bepridil-4613 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the bepridil-4613 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABI2 abl-interactor 2
AKAP13 A kinase (PRKA) anchor protein 13
APOB apolipoprotein B
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGAP26 Rho GTPase activating protein 26
ARHGAP28 Rho GTPase activating protein 28
ASCL1 achaete-scute family bHLH transcription factor 1
ATF3 activating transcription factor 3
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF12 chromosome 10 open reading frame 12
C1ORF116 chromosome 1 open reading frame 116
C3 complement component 3
C9ORF9 chromosome 9 open reading frame 9
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD4 CD4 molecule
CDK10 cyclin-dependent kinase 10
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
CNOT4 CCR4-NOT transcription complex, subunit 4
COL3A1 collagen, type III, alpha 1
CRY2 cryptochrome circadian clock 2
CTSE cathepsin E
CXCL2 chemokine (C-X-C motif) ligand 2
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DHRS7 dehydrogenase/reductase (SDR family) member 7
DMBT1 deleted in malignant brain tumors 1
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DPYSL4 dihydropyrimidinase-like 4
EGFL7 EGF-like-domain, multiple 7
EGR1 early growth response 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXO5 exonuclease 5
FABP3 fatty acid binding protein 3, muscle and heart
FDPS farnesyl diphosphate synthase
FGF17 fibroblast growth factor 17
HDAC6 histone deacetylase 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL37 interleukin 37
IL6 interleukin 6
INSL3 insulin-like 3 (Leydig cell)
KLHL22 kelch-like family member 22
KRT17 keratin 17, type I
LINC00652 long intergenic non-protein coding RNA 652
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MFAP2 microfibrillar-associated protein 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MT1F metallothionein 1F
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NGF nerve growth factor (beta polypeptide)
OASL 2'-5'-oligoadenylate synthetase-like
OBSL1 obscurin-like 1
PCDH1 protocadherin 1
PCNX pecanex homolog (Drosophila)
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PRB4 proline-rich protein BstNI subfamily 4
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PURA purine-rich element binding protein A
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RTN1 reticulon 1
RUNX1 runt-related transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SCGB2A1 secretoglobin, family 2A, member 1
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC17A4 solute carrier family 17, member 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SORCS3 sortilin-related VPS10 domain containing receptor 3
SOS2 son of sevenless homolog 2 (Drosophila)
SPATA2L spermatogenesis associated 2-like
SPI1 Spi-1 proto-oncogene
STK24 serine/threonine kinase 24
STOM stomatin
SYP synaptophysin
TESPA1 thymocyte expressed, positive selection associated 1
THEMIS2 thymocyte selection associated family member 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB3 tribbles pseudokinase 3
TUBGCP2 tubulin, gamma complex associated protein 2
TYR tyrosinase
WDR62 WD repeat domain 62
ZFP36L2 ZFP36 ring finger protein-like 2
ZFPM2 zinc finger protein, FOG family member 2
ZNF219 zinc finger protein 219
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANOS1 anosmin 1
BAG4 BCL2-associated athanogene 4
BEX4 brain expressed, X-linked 4
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF71 chromosome 11 open reading frame 71
C1ORF56 chromosome 1 open reading frame 56
C9ORF40 chromosome 9 open reading frame 40
CDH7 cadherin 7, type 2
CISH cytokine inducible SH2-containing protein
CLIC3 chloride intracellular channel 3
CLSPN claspin
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNR2 cannabinoid receptor 2 (macrophage)
CPQ carboxypeptidase Q
DCAF13 DDB1 and CUL4 associated factor 13
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOLK dolichol kinase
DTX2 deltex 2, E3 ubiquitin ligase
EGF epidermal growth factor
EHF ets homologous factor
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FZD3 frizzled class receptor 3
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GOLGA8B golgin A8 family, member B
GPALPP1 GPALPP motifs containing 1
GPR176 G protein-coupled receptor 176
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRPR gastrin-releasing peptide receptor
GSTA3 glutathione S-transferase alpha 3
GTF2I general transcription factor IIi
HIST1H2AM histone cluster 1, H2am
HOXA1 homeobox A1
HOXA7 homeobox A7
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA2 heat shock 70kDa protein 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL7 interleukin 7
INF2 inverted formin, FH2 and WH2 domain containing
IQCG IQ motif containing G
KCTD20 potassium channel tetramerization domain containing 20
KIAA0319L KIAA0319-like
KRT8P12 keratin 8 pseudogene 12
MAGEA6 melanoma antigen family A6
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBIP MAP3K12 binding inhibitory protein 1
MYLIP myosin regulatory light chain interacting protein
NAG18 NAG18 mRNA
NDE1 nudE neurodevelopment protein 1
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NFS1 NFS1 cysteine desulfurase
NT5M 5',3'-nucleotidase, mitochondrial
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARP3 poly (ADP-ribose) polymerase family, member 3
PDGFRL platelet-derived growth factor receptor-like
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLAC8 placenta-specific 8
PLEKHA6 pleckstrin homology domain containing, family A member 6
PTER phosphotriesterase related
PTK7 protein tyrosine kinase 7 (inactive)
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RANBP6 RAN binding protein 6
RARS arginyl-tRNA synthetase
RRAGB Ras-related GTP binding B
SAMD9 sterile alpha motif domain containing 9
SCARA3 scavenger receptor class A, member 3
SCN1B sodium channel, voltage gated, type I beta subunit
SCRN3 secernin 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMR3A submaxillary gland androgen regulated protein 3A
SPAG4 sperm associated antigen 4
SPIDR scaffolding protein involved in DNA repair
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TMEM177 transmembrane protein 177
TMEM230 transmembrane protein 230
TMEM242 transmembrane protein 242
TRIM52 tripartite motif containing 52
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZNF180 zinc finger protein 180
ZNF227 zinc finger protein 227
ZNF239 zinc finger protein 239
ZNF606 zinc finger protein 606
ZW10 zw10 kinetochore protein