beta-escin-3807 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the beta-escin-3807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
AJAP1 adherens junctions associated protein 1
APOL2 apolipoprotein L, 2
ARC activity-regulated cytoskeleton-associated protein
ARTN artemin
ATF3 activating transcription factor 3
ATF5 activating transcription factor 5
ATP10A ATPase, class V, type 10A
BAAT bile acid CoA:amino acid N-acyltransferase
BMP2 bone morphogenetic protein 2
C10ORF12 chromosome 10 open reading frame 12
C14ORF105 chromosome 14 open reading frame 105
C7ORF69 chromosome 7 open reading frame 69
CA5B carbonic anhydrase VB, mitochondrial
CADM1 cell adhesion molecule 1
CADM3 cell adhesion molecule 3
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC181 coiled-coil domain containing 181
CD200 CD200 molecule
CD52 CD52 molecule
CD6 CD6 molecule
CDK13 cyclin-dependent kinase 13
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
COPE coatomer protein complex, subunit epsilon
CPLX2 complexin 2
CSPG4 chondroitin sulfate proteoglycan 4
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
DIO2 deiodinase, iodothyronine, type II
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
EXPH5 exophilin 5
FGF4 fibroblast growth factor 4
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GEM GTP binding protein overexpressed in skeletal muscle
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR85 G protein-coupled receptor 85
GRM7 glutamate receptor, metabotropic 7
HIST1H1D histone cluster 1, H1d
HIST1H2BG histone cluster 1, H2bg
HIST1H3I histone cluster 1, H3i
HLF hepatic leukemia factor
HMOX1 heme oxygenase 1
HNF4A hepatocyte nuclear factor 4, alpha
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IGSF6 immunoglobulin superfamily, member 6
IL1RN interleukin 1 receptor antagonist
IL24 interleukin 24
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
JUN jun proto-oncogene
JUND jun D proto-oncogene
KITLG KIT ligand
LAMB4 laminin, beta 4
LPL lipoprotein lipase
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MEGF6 multiple EGF-like-domains 6
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEURL1 neuralized E3 ubiquitin protein ligase 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NUP50 nucleoporin 50kDa
OR1F2P olfactory receptor, family 1, subfamily F, member 2, pseudogene
OR7A10 olfactory receptor, family 7, subfamily A, member 10
PDE4DIP phosphodiesterase 4D interacting protein
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDIA2 protein disulfide isomerase family A, member 2
PGM5 phosphoglucomutase 5
PKNOX2 PBX/knotted 1 homeobox 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKCB protein kinase C, beta
PTGIS prostaglandin I2 (prostacyclin) synthase
RAB26 RAB26, member RAS oncogene family
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RND1 Rho family GTPase 1
RRAD Ras-related associated with diabetes
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SMG7 SMG7 nonsense mediated mRNA decay factor
STC2 stanniocalcin 2
SULT4A1 sulfotransferase family 4A, member 1
TGFB1 transforming growth factor, beta 1
TLX2 T-cell leukemia homeobox 2
TMPRSS6 transmembrane protease, serine 6
TSPAN8 tetraspanin 8
TTLL1 tubulin tyrosine ligase-like family member 1
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UNC13A unc-13 homolog A (C. elegans)
ZFPM2 zinc finger protein, FOG family member 2
ZNF235 zinc finger protein 235
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAP2 ArfGAP with dual PH domains 2
AGO4 argonaute RISC catalytic component 4
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIM1 absent in melanoma 1
AKAP5 A kinase (PRKA) anchor protein 5
AMT aminomethyltransferase
ANKH ANKH inorganic pyrophosphate transport regulator
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ATXN2 ataxin 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C1R complement component 1, r subcomponent
C1RL complement component 1, r subcomponent-like
CAMKMT calmodulin-lysine N-methyltransferase
CBX8 chromobox homolog 8
CEP83 centrosomal protein 83kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
COL9A2 collagen, type IX, alpha 2
DBF4B DBF4 zinc finger B
DHRS9 dehydrogenase/reductase (SDR family) member 9
DPY19L2P2 DPY19L2 pseudogene 2
ECM1 extracellular matrix protein 1
ELP6 elongator acetyltransferase complex subunit 6
EML4 echinoderm microtubule associated protein like 4
EXD3 exonuclease 3'-5' domain containing 3
FAM184A family with sequence similarity 184, member A
FAT4 FAT atypical cadherin 4
FBXO46 F-box protein 46
FMO4 flavin containing monooxygenase 4
FRS3 fibroblast growth factor receptor substrate 3
GPR21 G protein-coupled receptor 21
GPR4 G protein-coupled receptor 4
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GRB7 growth factor receptor-bound protein 7
GREB1L growth regulation by estrogen in breast cancer-like
GSDMD gasdermin D
HCFC1 host cell factor C1
HDAC11 histone deacetylase 11
HOXA7 homeobox A7
HOXC10 homeobox C10
HOXC4 homeobox C4
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL33 interleukin 33
IRF2BP1 interferon regulatory factor 2 binding protein 1
KIAA0513 KIAA0513
KIAA0556 KIAA0556
KIFC3 kinesin family member C3
KLHL25 kelch-like family member 25
LIMS2 LIM and senescent cell antigen-like domains 2
LIN7B lin-7 homolog B (C. elegans)
LOC157562 uncharacterized LOC157562
MEFV Mediterranean fever
NDP Norrie disease (pseudoglioma)
NPIPB3 nuclear pore complex interacting protein family, member B3
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PER3 period circadian clock 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODNL1 podocan-like 1
PRB3 proline-rich protein BstNI subfamily 3
PTPRU protein tyrosine phosphatase, receptor type, U
QPCTL glutaminyl-peptide cyclotransferase-like
RAB36 RAB36, member RAS oncogene family
RARS arginyl-tRNA synthetase
REEP1 receptor accessory protein 1
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF2 ring finger protein 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPH3A rabphilin 3A
SALL2 spalt-like transcription factor 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIRT6 sirtuin 6
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMR3A submaxillary gland androgen regulated protein 3A
SOX30 SRY (sex determining region Y)-box 30
SPTBN2 spectrin, beta, non-erythrocytic 2
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCEAL2 transcription elongation factor A (SII)-like 2
TENM4 teneurin transmembrane protein 4
TET3 tet methylcytosine dioxygenase 3
TFCP2L1 transcription factor CP2-like 1
THNSL1 threonine synthase-like 1 (S. cerevisiae)
THRAP3 thyroid hormone receptor associated protein 3
THRB thyroid hormone receptor, beta
TRIB2 tribbles pseudokinase 2
TSKU tsukushi, small leucine rich proteoglycan
ZNF137P zinc finger protein 137, pseudogene
ZNF219 zinc finger protein 219
ZNF334 zinc finger protein 334
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573