bh domain binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains. (Gene Ontology, GO_0051400)
External Link http://amigo.geneontology.org/amigo/term/GO:0051400
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Genes

10 genes performing the bh domain binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L2 BCL2-like 2
BIK BCL2-interacting killer (apoptosis-inducing)
BOK BCL2-related ovarian killer
MCL1 myeloid cell leukemia 1
PXN paxillin