betulinic acid-3281 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the betulinic acid-3281 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ATF3 activating transcription factor 3
B9D1 B9 protein domain 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BHLHE40 basic helix-loop-helix family, member e40
BIN1 bridging integrator 1
C19ORF66 chromosome 19 open reading frame 66
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1ORF54 chromosome 1 open reading frame 54
C2CD2L C2CD2-like
CAMTA2 calmodulin binding transcription activator 2
CCDC85C coiled-coil domain containing 85C
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CKLF chemokine-like factor
CLCF1 cardiotrophin-like cytokine factor 1
CORO7 coronin 7
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CTNS cystinosin, lysosomal cystine transporter
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DTNA dystrobrevin, alpha
EGR1 early growth response 1
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM49B family with sequence similarity 49, member B
FGFR1 fibroblast growth factor receptor 1
FKBP8 FK506 binding protein 8, 38kDa
FLT4 fms-related tyrosine kinase 4
FSCN1 fascin actin-bundling protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HOMER3 homer scaffolding protein 3
HPS1 Hermansky-Pudlak syndrome 1
ICAM1 intercellular adhesion molecule 1
INHA inhibin, alpha
INHBE inhibin, beta E
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JUN jun proto-oncogene
KIAA0319L KIAA0319-like
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
KRT15 keratin 15, type I
LGALS4 lectin, galactoside-binding, soluble, 4
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MBNL2 muscleblind-like splicing regulator 2
MCF2L MCF.2 cell line derived transforming sequence-like
MMP19 matrix metallopeptidase 19
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MYOF myoferlin
NBEAL2 neurobeachin-like 2
PALM paralemmin
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE4C phosphodiesterase 4C, cAMP-specific
PLK3 polo-like kinase 3
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
POPDC3 popeye domain containing 3
POU2F2 POU class 2 homeobox 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRSS53 protease, serine, 53
RAD54B RAD54 homolog B (S. cerevisiae)
RASAL2 RAS protein activator like 2
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RND1 Rho family GTPase 1
RNMT RNA (guanine-7-) methyltransferase
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMTN smoothelin
SPATA2L spermatogenesis associated 2-like
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYMPK symplekin
TBX19 T-box 19
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53I11 tumor protein p53 inducible protein 11
TRPM8 transient receptor potential cation channel, subfamily M, member 8
USF2 upstream transcription factor 2, c-fos interacting
USP2 ubiquitin specific peptidase 2
VPS37C vacuolar protein sorting 37 homolog C (S. cerevisiae)
ZC3H12A zinc finger CCCH-type containing 12A
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF444 zinc finger protein 444
ZNF862 zinc finger protein 862
ZW10 zw10 kinetochore protein

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADGRG2 adhesion G protein-coupled receptor G2
AMT aminomethyltransferase
APLP1 amyloid beta (A4) precursor-like protein 1
ARL15 ADP-ribosylation factor-like 15
ARRB1 arrestin, beta 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C19ORF73 chromosome 19 open reading frame 73
CAMKMT calmodulin-lysine N-methyltransferase
CCDC130 coiled-coil domain containing 130
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK20 cyclin-dependent kinase 20
CFAP44 cilia and flagella associated protein 44
CLCN6 chloride channel, voltage-sensitive 6
CLIP4 CAP-GLY domain containing linker protein family, member 4
CLSPN claspin
CSF1R colony stimulating factor 1 receptor
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EIF5A2 eukaryotic translation initiation factor 5A2
ELOVL4 ELOVL fatty acid elongase 4
ERCC2 excision repair cross-complementation group 2
EXD3 exonuclease 3'-5' domain containing 3
EXOC6B exocyst complex component 6B
FAM169A family with sequence similarity 169, member A
FKBP10 FK506 binding protein 10, 65 kDa
FLJ11710 uncharacterized protein FLJ11710
FLJ22184
FPGT fucose-1-phosphate guanylyltransferase
GADD45G growth arrest and DNA-damage-inducible, gamma
GATA4 GATA binding protein 4
GDAP1 ganglioside induced differentiation associated protein 1
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR27 G protein-coupled receptor 27
GSTA4 glutathione S-transferase alpha 4
HIST1H1E histone cluster 1, H1e
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HOXC10 homeobox C10
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ITGA10 integrin, alpha 10
KCTD7 potassium channel tetramerization domain containing 7
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LY6D lymphocyte antigen 6 complex, locus D
METTL16 methyltransferase like 16
MRPS18C mitochondrial ribosomal protein S18C
MSI1 musashi RNA-binding protein 1
MYO1F myosin IF
NHEJ1 nonhomologous end-joining factor 1
NPM3 nucleophosmin/nucleoplasmin 3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OSMR oncostatin M receptor
OTUD3 OTU deubiquitinase 3
OVOL1 ovo-like zinc finger 1
PDE12 phosphodiesterase 12
PHEX phosphate regulating endopeptidase homolog, X-linked
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRAMEF11 PRAME family member 11
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCE protein kinase C, epsilon
PTPN14 protein tyrosine phosphatase, non-receptor type 14
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3D RAB3D, member RAS oncogene family
RPL23AP32 ribosomal protein L23a pseudogene 32
SCD5 stearoyl-CoA desaturase 5
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDC3 syndecan 3
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SRPX sushi-repeat containing protein, X-linked
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARP TCR gamma alternate reading frame protein
TCHH trichohyalin
TLN1 talin 1
TOR4A torsin family 4, member A
TPK1 thiamin pyrophosphokinase 1
VEGFB vascular endothelial growth factor B
WDR62 WD repeat domain 62
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZBTB44 zinc finger and BTB domain containing 44
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF205 zinc finger protein 205