bezafibrate-4999 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bezafibrate-4999 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
AGRP agouti related neuropeptide
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APC adenomatous polyposis coli
ASIC4 acid sensing (proton gated) ion channel family member 4
BIRC3 baculoviral IAP repeat containing 3
C19ORF73 chromosome 19 open reading frame 73
C21ORF2 chromosome 21 open reading frame 2
C2ORF72 chromosome 2 open reading frame 72
CAPN9 calpain 9
CD209 CD209 molecule
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CLIC5 chloride intracellular channel 5
COL4A6 collagen, type IV, alpha 6
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DEPDC5 DEP domain containing 5
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DLK2 delta-like 2 homolog (Drosophila)
DOK2 docking protein 2, 56kDa
DOK5 docking protein 5
DPF1 D4, zinc and double PHD fingers family 1
ELP6 elongator acetyltransferase complex subunit 6
FILIP1L filamin A interacting protein 1-like
GJB3 gap junction protein, beta 3, 31kDa
GRIK5 glutamate receptor, ionotropic, kainate 5
GUK1 guanylate kinase 1
HABP2 hyaluronan binding protein 2
HAMP hepcidin antimicrobial peptide
HDLBP high density lipoprotein binding protein
HIST1H1T histone cluster 1, H1t
HOXB2 homeobox B2
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IFFO1 intermediate filament family orphan 1
IGFBP5 insulin-like growth factor binding protein 5
IL1B interleukin 1, beta
IL2 interleukin 2
IMPG2 interphotoreceptor matrix proteoglycan 2
INHBA inhibin, beta A
INSL4 insulin-like 4 (placenta)
JAM3 junctional adhesion molecule 3
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLHL22 kelch-like family member 22
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMB4 laminin, beta 4
LINC00597 long intergenic non-protein coding RNA 597
LRRN3 leucine rich repeat neuronal 3
MAP2K7 mitogen-activated protein kinase kinase 7
MAST3 microtubule associated serine/threonine kinase 3
MFAP5 microfibrillar associated protein 5
MMP3 matrix metallopeptidase 3
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NPTXR neuronal pentraxin receptor
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NXPH3 neurexophilin 3
OVOL1 ovo-like zinc finger 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PCDHGA8 protocadherin gamma subfamily A, 8
PDCD2 programmed cell death 2
PEG10 paternally expressed 10
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POF1B premature ovarian failure, 1B
PRB1 proline-rich protein BstNI subfamily 1
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRM protein tyrosine phosphatase, receptor type, M
RGS20 regulator of G-protein signaling 20
RND2 Rho family GTPase 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL10 ribosomal protein L10
RPL7 ribosomal protein L7
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SIDT2 SID1 transmembrane family, member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SOCS3 suppressor of cytokine signaling 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SPON2 spondin 2, extracellular matrix protein
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
STEAP4 STEAP family member 4
TCF3 transcription factor 3
TECPR2 tectonin beta-propeller repeat containing 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TONSL tonsoku-like, DNA repair protein
TREX1 three prime repair exonuclease 1
UBA6 ubiquitin-like modifier activating enzyme 6
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
VN1R1 vomeronasal 1 receptor 1
WNT16 wingless-type MMTV integration site family, member 16
ZNF613 zinc finger protein 613
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ADAM15 ADAM metallopeptidase domain 15
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BCL9 B-cell CLL/lymphoma 9
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
C22ORF29 chromosome 22 open reading frame 29
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC85C coiled-coil domain containing 85C
CGA glycoprotein hormones, alpha polypeptide
CHKB choline kinase beta
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CISH cytokine inducible SH2-containing protein
CLCN5 chloride channel, voltage-sensitive 5
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DOLPP1 dolichyldiphosphatase 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ETAA1 Ewing tumor-associated antigen 1
FKBP5 FK506 binding protein 5
FSD1 fibronectin type III and SPRY domain containing 1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPR1 G protein-coupled receptor 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMHA1 histocompatibility (minor) HA-1
IFI27 interferon, alpha-inducible protein 27
IL15RA interleukin 15 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRAK4 interleukin-1 receptor-associated kinase 4
LIN7B lin-7 homolog B (C. elegans)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MALL mal, T-cell differentiation protein-like
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MCOLN3 mucolipin 3
MMP9 matrix metallopeptidase 9
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVD mevalonate (diphospho) decarboxylase
NECAB3 N-terminal EF-hand calcium binding protein 3
NME5 NME/NM23 family member 5
NOL6 nucleolar protein 6 (RNA-associated)
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
PACS1 phosphofurin acidic cluster sorting protein 1
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PCF11 PCF11 cleavage and polyadenylation factor subunit
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMT2 protein-O-mannosyltransferase 2
PPT2 palmitoyl-protein thioesterase 2
PRKX protein kinase, X-linked
PRSS22 protease, serine, 22
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RANGAP1 Ran GTPase activating protein 1
RPAP1 RNA polymerase II associated protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SMYD5 SMYD family member 5
SPHK1 sphingosine kinase 1
SSFA2 sperm specific antigen 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
THRAP3 thyroid hormone receptor associated protein 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF3 transmembrane 7 superfamily member 3
TRABD TraB domain containing
TRIP10 thyroid hormone receptor interactor 10
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
VARS valyl-tRNA synthetase
WBP2 WW domain binding protein 2
XAB2 XPA binding protein 2
XYLT2 xylosyltransferase II
ZBTB6 zinc finger and BTB domain containing 6
ZNF226 zinc finger protein 226
ZNF286A zinc finger protein 286A
ZNF778 zinc finger protein 778
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN26 zinc finger and SCAN domain containing 26