betamethasone-6728 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the betamethasone-6728 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACVR1B activin A receptor, type IB
ADPRH ADP-ribosylarginine hydrolase
APOM apolipoprotein M
ATF5 activating transcription factor 5
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BMP1 bone morphogenetic protein 1
BTN3A2 butyrophilin, subfamily 3, member A2
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CAMTA1 calmodulin binding transcription activator 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CDK2 cyclin-dependent kinase 2
CELF2 CUGBP, Elav-like family member 2
CHGA chromogranin A
CNTNAP2 contactin associated protein-like 2
COL14A1 collagen, type XIV, alpha 1
COMMD4 COMM domain containing 4
DCTN2 dynactin 2 (p50)
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLX5 distal-less homeobox 5
DNPEP aspartyl aminopeptidase
DUSP1 dual specificity phosphatase 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ETV1 ets variant 1
EVI2A ecotropic viral integration site 2A
FGF12 fibroblast growth factor 12
FLJ42627 uncharacterized LOC645644
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FMO5 flavin containing monooxygenase 5
FMOD fibromodulin
FOXN3 forkhead box N3
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLP1R glucagon-like peptide 1 receptor
GLUL glutamate-ammonia ligase
HOXC5 homeobox C5
HPS1 Hermansky-Pudlak syndrome 1
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IFT27 intraflagellar transport 27
IL1RN interleukin 1 receptor antagonist
IL6R interleukin 6 receptor
IRS2 insulin receptor substrate 2
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIAA1467 KIAA1467
KRT6A keratin 6A, type II
LAMC2 laminin, gamma 2
MAB21L1 mab-21-like 1 (C. elegans)
MON2 MON2 homolog (S. cerevisiae)
MPPE1 metallophosphoesterase 1
MRPL20 mitochondrial ribosomal protein L20
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MUC8 mucin 8
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYO7A myosin VIIA
NAV2 neuron navigator 2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NNMT nicotinamide N-methyltransferase
NPC1 Niemann-Pick disease, type C1
OCM2 oncomodulin 2
PARVA parvin, alpha
PGP phosphoglycolate phosphatase
PKLR pyruvate kinase, liver and RBC
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PRB1 proline-rich protein BstNI subfamily 1
RGS12 regulator of G-protein signaling 12
ROR2 receptor tyrosine kinase-like orphan receptor 2
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
SCARB1 scavenger receptor class B, member 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SEPP1 selenoprotein P, plasma, 1
SNAI2 snail family zinc finger 2
SOCS3 suppressor of cytokine signaling 3
SPON1 spondin 1, extracellular matrix protein
STK16 serine/threonine kinase 16
STX7 syntaxin 7
TECTA tectorin alpha
TEKT2 tektin 2 (testicular)
TFCP2L1 transcription factor CP2-like 1
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
THPO thrombopoietin
TLR2 toll-like receptor 2
TMEM231 transmembrane protein 231
TNIK TRAF2 and NCK interacting kinase
TTC30A tetratricopeptide repeat domain 30A
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZC3H7B zinc finger CCCH-type containing 7B
ZHX3 zinc fingers and homeoboxes 3
ZNF41 zinc finger protein 41
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
ANXA10 annexin A10
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
C14ORF105 chromosome 14 open reading frame 105
C17ORF70 chromosome 17 open reading frame 70
CCDC106 coiled-coil domain containing 106
CDHR2 cadherin-related family member 2
CENPO centromere protein O
CEP170B centrosomal protein 170B
CISH cytokine inducible SH2-containing protein
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRMP1 collapsin response mediator protein 1
DSPP dentin sialophosphoprotein
ELSPBP1 epididymal sperm binding protein 1
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM13C family with sequence similarity 13, member C
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO2 F-box protein 2
FLT4 fms-related tyrosine kinase 4
FRS3 fibroblast growth factor receptor substrate 3
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUZ fuzzy planar cell polarity protein
GLDC glycine dehydrogenase (decarboxylating)
GMPR guanosine monophosphate reductase
GPX2 glutathione peroxidase 2
GRAMD1C GRAM domain containing 1C
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HDAC5 histone deacetylase 5
HDAC7 histone deacetylase 7
HOOK1 hook microtubule-tethering protein 1
HOXA7 homeobox A7
HSPB6 heat shock protein, alpha-crystallin-related, B6
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI44L interferon-induced protein 44-like
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IL1B interleukin 1, beta
IL36RN interleukin 36 receptor antagonist
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB7 integrin, beta 7
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA0556 KIAA0556
KIAA0894 KIAA0894 protein
KIRREL kin of IRRE like (Drosophila)
KRT34 keratin 34, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LIME1 Lck interacting transmembrane adaptor 1
LOC257152 uncharacterized LOC257152
LPAR4 lysophosphatidic acid receptor 4
LRP3 low density lipoprotein receptor-related protein 3
LRRK1 leucine-rich repeat kinase 1
MAP1S microtubule-associated protein 1S
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MILR1 mast cell immunoglobulin-like receptor 1
MYLIP myosin regulatory light chain interacting protein
MYO1D myosin ID
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NEUROD1 neuronal differentiation 1
NOL6 nucleolar protein 6 (RNA-associated)
NPIPB15 nuclear pore complex interacting protein family, member B15
NTSR1 neurotensin receptor 1 (high affinity)
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PACS1 phosphofurin acidic cluster sorting protein 1
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PCDH12 protocadherin 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKD2L2 polycystic kidney disease 2-like 2
PRAMEF10 PRAME family member 10
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAG2 recombination activating gene 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SH2D2A SH2 domain containing 2A
SIX1 SIX homeobox 1
SNTG1 syntrophin, gamma 1
SPTBN2 spectrin, beta, non-erythrocytic 2
TDRD3 tudor domain containing 3
TUBA3D tubulin, alpha 3d
TUBA4B tubulin, alpha 4b
UBTD1 ubiquitin domain containing 1
VWA1 von Willebrand factor A domain containing 1
WDR78 WD repeat domain 78
ZFHX3 zinc finger homeobox 3
ZNF426 zinc finger protein 426
ZNF574 zinc finger protein 574
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