bladder carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A urinary bladder cancer that has_material_basis_in abnormally proliferating cells derives_from epithelial cells. (Human Disease Ontology, DOID_4007)
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Genes

337 genes co-occuring with the disease bladder carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TP53 tumor protein p53 1.45001
ZNF135 zinc finger protein 135 1.32105
UPK2 uroplakin 2 1.20656
UCA1 urothelial cancer associated 1 (non-protein coding) 1.20266
KRT20 keratin 20, type I 1.18023
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 1.16606
FGFR3 fibroblast growth factor receptor 3 1.16008
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 1.12572
HRAS Harvey rat sarcoma viral oncogene homolog 1.11814
BLCAP bladder cancer associated protein 1.09503
UPK3A uroplakin 3A 1.04083
SPRR2G small proline-rich protein 2G 0.952021
CNTN2 contactin 2 (axonal) 0.946603
ERBB2 erb-b2 receptor tyrosine kinase 2 0.930414
C9ORF9 chromosome 9 open reading frame 9 0.919261
HEPACAM hepatic and glial cell adhesion molecule 0.899924
UPK1B uroplakin 1B 0.855677
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.81059
BIRC5 baculoviral IAP repeat containing 5 0.803205
IFNA21 interferon, alpha 21 0.769618
FAM195A family with sequence similarity 195, member A 0.769618
IL2 interleukin 2 0.765127
NEK7 NIMA-related kinase 7 0.756971
IFNA17 interferon, alpha 17 0.745985
CDKN2A cyclin-dependent kinase inhibitor 2A 0.738676
SMTN smoothelin 0.732596
MUC7 mucin 7, secreted 0.730166
CDX2 caudal type homeobox 2 0.713601
LITAF lipopolysaccharide-induced TNF factor 0.711989
EGFR epidermal growth factor receptor 0.711183
KRT7 keratin 7, type II 0.70434
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase 0.691094
FGF1 fibroblast growth factor 1 (acidic) 0.686291
TERT telomerase reverse transcriptase 0.681495
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.676706
STEAP2 STEAP family member 2, metalloreductase 0.675909
FGF2 fibroblast growth factor 2 (basic) 0.672722
ANG angiogenin, ribonuclease, RNase A family, 5 0.672722
CCND1 cyclin D1 0.670333
MMP2 matrix metallopeptidase 2 0.656837
RALB v-ral simian leukemia viral oncogene homolog B 0.640645
LAMC3 laminin, gamma 3 0.63042
LZTS2 leucine zipper, putative tumor suppressor 2 0.629635
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.629242
GATA3 GATA binding protein 3 0.628065
MAGEA8 melanoma antigen family A8 0.624143
KLK3 kallikrein-related peptidase 3 0.624143
RNF20 ring finger protein 20, E3 ubiquitin protein ligase 0.615138
GOLGA5 golgin A5 0.614356
HBA1 hemoglobin, alpha 1 0.614356
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.613183
GBP5 guanylate binding protein 5 0.610448
IFNA2 interferon, alpha 2 0.610057
MKI67 marker of proliferation Ki-67 0.607714
HBA2 hemoglobin, alpha 2 0.60342
PCDH10 protocadherin 10 0.597571
IFNA6 interferon, alpha 6 0.585497
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.578883
FN1 fibronectin 1 0.569163
HMGN5 high mobility group nucleosome binding domain 5 0.566054
IGF2 insulin-like growth factor 2 0.557509
UBE2M ubiquitin-conjugating enzyme E2M 0.543155
HPD 4-hydroxyphenylpyruvate dioxygenase 0.535796
PDCD6IP programmed cell death 6 interacting protein 0.533475
ACPP acid phosphatase, prostate 0.530768
ANKRD6 ankyrin repeat domain 6 0.528449
GSTP1 glutathione S-transferase pi 1 0.526132
FASLG Fas ligand (TNF superfamily, member 6) 0.520346
MUC1 mucin 1, cell surface associated 0.514571
DAPK1 death-associated protein kinase 1 0.504207
PDPN podoplanin 0.504207
MMP9 matrix metallopeptidase 9 0.493885
S100A7 S100 calcium binding protein A7 0.493885
CAPN9 calpain 9 0.493885
AGGF1 angiogenic factor with G patch and FHA domains 1 0.491597
CDY2A chromodomain protein, Y-linked, 2A 0.491215
CD44 CD44 molecule (Indian blood group) 0.488549
PCDH17 protocadherin 17 0.479427
RSF1 remodeling and spacing factor 1 0.479427
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.476014
RFXANK regulatory factor X-associated ankyrin-containing protein 0.474119
RB1 retinoblastoma 1 0.47374
PTEN phosphatase and tensin homolog 0.471468
ZNF77 zinc finger protein 77 0.462772
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.460883
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.458996
PCNA proliferating cell nuclear antigen 0.458996
CDH13 cadherin 13 0.457864
EDIL3 EGF-like repeats and discoidin I-like domains 3 0.457487
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.456355
TPBG trophoblast glycoprotein 0.438658
ANGPTL1 angiopoietin-like 1 0.436402
STEAP4 STEAP family member 4 0.435275
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.433021
GBP2 guanylate binding protein 2, interferon-inducible 0.42664
KRT19 keratin 19, type I 0.421016
TIMP2 TIMP metallopeptidase inhibitor 2 0.419892
NTNG2 netrin G2 0.418394
ACLY ATP citrate lyase 0.416521
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1 0.415773
GALNT1 polypeptide N-acetylgalactosaminyltransferase 1 0.413901
KRT18 keratin 18, type I 0.406798
NMUR2 neuromedin U receptor 2 0.405678
RTKN rhotekin 0.404557
CD6 CD6 molecule 0.402318
SOX4 SRY (sex determining region Y)-box 4 0.401945
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.398589
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.398216
TYMP thymidine phosphorylase 0.397471
GSTM5 glutathione S-transferase mu 5 0.396725
FGF13 fibroblast growth factor 13 0.393746
HNRNPM heterogeneous nuclear ribonucleoprotein M 0.390397
ZNF384 zinc finger protein 384 0.390397
MAGEA12 melanoma antigen family A12 0.390397
CERS2 ceramide synthase 2 0.387423
GSTA3 glutathione S-transferase alpha 3 0.387423
GSTA2 glutathione S-transferase alpha 2 0.386308
GSTA4 glutathione S-transferase alpha 4 0.385193
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.38111
GSTA1 glutathione S-transferase alpha 1 0.379256
BSG basigin (Ok blood group) 0.377402
RPL3 ribosomal protein L3 0.37555
PMF1 polyamine-modulated factor 1 0.370368
GSTM4 glutathione S-transferase mu 4 0.369997
CD4 CD4 molecule 0.369628
KRT8 keratin 8, type II 0.368518
ANLN anillin, actin binding protein 0.368518
SART3 squamous cell carcinoma antigen recognized by T cells 3 0.368149
KDM5B lysine (K)-specific demethylase 5B 0.368149
BIRC7 baculoviral IAP repeat containing 7 0.36704
GSTM1 glutathione S-transferase mu 1 0.362239
STEAP3 STEAP family member 3, metalloreductase 0.361133
PIWIL2 piwi-like RNA-mediated gene silencing 2 0.360026
FHIT fragile histidine triad 0.359657
THBD thrombomodulin 0.359289
SRL sarcalumenin 0.355604
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.354499
CA9 carbonic anhydrase IX 0.354131
PARP1 poly (ADP-ribose) polymerase 1 0.354131
IFNA1 interferon, alpha 1 0.346042
GSTTP1 glutathione S-transferase theta pseudogene 1 0.345308
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 0.345308
GSTT1 glutathione S-transferase theta 1 0.345308
DMBT1 deleted in malignant brain tumors 1 0.343106
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.337975
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.337242
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.335778
BAX BCL2-associated X protein 0.334681
CSF1 colony stimulating factor 1 (macrophage) 0.334315
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.333218
SFN stratifin 0.332121
SLC45A3 solute carrier family 45, member 3 0.328105
CDY1B chromodomain protein, Y-linked, 1B 0.324823
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.324094
LZTS1 leucine zipper, putative tumor suppressor 1 0.318272
SYP synaptophysin 0.315729
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.31464
FRK fyn-related Src family tyrosine kinase 0.311739
AMACR alpha-methylacyl-CoA racemase 0.310652
FOXQ1 forkhead box Q1 0.308842
HSPH1 heat shock 105kDa/110kDa protein 1 0.308118
EFNA3 ephrin-A3 0.30342
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.300173
PRDM6 PR domain containing 6 0.299812
FADD Fas (TNFRSF6)-associated via death domain 0.299812
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.295851
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 0.295492
STPG1 sperm-tail PG-rich repeat containing 1 0.294053
VEGFC vascular endothelial growth factor C 0.289386
FGF17 fibroblast growth factor 17 0.288668
CLU clusterin 0.287952
ZC2HC1A zinc finger, C2HC-type containing 1A 0.284728
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 0.284728
CPM carboxypeptidase M 0.282225
FGF6 fibroblast growth factor 6 0.280439
PSCA prostate stem cell antigen 0.280439
DLK1 delta-like 1 homolog (Drosophila) 0.274376
GEMIN4 gem (nuclear organelle) associated protein 4 0.273664
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.271174
TGFB1 transforming growth factor, beta 1 0.270819
PPP1R13L protein phosphatase 1, regulatory subunit 13 like 0.270464
GJA1 gap junction protein, alpha 1, 43kDa 0.270464
ADCY4 adenylate cyclase 4 0.269753
LDHB lactate dehydrogenase B 0.268332
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.26514
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.264077
FGF4 fibroblast growth factor 4 0.26266
AHRR aryl-hydrocarbon receptor repressor 0.261952
ASXL1 additional sex combs like transcriptional regulator 1 0.260538
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.260538
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.257711
STEAP1 six transmembrane epithelial antigen of the prostate 1 0.257358
ENO2 enolase 2 (gamma, neuronal) 0.255946
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.254536
LACTB lactamase, beta 0.253479
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.253127
ADCY7 adenylate cyclase 7 0.250311
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.250311
PLAU plasminogen activator, urokinase 0.249608
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 0.249608
EIF3A eukaryotic translation initiation factor 3, subunit A 0.249257
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.248203
CTSD cathepsin D 0.246448
TPM4 tropomyosin 4 0.246098
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.245747
EDNRB endothelin receptor type B 0.245747
HOXA13 homeobox A13 0.244696
DAB2IP DAB2 interacting protein 0.242595
NID2 nidogen 2 (osteonidogen) 0.239799
MFGE8 milk fat globule-EGF factor 8 protein 0.235964
OPCML opioid binding protein/cell adhesion molecule-like 0.235616
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 0.230063
FGF8 fibroblast growth factor 8 (androgen-induced) 0.227297
PROK1 prokineticin 1 0.226952
PDZD2 PDZ domain containing 2 0.224196
CD82 CD82 molecule 0.223509
CD40LG CD40 ligand 0.221793
VEGFA vascular endothelial growth factor A 0.219398
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.214297
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.211934
GBP1 guanylate binding protein 1, interferon-inducible 0.207245
GPR17 G protein-coupled receptor 17 0.20658
IL3 interleukin 3 0.205254
POLB polymerase (DNA directed), beta 0.204923
ADCY1 adenylate cyclase 1 (brain) 0.204923
PDCD5 programmed cell death 5 0.204593
CD1A CD1a molecule 0.203933
ADCY3 adenylate cyclase 3 0.203604
IFNB1 interferon, beta 1, fibroblast 0.202946
MXI1 MAX interactor 1, dimerization protein 0.201962
HMBS hydroxymethylbilane synthase 0.200656
SRSF1 serine/arginine-rich splicing factor 1 0.200656
CCNE1 cyclin E1 0.198386
NTM neurotrimin 0.197099
GSR glutathione reductase 0.195183
CHGA chromogranin A 0.194232
TSPO translocator protein (18kDa) 0.193915
MUC2 mucin 2, oligomeric mucus/gel-forming 0.1936
CD34 CD34 molecule 0.192657
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.192031
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.191719
CD27 CD27 molecule 0.191408
TGFBR1 transforming growth factor, beta receptor 1 0.189859
HSPA4 heat shock 70kDa protein 4 0.185612
DNTT DNA nucleotidylexotransferase 0.185612
TBP TATA box binding protein 0.183835
ADCY10 adenylate cyclase 10 (soluble) 0.183835
FGFR2 fibroblast growth factor receptor 2 0.183835
ACTG1 actin gamma 1 0.182666
MCM7 minichromosome maintenance complex component 7 0.181798
ADAM28 ADAM metallopeptidase domain 28 0.181798
DSP desmoplakin 0.18151
AQP7 aquaporin 7 0.18151
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.181222
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.181222
FGF5 fibroblast growth factor 5 0.180652
THBS1 thrombospondin 1 0.17952
CNN1 calponin 1, basic, smooth muscle 0.179239
ILK integrin-linked kinase 0.178126
HAS3 hyaluronan synthase 3 0.170789
CDC25C cell division cycle 25C 0.170544
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.169812
ADCY9 adenylate cyclase 9 0.168381
MDK midkine (neurite growth-promoting factor 2) 0.163729
ODC1 ornithine decarboxylase 1 0.163111
ADCY6 adenylate cyclase 6 0.162505
B3GAT1 beta-1,3-glucuronyltransferase 1 0.161912
ERCC2 excision repair cross-complementation group 2 0.161716
CDA cytidine deaminase 0.161523
ADCY5 adenylate cyclase 5 0.160948
LYZ lysozyme 0.160203
PLG plasminogen 0.160203
CTAG2 cancer/testis antigen 2 0.159302
POLL polymerase (DNA directed), lambda 0.158266
NMS neuromedin S 0.157929
KIF11 kinesin family member 11 0.143124
CUL1 cullin 1 0.142819
SKP1 S-phase kinase-associated protein 1 0.139941
SDF4 stromal cell derived factor 4 0.138967
CCNB1 cyclin B1 0.13771
MSH3 mutS homolog 3 0.137503
TCHH trichohyalin 0.137431
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.135076
CDX1 caudal type homeobox 1 0.134441
NAPSA napsin A aspartic peptidase 0.132824
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.130787
VIL1 villin 1 0.13039
S100P S100 calcium binding protein P 0.130279
JAG1 jagged 1 0.129629
GPC3 glypican 3 0.129091
NOTCH1 notch 1 0.128459
DLL1 delta-like 1 (Drosophila) 0.126797
EML4 echinoderm microtubule associated protein like 4 0.125952
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.125778
FLOT1 flotillin 1 0.125529
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.124341
HOXA5 homeobox A5 0.124126
ESAM endothelial cell adhesion molecule 0.124048
PLK2 polo-like kinase 2 0.123929
SEPT4 septin 4 0.123831
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.123015
IGFBP3 insulin-like growth factor binding protein 3 0.122268
IL23R interleukin 23 receptor 0.12216
FGF3 fibroblast growth factor 3 0.121604
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.121559
MAGEA4 melanoma antigen family A4 0.121446
EPAS1 endothelial PAS domain protein 1 0.121379
SPAG9 sperm associated antigen 9 0.120753
DHDH dihydrodiol dehydrogenase (dimeric) 0.119057
HAS2 hyaluronan synthase 2 0.118277
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0.117115
POU5F1 POU class 5 homeobox 1 0.115388
MAGEA1 melanoma antigen family A1 0.113892
WARS tryptophanyl-tRNA synthetase 0.112574
WWOX WW domain containing oxidoreductase 0.112541
GRP gastrin-releasing peptide 0.11171
IGFBP5 insulin-like growth factor binding protein 5 0.110926
FSCN3 fascin actin-bundling protein 3, testicular 0.10901
PTS 6-pyruvoyltetrahydropterin synthase 0.106715
KRT5 keratin 5, type II 0.106715
P4HB prolyl 4-hydroxylase, beta polypeptide 0.106559
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.10652
FSCN2 fascin actin-bundling protein 2, retinal 0.106364
TNF tumor necrosis factor 0.105736
NTN1 netrin 1 0.104896
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.104448
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 0.103122
MMP10 matrix metallopeptidase 10 0.102406
GLI2 GLI family zinc finger 2 0.101587
GCH1 GTP cyclohydrolase 1 0.100977
HAS1 hyaluronan synthase 1 0.100624
GP5 glycoprotein V (platelet) 0.100051
CFB complement factor B 0.097121
BCL2 B-cell CLL/lymphoma 2 0.096509
PRDX5 peroxiredoxin 5 0.096462
PLK1 polo-like kinase 1 0.095987
ANXA1 annexin A1 0.095698