beta-escin-3890 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the beta-escin-3890 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADM2 adrenomedullin 2
AMBP alpha-1-microglobulin/bikunin precursor
ARHGAP1 Rho GTPase activating protein 1
ARID5A AT rich interactive domain 5A (MRF1-like)
ARSD arylsulfatase D
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATF5 activating transcription factor 5
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BDKRB2 bradykinin receptor B2
BIRC3 baculoviral IAP repeat containing 3
BMP15 bone morphogenetic protein 15
BMP5 bone morphogenetic protein 5
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CDKN2A cyclin-dependent kinase inhibitor 2A
CEP41 centrosomal protein 41kDa
CGA glycoprotein hormones, alpha polypeptide
CLEC4M C-type lectin domain family 4, member M
COL5A2 collagen, type V, alpha 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CXORF21 chromosome X open reading frame 21
CYLC1 cylicin, basic protein of sperm head cytoskeleton 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DGKQ diacylglycerol kinase, theta 110kDa
DLC1 DLC1 Rho GTPase activating protein
DUSP4 dual specificity phosphatase 4
ELOVL2 ELOVL fatty acid elongase 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPN1 epsin 1
ERO1LB ERO1-like beta (S. cerevisiae)
FAM182B family with sequence similarity 182, member B
FAM212B family with sequence similarity 212, member B
FOS FBJ murine osteosarcoma viral oncogene homolog
FST follistatin
GEM GTP binding protein overexpressed in skeletal muscle
GSK3A glycogen synthase kinase 3 alpha
HIST1H4E histone cluster 1, H4e
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL6ST interleukin 6 signal transducer
IRF4 interferon regulatory factor 4
IRF8 interferon regulatory factor 8
KCNIP1 Kv channel interacting protein 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KIAA0754 KIAA0754
KLF12 Kruppel-like factor 12
KLHL28 kelch-like family member 28
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT8 keratin 8, type II
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LOC100131510 uncharacterized LOC100131510
LTC4S leukotriene C4 synthase
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2C myocyte enhancer factor 2C
MIER2 mesoderm induction early response 1, family member 2
MORC1 MORC family CW-type zinc finger 1
MT1E metallothionein 1E
MTMR1 myotubularin related protein 1
NOTCH3 notch 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRF1 nuclear respiratory factor 1
PARVA parvin, alpha
PCDH17 protocadherin 17
PDE4A phosphodiesterase 4A, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLD1 phospholipase D1, phosphatidylcholine-specific
PNPLA4 patatin-like phospholipase domain containing 4
POFUT1 protein O-fucosyltransferase 1
POM121L9P POM121 transmembrane nucleoporin-like 9, pseudogene
PPARD peroxisome proliferator-activated receptor delta
PTGIS prostaglandin I2 (prostacyclin) synthase
RCAN1 regulator of calcineurin 1
RHOH ras homolog family member H
RNF17 ring finger protein 17
RPS4Y1 ribosomal protein S4, Y-linked 1
SDC2 syndecan 2
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC43A3 solute carrier family 43, member 3
SNPH syntaphilin
SOGA1 suppressor of glucose, autophagy associated 1
TIMELESS timeless circadian clock
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TSPY1 testis specific protein, Y-linked 1
TTLL5 tubulin tyrosine ligase-like family member 5
VWA5A von Willebrand factor A domain containing 5A
WNT5A wingless-type MMTV integration site family, member 5A
ZNF154 zinc finger protein 154
ZNF304 zinc finger protein 304
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADTRP androgen-dependent TFPI-regulating protein
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD26 ankyrin repeat domain 26
ATP7B ATPase, Cu++ transporting, beta polypeptide
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
C5AR1 complement component 5a receptor 1
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CCDC71 coiled-coil domain containing 71
CCP110 centriolar coiled coil protein 110kDa
CDK3 cyclin-dependent kinase 3
CEP97 centrosomal protein 97kDa
CHPF chondroitin polymerizing factor
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CNR2 cannabinoid receptor 2 (macrophage)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOC2A double C2-like domains, alpha
DUSP2 dual specificity phosphatase 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ECHDC2 enoyl CoA hydratase domain containing 2
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC2 excision repair cross-complementation group 2
FAM110B family with sequence similarity 110, member B
FAM188A family with sequence similarity 188, member A
FGL1 fibrinogen-like 1
FZD4 frizzled class receptor 4
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GEMIN8 gem (nuclear organelle) associated protein 8
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
GRTP1 growth hormone regulated TBC protein 1
GSTM2 glutathione S-transferase mu 2 (muscle)
HDAC11 histone deacetylase 11
HIST1H3E histone cluster 1, H3e
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSPA1L heat shock 70kDa protein 1-like
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IQSEC2 IQ motif and Sec7 domain 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KIF13B kinesin family member 13B
KLF2 Kruppel-like factor 2
KLHL25 kelch-like family member 25
LGALS4 lectin, galactoside-binding, soluble, 4
LRP5L low density lipoprotein receptor-related protein 5-like
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP2 microtubule-associated protein 2
METTL21B methyltransferase like 21B
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
NCALD neurocalcin delta
NOL10 nucleolar protein 10
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PCDHB13 protocadherin beta 13
PIBF1 progesterone immunomodulatory binding factor 1
PLCD1 phospholipase C, delta 1
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
POLL polymerase (DNA directed), lambda
PORCN porcupine homolog (Drosophila)
PPARG peroxisome proliferator-activated receptor gamma
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRMT7 protein arginine methyltransferase 7
PVRL3 poliovirus receptor-related 3
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RIN1 Ras and Rab interactor 1
RLN1 relaxin 1
RPL13P5 ribosomal protein L13 pseudogene 5
SCUBE2 signal peptide, CUB domain, EGF-like 2
SENP7 SUMO1/sentrin specific peptidase 7
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOAT2 sterol O-acyltransferase 2
SOBP sine oculis binding protein homolog (Drosophila)
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRYD7 SPRY domain containing 7
STAB2 stabilin 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TBC1D19 TBC1 domain family, member 19
TBC1D2 TBC1 domain family, member 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TM6SF1 transmembrane 6 superfamily member 1
TMUB2 transmembrane and ubiquitin-like domain containing 2
TPK1 thiamin pyrophosphokinase 1
VAX2 ventral anterior homeobox 2
VWA1 von Willebrand factor A domain containing 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF8 zinc finger protein 8