anchor protein 13
AKAP17A A kinase (PRKA) anchor protein 17A
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ATF3 activating transcription factor 3
ATXN1 ataxin 1
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BIK BCL2-interacting killer (apoptosis-inducing)
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CD24 CD24 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CENPO centromere protein O
CFLAR CASP8 and FADD-like apoptosis regulator
CLUAP1 clusterin associated protein 1
CRYBG3 beta-gamma crystallin domain containing 3
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVA1B eva-1 homolog B (C. elegans)
FAM49B family with sequence similarity 49, member B
FANCA Fanconi anemia, complementation group A
FGD1 FYVE, RhoGEF and PH domain containing 1
FMOD fibromodulin
FURIN furin (paired basic amino acid cleaving enzyme)
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GLIPR1 GLI pathogenesis-related 1
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMGXB3 HMG box domain containing 3
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INHBE inhibin, beta E
IRAK4 interleukin-1 receptor-associated kinase 4
JUN jun proto-oncogene
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KIAA0319L KIAA0319-like
KLHL22 kelch-like family member 22
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LARP7 La ribonucleoprotein domain family, member 7
LPIN1 lipin 1
LRP2 low density lipoprotein receptor-related protein 2
LTBP4 latent transforming growth factor beta binding protein 4
MBD1 methyl-CpG binding domain protein 1
MCM3AP minichromosome maintenance complex component 3 associated protein
METTL5 methyltransferase like 5
MPI mannose phosphate isomerase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MTERF4 mitochondrial transcription termination factor 4
MVP major vault protein
MYO9B myosin IXB
MZT2B mitotic spindle organizing protein 2B
NDRG2 NDRG family member 2
NEB nebulin
NFS1 NFS1 cysteine desulfurase
NGLY1 N-glycanase 1
OASL 2'-5'-oligoadenylate synthetase-like
PAPOLA poly(A) polymerase alpha
PAQR6 progestin and adipoQ receptor family member VI
PER1 period circadian clock 1
PEX26 peroxisomal biogenesis factor 26
PGR progesterone receptor
PHF14 PHD finger protein 14
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRLR prolactin receptor
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PVT1 Pvt1 oncogene (non-protein coding)
RAB32 RAB32, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RPGRIP1L RPGRIP1-like
SIK2 salt-inducible kinase 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMTN smoothelin
SPINK5 serine peptidase inhibitor, Kazal type 5
SREBF2 sterol regulatory element binding transcription factor 2
STRN striatin, calmodulin binding protein
SUN2 Sad1 and UNC84 domain containing 2
SYT12 synaptotagmin XII
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
THBD thrombomodulin
THRAP3 thyroid hormone receptor associated protein 3
UBOX5 U-box domain containing 5
USP36 ubiquitin specific peptidase 36
WAS Wiskott-Aldrich syndrome
YY2 YY2 transcription factor
ZFX zinc finger protein, X-linked
ZNF79 zinc finger protein 79
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2B activin A receptor, type IIB
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALDOC aldolase C, fructose-bisphosphate
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
ARMC6 armadillo repeat containing 6
ASB9 ankyrin repeat and SOCS box containing 9
ATAD5 ATPase family, AAA domain containing 5
ATG9A autophagy related 9A
BBC3 BCL2 binding component 3
BCL9 B-cell CLL/lymphoma 9
BCORL1 BCL6 corepressor-like 1
BEX4 brain expressed, X-linked 4
BOLA1 bolA family member 1
BPGM 2,3-bisphosphoglycerate mutase
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD2 BTB (POZ) domain containing 2
C21ORF91 chromosome 21 open reading frame 91
C22ORF29 chromosome 22 open reading frame 29
CCDC88C coiled-coil domain containing 88C
CCNE1 cyclin E1
CCNT1 cyclin T1
CD151 CD151 molecule (Raph blood group)
CENPJ centromere protein J
CHPF chondroitin polymerizing factor
CNPY3 canopy FGF signaling regulator 3
COG4 component of oligomeric golgi complex 4
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHRS3 dehydrogenase/reductase (SDR family) member 3
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNAL4 dynein, axonemal, light chain 4
EFHD2 EF-hand domain family, member D2
EHD3 EH-domain containing 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FMO4 flavin containing monooxygenase 4
FOXD1 forkhead box D1
FOXRED2 FAD-dependent oxidoreductase domain containing 2
HIST1H2AG histone cluster 1, H2ag
HIST1H2BI histone cluster 1, H2bi
HPSE heparanase
HSPA1L heat shock 70kDa protein 1-like
IRF7 interferon regulatory factor 7
KDM5C lysine (K)-specific demethylase 5C
KIAA0232 KIAA0232
LRP3 low density lipoprotein receptor-related protein 3
LY6G5C lymphocyte antigen 6 complex, locus G5C
LYPD1 LY6/PLAUR domain containing 1
MAP6D1 MAP6 domain containing 1
MFSD12 major facilitator superfamily domain containing 12
MIS18BP1 MIS18 binding protein 1
MTA2 metastasis associated 1 family, member 2
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NCAPH non-SMC condensin I complex, subunit H
NT5E 5'-nucleotidase, ecto (CD73)
ORAI3 ORAI calcium release-activated calcium modulator 3
PCDHB3 protocadherin beta 3
PHC2 polyhomeotic homolog 2 (Drosophila)
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
PP14571 uncharacterized LOC100130449
PXMP4 peroxisomal membrane protein 4, 24kDa
QTRT1 queuine tRNA-ribosyltransferase 1
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RIBC2 RIB43A domain with coiled-coils 2
RIPK4 receptor-interacting serine-threonine kinase 4
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SETD3 SET domain containing 3
SF3A2 splicing factor 3a, subunit 2, 66kDa
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SNUPN snurportin 1
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic)
TEX264 testis expressed 264
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TMEM254 transmembrane protein 254
TMEM260 transmembrane protein 260
TMPRSS3 transmembrane protease, serine 3
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNRC6B trinucleotide repeat containing 6B
TNS3 tensin 3
TRAPPC6A trafficking protein particle complex 6A
TRIM5 tripartite motif containing 5
TRMT61B tRNA methyltransferase 61B
TTF2 transcription termination factor, RNA polymerase II
TUBA3D tubulin, alpha 3d
URGCP upregulator of cell proliferation
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR46 WD repeat domain 46
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZNF226 zinc finger protein 226
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574
ZNF611 zinc finger protein 611