betulinic acid-1345 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the betulinic acid-1345 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ASB8 ankyrin repeat and SOCS box containing 8
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BAD BCL2-associated agonist of cell death
BEX1 brain expressed, X-linked 1
BMPR1A bone morphogenetic protein receptor, type IA
C10ORF2 chromosome 10 open reading frame 2
C16ORF58 chromosome 16 open reading frame 58
C22ORF29 chromosome 22 open reading frame 29
CAPN15 calpain 15
CCL4 chemokine (C-C motif) ligand 4
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL4A2 collagen, type IV, alpha 2
CYB561 cytochrome b561
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DYM dymeclin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGR3 early growth response 3
ERCC1 excision repair cross-complementation group 1
FH fumarate hydratase
FKBP4 FK506 binding protein 4, 59kDa
FOSL1 FOS-like antigen 1
FRY furry homolog (Drosophila)
G0S2 G0/G1 switch 2
G6PC3 glucose 6 phosphatase, catalytic, 3
GCAT glycine C-acetyltransferase
GEMIN4 gem (nuclear organelle) associated protein 4
GK3P glycerol kinase 3 pseudogene
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HSF1 heat shock transcription factor 1
HTRA2 HtrA serine peptidase 2
HYAL2 hyaluronoglucosaminidase 2
ICK intestinal cell (MAK-like) kinase
IDS iduronate 2-sulfatase
IL1RAP interleukin 1 receptor accessory protein
IL24 interleukin 24
INO80B INO80 complex subunit B
IVNS1ABP influenza virus NS1A binding protein
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KAZN kazrin, periplakin interacting protein
LIG3 ligase III, DNA, ATP-dependent
LPPR3 lipid phosphate phosphatase-related protein type 3
LZTR1 leucine-zipper-like transcription regulator 1
MAP4 microtubule-associated protein 4
MEF2D myocyte enhancer factor 2D
MSRB2 methionine sulfoxide reductase B2
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NLE1 notchless homolog 1 (Drosophila)
NQO1 NAD(P)H dehydrogenase, quinone 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PACS2 phosphofurin acidic cluster sorting protein 2
PCDHGB5 protocadherin gamma subfamily B, 5
PDCD11 programmed cell death 11
PDLIM7 PDZ and LIM domain 7 (enigma)
PYGB phosphorylase, glycogen; brain
RPP25 ribonuclease P/MRP 25kDa subunit
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae)
RSAD1 radical S-adenosyl methionine domain containing 1
RUFY3 RUN and FYVE domain containing 3
SBF1 SET binding factor 1
SDC2 syndecan 2
SEC24D SEC24 family member D
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SLC16A4 solute carrier family 16, member 4
SLC25A44 solute carrier family 25, member 44
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNRK SNF related kinase
SPPL2B signal peptide peptidase like 2B
STOML1 stomatin (EPB72)-like 1
SUGP1 SURP and G patch domain containing 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SURF1 surfeit 1
TCOF1 Treacher Collins-Franceschetti syndrome 1
TNF tumor necrosis factor
TNPO2 transportin 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSC22D4 TSC22 domain family, member 4
TXNL4A thioredoxin-like 4A
UBE2D4 ubiquitin-conjugating enzyme E2D 4 (putative)
UBTF upstream binding transcription factor, RNA polymerase I
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
VCX2 variable charge, X-linked 2
ZNF133 zinc finger protein 133
ZNF226 zinc finger protein 226
ZNF37BP zinc finger protein 37B, pseudogene
ZNF442 zinc finger protein 442
ZNF473 zinc finger protein 473
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ALDOC aldolase C, fructose-bisphosphate
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARG1 arginase 1
ATAD2 ATPase family, AAA domain containing 2
ATF3 activating transcription factor 3
BBC3 BCL2 binding component 3
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C21ORF91 chromosome 21 open reading frame 91
CAPN1 calpain 1, (mu/I) large subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC88C coiled-coil domain containing 88C
CCNE2 cyclin E2
CD1D CD1d molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CISH cytokine inducible SH2-containing protein
CLEC2B C-type lectin domain family 2, member B
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYTIP cytohesin 1 interacting protein
DUSP5 dual specificity phosphatase 5
E2F8 E2F transcription factor 8
EGLN1 egl-9 family hypoxia-inducible factor 1
EGR2 early growth response 2
ENO2 enolase 2 (gamma, neuronal)
FAM63B family with sequence similarity 63, member B
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GBE1 glucan (1,4-alpha-), branching enzyme 1
GJA1 gap junction protein, alpha 1, 43kDa
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPNMB glycoprotein (transmembrane) nmb
GPR18 G protein-coupled receptor 18
GPRC5C G protein-coupled receptor, class C, group 5, member C
GYS1 glycogen synthase 1 (muscle)
HCAR3 hydroxycarboxylic acid receptor 3
HILPDA hypoxia inducible lipid droplet-associated
IFT81 intraflagellar transport 81
INF2 inverted formin, FH2 and WH2 domain containing
INSIG2 insulin induced gene 2
IRX5 iroquois homeobox 5
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM3A lysine (K)-specific demethylase 3A
KRCC1 lysine-rich coiled-coil 1
LIG4 ligase IV, DNA, ATP-dependent
LRRK1 leucine-rich repeat kinase 1
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MX2 MX dynamin-like GTPase 2
MXI1 MAX interactor 1, dimerization protein
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYLIP myosin regulatory light chain interacting protein
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLA2G15 phospholipase A2, group XV
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNRC1 proline-rich nuclear receptor coactivator 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB23 RAB23, member RAS oncogene family
RAB33B RAB33B, member RAS oncogene family
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RLF rearranged L-myc fusion
RPL23AP32 ribosomal protein L23a pseudogene 32
SALL2 spalt-like transcription factor 2
SETD8 SET domain containing (lysine methyltransferase) 8
SLC25A40 solute carrier family 25, member 40
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SREBF1 sterol regulatory element binding transcription factor 1
TGM5 transglutaminase 5
TLR4 toll-like receptor 4
TMEM156 transmembrane protein 156
TMEM242 transmembrane protein 242
TMEM45A transmembrane protein 45A
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TXLNG taxilin gamma
TXNIP thioredoxin interacting protein
VASH1 vasohibin 1
VGLL4 vestigial-like family member 4
ZBTB10 zinc finger and BTB domain containing 10
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF212 zinc finger protein 212
ZNF222 zinc finger protein 222
ZNF395 zinc finger protein 395
ZNF654 zinc finger protein 654
ZNF665 zinc finger protein 665