bergenin-3467 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bergenin-3467 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATXN7L3B ataxin 7-like 3B
BTBD7 BTB (POZ) domain containing 7
C4ORF29 chromosome 4 open reading frame 29
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC186 coiled-coil domain containing 186
CDC25A cell division cycle 25A
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CFDP1 craniofacial development protein 1
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CRMP1 collapsin response mediator protein 1
DCAF15 DDB1 and CUL4 associated factor 15
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EPOR erythropoietin receptor
ERC2-IT1 ERC2 intronic transcript 1
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FBXL18 F-box and leucine-rich repeat protein 18
FBXL7 F-box and leucine-rich repeat protein 7
FHL1 four and a half LIM domains 1
FLJ11710 uncharacterized protein FLJ11710
FSCN1 fascin actin-bundling protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAS7 growth arrest-specific 7
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRX3 glutaredoxin 3
GM2A GM2 ganglioside activator
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GNS glucosamine (N-acetyl)-6-sulfatase
GUK1 guanylate kinase 1
HFE hemochromatosis
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHA1 immunoglobulin heavy constant alpha 1
IL11 interleukin 11
IL1A interleukin 1, alpha
IL6ST interleukin 6 signal transducer
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JRK Jrk homolog (mouse)
JUNB jun B proto-oncogene
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KITLG KIT ligand
LAMP1 lysosomal-associated membrane protein 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP12 low density lipoprotein receptor-related protein 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAOB monoamine oxidase B
MAPK13 mitogen-activated protein kinase 13
MED18 mediator complex subunit 18
MED6 mediator complex subunit 6
MEFV Mediterranean fever
METTL7A methyltransferase like 7A
NCOA2 nuclear receptor coactivator 2
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NGLY1 N-glycanase 1
NLRX1 NLR family member X1
NRF1 nuclear respiratory factor 1
OVOL1 ovo-like zinc finger 1
PHF20 PHD finger protein 20
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTHLH parathyroid hormone-like hormone
PTPRS protein tyrosine phosphatase, receptor type, S
RABGAP1 RAB GTPase activating protein 1
RB1 retinoblastoma 1
RNFT1 ring finger protein, transmembrane 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SOX9 SRY (sex determining region Y)-box 9
STARD3 StAR-related lipid transfer (START) domain containing 3
STRN3 striatin, calmodulin binding protein 3
SYMPK symplekin
TGFB2 transforming growth factor, beta 2
TMEM242 transmembrane protein 242
TNPO2 transportin 2
TRIM36 tripartite motif containing 36
TRIO trio Rho guanine nucleotide exchange factor
TTLL3 tubulin tyrosine ligase-like family member 3
UPK3B uroplakin 3B
USP36 ubiquitin specific peptidase 36
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF287 zinc finger protein 287
ZNF652 zinc finger protein 652
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ADGRE5 adhesion G protein-coupled receptor E5
ALDOC aldolase C, fructose-bisphosphate
ALS2CL ALS2 C-terminal like
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ATAD5 ATPase family, AAA domain containing 5
BAGE B melanoma antigen
BGLAP bone gamma-carboxyglutamate (gla) protein
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CENPT centromere protein T
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CIC capicua transcriptional repressor
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTDNEP1 CTD nuclear envelope phosphatase 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEAF1 DEAF1 transcription factor
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
DVL1 dishevelled segment polarity protein 1
E4F1 E4F transcription factor 1
EDAR ectodysplasin A receptor
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENPEP glutamyl aminopeptidase (aminopeptidase A)
FAM50B family with sequence similarity 50, member B
FBXL15 F-box and leucine-rich repeat protein 15
FGF23 fibroblast growth factor 23
FMOD fibromodulin
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GMIP GEM interacting protein
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPATCH3 G patch domain containing 3
GSTM2 glutathione S-transferase mu 2 (muscle)
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
IGSF1 immunoglobulin superfamily, member 1
IPO8 importin 8
ITPKC inositol-trisphosphate 3-kinase C
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF13B kinesin family member 13B
KLK5 kallikrein-related peptidase 5
LMBR1L limb development membrane protein 1-like
LPAR4 lysophosphatidic acid receptor 4
LRRC49 leucine rich repeat containing 49
MAST3 microtubule associated serine/threonine kinase 3
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MT1HL1 metallothionein 1H-like 1
NRGN neurogranin (protein kinase C substrate, RC3)
NT5E 5'-nucleotidase, ecto (CD73)
NXPH4 neurexophilin 4
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE8B phosphodiesterase 8B
PHC1 polyhomeotic homolog 1 (Drosophila)
PIBF1 progesterone immunomodulatory binding factor 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPT2 palmitoyl-protein thioesterase 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
RAD9A RAD9 homolog A (S. pombe)
RNF126P1 ring finger protein 126 pseudogene 1
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SIX1 SIX homeobox 1
SLC22A14 solute carrier family 22, member 14
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
THRAP3 thyroid hormone receptor associated protein 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TPST1 tyrosylprotein sulfotransferase 1
TRABD TraB domain containing
TTBK2 tau tubulin kinase 2
UBQLN4 ubiquilin 4
UNC119 unc-119 homolog (C. elegans)
VAX2 ventral anterior homeobox 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR25 WD repeat domain 25
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF211 zinc finger protein 211
ZNF212 zinc finger protein 212
ZNF778 zinc finger protein 778