berberine-7143 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools


197 genes differentially expressed following the berberine-7143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AKAP13 A kinase (PRKA) anchor protein 13
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALS2CL ALS2 C-terminal like
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ATXN7L1 ataxin 7-like 1
AURKA aurora kinase A
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BTN3A1 butyrophilin, subfamily 3, member A1
CALML4 calmodulin-like 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC88C coiled-coil domain containing 88C
CCNG2 cyclin G2
CDK3 cyclin-dependent kinase 3
CEP162 centrosomal protein 162kDa
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTSK cathepsin K
DBP D site of albumin promoter (albumin D-box) binding protein
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETV1 ets variant 1
FAM49B family with sequence similarity 49, member B
FCMR Fc fragment of IgM receptor
FGF1 fibroblast growth factor 1 (acidic)
FGF13 fibroblast growth factor 13
FKBP10 FK506 binding protein 10, 65 kDa
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FZD1 frizzled class receptor 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GK glycerol kinase
HNF1B HNF1 homeobox B
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXC13 homeobox C13
HTT huntingtin
IFT74 intraflagellar transport 74
JAG1 jagged 1
MAPK14 mitogen-activated protein kinase 14
MECP2 methyl CpG binding protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MPPE1 metallophosphoesterase 1
MTSS1L metastasis suppressor 1-like
MXD4 MAX dimerization protein 4
MYB v-myb avian myeloblastosis viral oncogene homolog
NABP1 nucleic acid binding protein 1
NDE1 nudE neurodevelopment protein 1
NPM3 nucleophosmin/nucleoplasmin 3
NPR3 natriuretic peptide receptor 3
OCLN occludin
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDAP1 PDGFA associated protein 1
PDE8B phosphodiesterase 8B
PRDM10 PR domain containing 10
PTN pleiotrophin
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB2A RAB2A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS10 regulator of G-protein signaling 10
RRAGD Ras-related GTP binding D
SCD5 stearoyl-CoA desaturase 5
SETDB1 SET domain, bifurcated 1
SFTPB surfactant protein B
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa
SNAPC5 small nuclear RNA activating complex, polypeptide 5, 19kDa
SNX13 sorting nexin 13
SOCS3 suppressor of cytokine signaling 3
SPPL2B signal peptide peptidase like 2B
SRPX2 sushi-repeat containing protein, X-linked 2
STARD5 StAR-related lipid transfer (START) domain containing 5
STK17B serine/threonine kinase 17b
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SUN1 Sad1 and UNC84 domain containing 1
SYNPO synaptopodin
TBX2 T-box 2
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THOC5 THO complex 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM259 transmembrane protein 259
TOX thymocyte selection-associated high mobility group box
TRAK1 trafficking protein, kinesin binding 1
TRIM25 tripartite motif containing 25
TTC38 tetratricopeptide repeat domain 38
USP6NL USP6 N-terminal like
VEZT vezatin, adherens junctions transmembrane protein
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZFHX3 zinc finger homeobox 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF174 zinc finger protein 174
ZNF222 zinc finger protein 222
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACOT8 acyl-CoA thioesterase 8
AEN apoptosis enhancing nuclease
ANOS1 anosmin 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ATAD5 ATPase family, AAA domain containing 5
BDNF brain-derived neurotrophic factor
C12ORF43 chromosome 12 open reading frame 43
C17ORF80 chromosome 17 open reading frame 80
C9ORF91 chromosome 9 open reading frame 91
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC91 coiled-coil domain containing 91
CCRL2 chemokine (C-C motif) receptor-like 2
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CHST10 carbohydrate sulfotransferase 10
CTNNBIP1 catenin, beta interacting protein 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCLRE1A DNA cross-link repair 1A
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DSE dermatan sulfate epimerase
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERCC5 excision repair cross-complementation group 5
ERCC6 excision repair cross-complementation group 6
EVPL envoplakin
FAM102A family with sequence similarity 102, member A
FAM3A family with sequence similarity 3, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GRWD1 glutamate-rich WD repeat containing 1
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HSPB8 heat shock 22kDa protein 8
IFT46 intraflagellar transport 46
INCENP inner centromere protein antigens 135/155kDa
ING3 inhibitor of growth family, member 3
ISL1 ISL LIM homeobox 1
JMJD4 jumonji domain containing 4
JUNB jun B proto-oncogene
KIAA0753 KIAA0753
KIRREL kin of IRRE like (Drosophila)
KLC2 kinesin light chain 2
KLHL12 kelch-like family member 12
KRT8P12 keratin 8 pseudogene 12
LZTR1 leucine-zipper-like transcription regulator 1
MAST3 microtubule associated serine/threonine kinase 3
MCM3AP-AS1 MCM3AP antisense RNA 1
MOGS mannosyl-oligosaccharide glucosidase
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MUTYH mutY homolog
MYL5 myosin, light chain 5, regulatory
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NOV nephroblastoma overexpressed
NXPE3 neurexophilin and PC-esterase domain family, member 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARN poly(A)-specific ribonuclease
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLD3 phospholipase D family, member 3
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAD51AP1 RAD51 associated protein 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RANBP17 RAN binding protein 17
RBM47 RNA binding motif protein 47
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
ROGDI rogdi homolog (Drosophila)
RPL7A ribosomal protein L7a
SETD1B SET domain containing 1B
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SFMBT1 Scm-like with four mbt domains 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SNX16 sorting nexin 16
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
STARD13 StAR-related lipid transfer (START) domain containing 13
STX17 syntaxin 17
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
TGFB3 transforming growth factor, beta 3
TMC5 transmembrane channel-like 5
TMEM127 transmembrane protein 127
TMEM177 transmembrane protein 177
TRAPPC11 trafficking protein particle complex 11
TTBK2 tau tubulin kinase 2
TTC4 tetratricopeptide repeat domain 4
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR37 WD repeat domain 37
ZBED1 zinc finger, BED-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF415 zinc finger protein 415
ZNF574 zinc finger protein 574
ZXDC ZXD family zinc finger C