bipolar disorder Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A mood disorder that involves alternating periods of mania and depression. (Human Disease Ontology, DOID_3312)
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Genes

126 genes associated with the disease bipolar disorder in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.894262
HIST1H2BL histone cluster 1, H2bl 0.774217
PPM1M protein phosphatase, Mg2+/Mn2+ dependent, 1M 0.682635
NT5C2 5'-nucleotidase, cytosolic II 0.602429
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.602429
NCAN neurocan 0.602429
PALB2 partner and localizer of BRCA2 0.5306
HLA-B major histocompatibility complex, class I, B 0.52461
ARL4P ADP-ribosylation factor-like 4 pseudogene 0.52461
INTS7 integrator complex subunit 7 0.486425
DGKH diacylglycerol kinase, eta 0.486425
PDE10A phosphodiesterase 10A 0.486425
FBLN1 fibulin 1 0.486425
ZSWIM6 zinc finger, SWIM-type containing 6 0.449873
FAM110C family with sequence similarity 110, member C 0.438544
MARK1 MAP/microtubule affinity-regulating kinase 1 0.429338
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.429338
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.414708
MCTP1 multiple C2 domains, transmembrane 1 0.403461
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.403461
C11ORF80 chromosome 11 open reading frame 80 0.368757
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.368757
SNX19 sorting nexin 19 0.345945
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.345945
DOK5 docking protein 5 0.311576
HLA-A major histocompatibility complex, class I, A 0.311576
PTBP2 polypyrimidine tract binding protein 2 0.311576
DPYD dihydropyrimidine dehydrogenase 0.311576
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.297866
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.285417
LAMP3 lysosomal-associated membrane protein 3 0.285417
CMKLR1 chemerin chemokine-like receptor 1 0.264872
CDC25B cell division cycle 25B 0.256228
TLE4 transducin-like enhancer of split 4 0.256228
TMEM132C transmembrane protein 132C 0.256228
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.256228
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.256228
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.256228
CTSF cathepsin F 0.256228
CGNL1 cingulin-like 1 0.256228
IFI44 interferon-induced protein 44 0.256228
SKAP1 src kinase associated phosphoprotein 1 0.256228
NFIA nuclear factor I/A 0.197766
SGOL1 shugoshin-like 1 (S. pombe) 0.197766
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.197766
LMAN2L lectin, mannose-binding 2-like 0.197766
TTC39B tetratricopeptide repeat domain 39B 0.197766
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 0.197766
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.197766
ATP8B3 ATPase, aminophospholipid transporter, class I, type 8B, member 3 0.197766
TDRD9 tudor domain containing 9 0.197766
KIF18A kinesin family member 18A 0.197766
ZNF490 zinc finger protein 490 0.197766
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.197766
DPY19L3 dpy-19-like 3 (C. elegans) 0.197766
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.197766
GPM6A glycoprotein M6A 0.197766
GRIK5 glutamate receptor, ionotropic, kainate 5 0.197766
SLITRK1 SLIT and NTRK-like family, member 1 0.197766
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 0.197766
KIAA1211L KIAA1211-like 0.15771
C15ORF53 chromosome 15 open reading frame 53 0.15771
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.15771
GARNL3 GTPase activating Rap/RanGAP domain-like 3 0.15771
FOXO6 forkhead box O6 0.15771
MSRA methionine sulfoxide reductase A 0.15771
RASIP1 Ras interacting protein 1 0.15771
PARD6B par-6 family cell polarity regulator beta 0.15771
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.15771
NLRC5 NLR family, CARD domain containing 5 0.15771
KCNU1 potassium channel, subfamily U, member 1 0.126165
BRWD1 bromodomain and WD repeat domain containing 1 0.126165
SYNE1 spectrin repeat containing, nuclear envelope 1 0.126165
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.126165
SPRED1 sprouty-related, EVH1 domain containing 1 0.126165
GPR65 G protein-coupled receptor 65 0.126165
FGR FGR proto-oncogene, Src family tyrosine kinase 0.126165
KIAA1549L KIAA1549-like 0.126165
TENM4 teneurin transmembrane protein 4 0.126165
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 0.126165
PRSS3 protease, serine, 3 0.126165
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.126165
TMEM63C transmembrane protein 63C 0.100789
ADAMTS14 ADAM metallopeptidase with thrombospondin type 1 motif, 14 0.100789
LINC00596 long intergenic non-protein coding RNA 596 0.100789
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.100789
AUTS2 autism susceptibility candidate 2 0.100789
DLC1 DLC1 Rho GTPase activating protein 0.100789
FAM189A2 family with sequence similarity 189, member A2 0.100789
IRF2BP2 interferon regulatory factor 2 binding protein 2 0.100789
PDZD8 PDZ domain containing 8 0.100789
NPAS3 neuronal PAS domain protein 3 0.100789
ZNF385D zinc finger protein 385D 0.100789
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 0.080593
SIAE sialic acid acetylesterase 0.080593
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.080593
C15ORF32 chromosome 15 open reading frame 32 0.080593
GFI1B growth factor independent 1B transcription repressor 0.080593
OLFM3 olfactomedin 3 0.080593
RPL10AP3 ribosomal protein L10a pseudogene 3 0.080593
OR3A2 olfactory receptor, family 3, subfamily A, member 2 0.080593
CAPN10 calpain 10 0.080593
ABLIM1 actin binding LIM protein 1 0.064973
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 0.064973
NMUR2 neuromedin U receptor 2 0.064973
KIAA0355 KIAA0355 0.064973
THOC1 THO complex 1 0.064973
SUMF1 sulfatase modifying factor 1 0.064973
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.052255
COMMD10 COMM domain containing 10 0.052255
ZMIZ1 zinc finger, MIZ-type containing 1 0.052255
NEBL nebulette 0.052255
FAM126A family with sequence similarity 126, member A 0.052255
WSCD2 WSC domain containing 2 0.052255
KRTDAP keratinocyte differentiation-associated protein 0.052255
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 0.043246
ZDBF2 zinc finger, DBF-type containing 2 0.043246
DNAH11 dynein, axonemal, heavy chain 11 0.043246
CD276 CD276 molecule 0.043246
PCBP3 poly(rC) binding protein 3 0.043246
CNTN1 contactin 1 0.043246
NGFR nerve growth factor receptor 0.043246
SLC45A4 solute carrier family 45, member 4 0.043246
DFNB31 deafness, autosomal recessive 31 0.043246
CTSH cathepsin H 0.043246
IRG1 immunoresponsive 1 homolog (mouse) 0.035343