betazole-6344 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the betazole-6344 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD2 abhydrolase domain containing 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ANKLE2 ankyrin repeat and LEM domain containing 2
ANKMY1 ankyrin repeat and MYND domain containing 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP24 Rho GTPase activating protein 24
ARHGAP35 Rho GTPase activating protein 35
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDKRB1 bradykinin receptor B1
C5ORF42 chromosome 5 open reading frame 42
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBS cystathionine-beta-synthase
CCNO cyclin O
CD58 CD58 molecule
CD6 CD6 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHKB choline kinase beta
CLDN18 claudin 18
CLTB clathrin, light chain B
CNTNAP2 contactin associated protein-like 2
CST4 cystatin S
CXORF21 chromosome X open reading frame 21
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DBF4B DBF4 zinc finger B
DDIT3 DNA-damage-inducible transcript 3
DNAH17 dynein, axonemal, heavy chain 17
E2F4 E2F transcription factor 4, p107/p130-binding
EDIL3 EGF-like repeats and discoidin I-like domains 3
EMP1 epithelial membrane protein 1
FADS3 fatty acid desaturase 3
FAM134B family with sequence similarity 134, member B
FGF5 fibroblast growth factor 5
FMOD fibromodulin
FYB FYN binding protein
GBP1 guanylate binding protein 1, interferon-inducible
HOXA1 homeobox A1
HOXB2 homeobox B2
HOXB5 homeobox B5
HOXC10 homeobox C10
IFIH1 interferon induced with helicase C domain 1
IGLJ3 immunoglobulin lambda joining 3
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITM2A integral membrane protein 2A
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4A lysine (K)-specific demethylase 4A
KIF1A kinesin family member 1A
KLF2 Kruppel-like factor 2
KLHL36 kelch-like family member 36
KLK12 kallikrein-related peptidase 12
LEF1 lymphoid enhancer-binding factor 1
LOX lysyl oxidase
LTC4S leukotriene C4 synthase
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP7 microtubule-associated protein 7
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDNF neuron-derived neurotrophic factor
NEK11 NIMA-related kinase 11
NFX1 nuclear transcription factor, X-box binding 1
NPIPB15 nuclear pore complex interacting protein family, member B15
PARP6 poly (ADP-ribose) polymerase family, member 6
PCOLCE procollagen C-endopeptidase enhancer
PDCD2 programmed cell death 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PIAS2 protein inhibitor of activated STAT, 2
PLIN2 perilipin 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRDX2 peroxiredoxin 2
PROL1 proline rich, lacrimal 1
PROX1 prospero homeobox 1
PRSS53 protease, serine, 53
PSD3 pleckstrin and Sec7 domain containing 3
PYHIN1 pyrin and HIN domain family, member 1
REEP1 receptor accessory protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPS3A ribosomal protein S3A
SCIN scinderin
SETD8 SET domain containing (lysine methyltransferase) 8
SIDT2 SID1 transmembrane family, member 2
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STBD1 starch binding domain 1
TAPBP TAP binding protein (tapasin)
TBC1D30 TBC1 domain family, member 30
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFCP2L1 transcription factor CP2-like 1
TRAPPC6A trafficking protein particle complex 6A
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
VCL vinculin
VWA1 von Willebrand factor A domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRG2 adhesion G protein-coupled receptor G2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALPK1 alpha-kinase 1
AMPD2 adenosine monophosphate deaminase 2
BAHD1 bromo adjacent homology domain containing 1
BCCIP BRCA2 and CDKN1A interacting protein
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BIK BCL2-interacting killer (apoptosis-inducing)
BTBD2 BTB (POZ) domain containing 2
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C9ORF114 chromosome 9 open reading frame 114
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCNJ cyclin J
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COQ6 coenzyme Q6 monooxygenase
CTC1 CTS telomere maintenance complex component 1
CTSD cathepsin D
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EDC3 enhancer of mRNA decapping 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM69A family with sequence similarity 69, member A
FBXL7 F-box and leucine-rich repeat protein 7
FZD3 frizzled class receptor 3
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GCHFR GTP cyclohydrolase I feedback regulator
GHR growth hormone receptor
GLCE glucuronic acid epimerase
GMEB1 glucocorticoid modulatory element binding protein 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GUSBP3 glucuronidase, beta pseudogene 3
HCG4 HLA complex group 4 (non-protein coding)
HIRA histone cell cycle regulator
HOXC5 homeobox C5
ICK intestinal cell (MAK-like) kinase
IL4R interleukin 4 receptor
ISYNA1 inositol-3-phosphate synthase 1
KATNBL1 katanin p80 subunit B-like 1
KDM5C lysine (K)-specific demethylase 5C
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LINC00341 long intergenic non-protein coding RNA 341
LMBR1L limb development membrane protein 1-like
LPAR6 lysophosphatidic acid receptor 6
MAPK3 mitogen-activated protein kinase 3
MCM9 minichromosome maintenance complex component 9
MCTP1 multiple C2 domains, transmembrane 1
MOSPD3 motile sperm domain containing 3
MPDU1 mannose-P-dolichol utilization defect 1
MPI mannose phosphate isomerase
MSL2 male-specific lethal 2 homolog (Drosophila)
MVP major vault protein
NCS1 neuronal calcium sensor 1
NDRG4 NDRG family member 4
NECAP2 NECAP endocytosis associated 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRTN neurturin
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PALMD palmdelphin
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PISD phosphatidylserine decarboxylase
POMT2 protein-O-mannosyltransferase 2
PROSER1 proline and serine rich 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RANBP17 RAN binding protein 17
RGL2 ral guanine nucleotide dissociation stimulator-like 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF141 ring finger protein 141
RNF170 ring finger protein 170
RPAP1 RNA polymerase II associated protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAI suppressor of cancer cell invasion
SCRN3 secernin 3
SDF2 stromal cell-derived factor 2
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STIM1 stromal interaction molecule 1
TAGLN3 transgelin 3
TESK2 testis-specific kinase 2
TMEM156 transmembrane protein 156
TMEM51 transmembrane protein 51
TMEM8A transmembrane protein 8A
TNRC6B trinucleotide repeat containing 6B
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF5 TNF receptor-associated factor 5
TRIM58 tripartite motif containing 58
UBIAD1 UbiA prenyltransferase domain containing 1
URGCP upregulator of cell proliferation
WDR18 WD repeat domain 18
ZNF606 zinc finger protein 606
ZNF675 zinc finger protein 675
ZSCAN26 zinc finger and SCAN domain containing 26