bezafibrate-6653 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the bezafibrate-6653 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADD2 adducin 2 (beta)
AK5 adenylate kinase 5
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASPN asporin
B9D1 B9 protein domain 1
BAIAP3 BAI1-associated protein 3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALCA calcitonin-related polypeptide alpha
CALD1 caldesmon 1
CCNO cyclin O
CD200 CD200 molecule
CD300C CD300c molecule
CDRT1 CMT1A duplicated region transcript 1
CFDP1 craniofacial development protein 1
CFLAR CASP8 and FADD-like apoptosis regulator
CLMN calmin (calponin-like, transmembrane)
CNTNAP2 contactin associated protein-like 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
COMT catechol-O-methyltransferase
CRHR2 corticotropin releasing hormone receptor 2
CYTH1 cytohesin 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPF3 D4, zinc and double PHD fingers, family 3
DUSP9 dual specificity phosphatase 9
EFR3B EFR3 homolog B (S. cerevisiae)
EGR1 early growth response 1
EGR2 early growth response 2
ETV1 ets variant 1
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGBP Fc fragment of IgG binding protein
FGB fibrinogen beta chain
FGFR4 fibroblast growth factor receptor 4
FLT1 fms-related tyrosine kinase 1
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOLH1B folate hydrolase 1B
FRMPD1 FERM and PDZ domain containing 1
FYB FYN binding protein
GCK glucokinase (hexokinase 4)
GPR85 G protein-coupled receptor 85
HOXC5 homeobox C5
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCTD14 potassium channel tetramerization domain containing 14
KLF13 Kruppel-like factor 13
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT86 keratin 86, type II
KYNU kynureninase
LIMD2 LIM domain containing 2
MAGEA5 melanoma antigen family A5
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEP1B meprin A, beta
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCOR2 nuclear receptor corepressor 2
NDNF neuron-derived neurotrophic factor
NDOR1 NADPH dependent diflavin oxidoreductase 1
NLE1 notchless homolog 1 (Drosophila)
NOX1 NADPH oxidase 1
NPY5R neuropeptide Y receptor Y5
NR1H4 nuclear receptor subfamily 1, group H, member 4
OGG1 8-oxoguanine DNA glycosylase
OLFM1 olfactomedin 1
PAGE4 P antigen family, member 4 (prostate associated)
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PALM paralemmin
PAOX polyamine oxidase (exo-N4-amino)
PAPOLG poly(A) polymerase gamma
PBX2 pre-B-cell leukemia homeobox 2
PDCD6 programmed cell death 6
PDE4DIP phosphodiesterase 4D interacting protein
PMEL premelanosome protein
PPARD peroxisome proliferator-activated receptor delta
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1
RETN resistin
RGS5 regulator of G-protein signaling 5
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
SCARB1 scavenger receptor class B, member 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX29 sorting nexin 29
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMEM231 transmembrane protein 231
TMPRSS4 transmembrane protease, serine 4
TNK2 tyrosine kinase, non-receptor, 2
TTLL3 tubulin tyrosine ligase-like family member 3
WIZ widely interspaced zinc finger motifs
WNT5B wingless-type MMTV integration site family, member 5B
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF516 zinc finger protein 516
ZNF778 zinc finger protein 778

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAP2 ArfGAP with dual PH domains 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2P1 annexin A2 pseudogene 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC132 coiled-coil domain containing 132
CD70 CD70 molecule
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CHRDL1 chordin-like 1
CNGB3 cyclic nucleotide gated channel beta 3
CNTLN centlein, centrosomal protein
CST1 cystatin SN
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DNAL4 dynein, axonemal, light chain 4
ECM1 extracellular matrix protein 1
EDAR ectodysplasin A receptor
ELP6 elongator acetyltransferase complex subunit 6
ETNK2 ethanolamine kinase 2
FAM118A family with sequence similarity 118, member A
FBRS fibrosin
FBXO2 F-box protein 2
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
FOXN2 forkhead box N2
FRS2 fibroblast growth factor receptor substrate 2
GPC3 glypican 3
GTF2I general transcription factor IIi
H2AFJ H2A histone family, member J
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1T histone cluster 1, H1t
HIST1H2AK histone cluster 1, H2ak
HIST1H2BI histone cluster 1, H2bi
IL4R interleukin 4 receptor
IL7 interleukin 7
INO80D INO80 complex subunit D
IQSEC2 IQ motif and Sec7 domain 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0319L KIAA0319-like
KLK7 kallikrein-related peptidase 7
KRT8P12 keratin 8 pseudogene 12
LMNB1 lamin B1
LMO7 LIM domain 7
LYPD1 LY6/PLAUR domain containing 1
LYRM9 LYR motif containing 9
MEFV Mediterranean fever
MEIS1 Meis homeobox 1
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
NEK11 NIMA-related kinase 11
NKX3-2 NK3 homeobox 2
NXPE3 neurexophilin and PC-esterase domain family, member 3
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PELI1 pellino E3 ubiquitin protein ligase 1
PID1 phosphotyrosine interaction domain containing 1
PLCD1 phospholipase C, delta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB3 proline-rich protein BstNI subfamily 3
PROL1 proline rich, lacrimal 1
PRSS22 protease, serine, 22
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
SIX3 SIX homeobox 3
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPATA1 spermatogenesis associated 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TENM1 teneurin transmembrane protein 1
TMEM209 transmembrane protein 209
TMEM8B transmembrane protein 8B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC30A tetratricopeptide repeat domain 30A
TTLL7 tubulin tyrosine ligase-like family member 7
VGF VGF nerve growth factor inducible
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFP30 ZFP30 zinc finger protein
ZNF197 zinc finger protein 197
ZNF215 zinc finger protein 215
ZNF528 zinc finger protein 528
ZNF675 zinc finger protein 675
ZNF816 zinc finger protein 816