bisacodyl-3297 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bisacodyl-3297 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AKAP8L A kinase (PRKA) anchor protein 8-like
AKAP9 A kinase (PRKA) anchor protein 9
ARNT aryl hydrocarbon receptor nuclear translocator
ATF3 activating transcription factor 3
AVPI1 arginine vasopressin-induced 1
BAAT bile acid CoA:amino acid N-acyltransferase
BCL6 B-cell CLL/lymphoma 6
CCDC186 coiled-coil domain containing 186
CCDC88C coiled-coil domain containing 88C
CCNT2 cyclin T2
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
COL3A1 collagen, type III, alpha 1
CTTN cortactin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EDRF1 erythroid differentiation regulatory factor 1
EED embryonic ectoderm development
EGR1 early growth response 1
ETNK1 ethanolamine kinase 1
EWSR1 EWS RNA-binding protein 1
FAM46A family with sequence similarity 46, member A
FLCN folliculin
GEM GTP binding protein overexpressed in skeletal muscle
GLS glutaminase
GOLGA4 golgin A4
GPATCH3 G patch domain containing 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBP1 HMG-box transcription factor 1
HIC2 hypermethylated in cancer 2
HIST1H4C histone cluster 1, H4c
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXB2 homeobox B2
HOXC13 homeobox C13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
INSL4 insulin-like 4 (placenta)
IP6K2 inositol hexakisphosphate kinase 2
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL24 kelch-like family member 24
LCT lactase
LDLR low density lipoprotein receptor
LPP LIM domain containing preferred translocation partner in lipoma
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MEF2D myocyte enhancer factor 2D
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
N4BP2L2 NEDD4 binding protein 2-like 2
NACA nascent polypeptide-associated complex alpha subunit
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFYA nuclear transcription factor Y, alpha
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5M 5',3'-nucleotidase, mitochondrial
OVOL1 ovo-like zinc finger 1
PCDH9 protocadherin 9
PCNX pecanex homolog (Drosophila)
PDS5B PDS5 cohesin associated factor B
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PUM1 pumilio RNA-binding family member 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBM15 RNA binding motif protein 15
RBM48 RNA binding motif protein 48
RBM5 RNA binding motif protein 5
RSRC2 arginine/serine-rich coiled-coil 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC38A2 solute carrier family 38, member 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SOX9 SRY (sex determining region Y)-box 9
SPRY4 sprouty homolog 4 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRSF5 serine/arginine-rich splicing factor 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF25 transcription factor 25 (basic helix-loop-helix)
TRA2A transformer 2 alpha homolog (Drosophila)
TXNIP thioredoxin interacting protein
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
YTHDC1 YTH domain containing 1
ZBTB40 zinc finger and BTB domain containing 40
ZFAND6 zinc finger, AN1-type domain 6
ZFX zinc finger protein, X-linked
ZMYM2 zinc finger, MYM-type 2
ZNF335 zinc finger protein 335
ZNF451 zinc finger protein 451

decreased expression

Symbol Name
ALAS1 5'-aminolevulinate synthase 1
ANKRD46 ankyrin repeat domain 46
ARMCX1 armadillo repeat containing, X-linked 1
ASB13 ankyrin repeat and SOCS box containing 13
ASTE1 asteroid homolog 1 (Drosophila)
BBS10 Bardet-Biedl syndrome 10
C14ORF169 chromosome 14 open reading frame 169
C17ORF80 chromosome 17 open reading frame 80
C5ORF45 chromosome 5 open reading frame 45
C7ORF49 chromosome 7 open reading frame 49
CBR3 carbonyl reductase 3
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOLK dolichol kinase
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFTUD1 elongation factor Tu GTP binding domain containing 1
FADD Fas (TNFRSF6)-associated via death domain
FANCF Fanconi anemia, complementation group F
FJX1 four jointed box 1 (Drosophila)
FZD4 frizzled class receptor 4
GCA grancalcin, EF-hand calcium binding protein
GEMIN6 gem (nuclear organelle) associated protein 6
GLRX2 glutaredoxin 2
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HPS5 Hermansky-Pudlak syndrome 5
HPS6 Hermansky-Pudlak syndrome 6
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
KIAA0125 KIAA0125
KRCC1 lysine-rich coiled-coil 1
LOC100287590 uncharacterized LOC100287590
LOC642236 FSHD region gene 1 pseudogene
MKKS McKusick-Kaufman syndrome
MORC2 MORC family CW-type zinc finger 2
MRPS31 mitochondrial ribosomal protein S31
MXD3 MAX dimerization protein 3
NELFE negative elongation factor complex member E
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALB2 partner and localizer of BRCA2
PCF11 PCF11 cleavage and polyadenylation factor subunit
PEX11B peroxisomal biogenesis factor 11 beta
PEX12 peroxisomal biogenesis factor 12
POLR3B polymerase (RNA) III (DNA directed) polypeptide B
PRR15L proline rich 15-like
PRR3 proline rich 3
RANBP6 RAN binding protein 6
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RPP40 ribonuclease P/MRP 40kDa subunit
RPUSD2 RNA pseudouridylate synthase domain containing 2
RSAD1 radical S-adenosyl methionine domain containing 1
S100PBP S100P binding protein
SACS sacsin molecular chaperone
SCO2 SCO2 cytochrome c oxidase assembly protein
SEPHS2 selenophosphate synthetase 2
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SPATA7 spermatogenesis associated 7
SPC25 SPC25, NDC80 kinetochore complex component
SRGAP2 SLIT-ROBO Rho GTPase activating protein 2
SUOX sulfite oxidase
TBC1D31 TBC1 domain family, member 31
TFB1M transcription factor B1, mitochondrial
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRAPPC13 trafficking protein particle complex 13
TRIM45 tripartite motif containing 45
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMT61B tRNA methyltransferase 61B
TTC4 tetratricopeptide repeat domain 4
VANGL1 VANGL planar cell polarity protein 1
WDR3 WD repeat domain 3
WDR5B WD repeat domain 5B
XPC xeroderma pigmentosum, complementation group C
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZC3H4 zinc finger CCCH-type containing 4
ZFP30 ZFP30 zinc finger protein
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF189 zinc finger protein 189
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF248 zinc finger protein 248
ZNF302 zinc finger protein 302
ZNF510 zinc finger protein 510
ZNF668 zinc finger protein 668
ZNF7 zinc finger protein 7
ZSCAN9 zinc finger and SCAN domain containing 9
ZW10 zw10 kinetochore protein