benzylpenicillin-6839 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the benzylpenicillin-6839 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACACB acetyl-CoA carboxylase beta
ADAM12 ADAM metallopeptidase domain 12
ADAM22 ADAM metallopeptidase domain 22
ADGRG1 adhesion G protein-coupled receptor G1
AMPH amphiphysin
APOM apolipoprotein M
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASB1 ankyrin repeat and SOCS box containing 1
ATP10A ATPase, class V, type 10A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C1ORF68 chromosome 1 open reading frame 68
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CDK6 cyclin-dependent kinase 6
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
COL13A1 collagen, type XIII, alpha 1
CPN2 carboxypeptidase N, polypeptide 2
CREBZF CREB/ATF bZIP transcription factor
CRYGD crystallin, gamma D
CTSE cathepsin E
CUL3 cullin 3
CUZD1 CUB and zona pellucida-like domains 1
DAGLA diacylglycerol lipase, alpha
DCN decorin
DIO2 deiodinase, iodothyronine, type II
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DUX1 double homeobox 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXP3 forkhead box P3
FRMD8 FERM domain containing 8
GAS7 growth arrest-specific 7
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GJA8 gap junction protein, alpha 8, 50kDa
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HFE hemochromatosis
HIST1H1T histone cluster 1, H1t
HLA-DOA major histocompatibility complex, class II, DO alpha
IL1R1 interleukin 1 receptor, type I
IQCC IQ motif containing C
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLK8 kallikrein-related peptidase 8
LGALS9 lectin, galactoside-binding, soluble, 9
LIN7A lin-7 homolog A (C. elegans)
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MALL mal, T-cell differentiation protein-like
MBNL2 muscleblind-like splicing regulator 2
MEF2C myocyte enhancer factor 2C
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSI1 musashi RNA-binding protein 1
MUC3B mucin 3B, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDRG2 NDRG family member 2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRAP nebulin-related anchoring protein
NUDC nudC nuclear distribution protein
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDH1 protocadherin 1
PCDHGA9 protocadherin gamma subfamily A, 9
PDE4DIP phosphodiesterase 4D interacting protein
PDGFA platelet-derived growth factor alpha polypeptide
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX1 PBX/knotted 1 homeobox 1
PLLP plasmolipin
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PRB3 proline-rich protein BstNI subfamily 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PVR poliovirus receptor
RB1 retinoblastoma 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RNF208 ring finger protein 208
RPS28 ribosomal protein S28
S100A8 S100 calcium binding protein A8
SAA3P serum amyloid A3 pseudogene
SCN1B sodium channel, voltage gated, type I beta subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC35E2 solute carrier family 35, member E2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
STATH statherin
TBX5 T-box 5
TCP11L1 t-complex 11, testis-specific-like 1
TMOD1 tropomodulin 1
TNNI3 troponin I type 3 (cardiac)
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
WDTC1 WD and tetratricopeptide repeats 1
YPEL1 yippee-like 1 (Drosophila)
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF155 zinc finger protein 155
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ANP32A-IT1 ANP32A intronic transcript 1
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BPGM 2,3-bisphosphoglycerate mutase
BTBD7 BTB (POZ) domain containing 7
C19ORF73 chromosome 19 open reading frame 73
C4ORF29 chromosome 4 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC69 coiled-coil domain containing 69
CCNO cyclin O
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CENPO centromere protein O
CFAP44 cilia and flagella associated protein 44
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN5 chloride channel, voltage-sensitive 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CRYBG3 beta-gamma crystallin domain containing 3
CUEDC1 CUE domain containing 1
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DEAF1 DEAF1 transcription factor
DOCK1 dedicator of cytokinesis 1
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
EXD3 exonuclease 3'-5' domain containing 3
FAM169A family with sequence similarity 169, member A
FLCN folliculin
GAMT guanidinoacetate N-methyltransferase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HDAC11 histone deacetylase 11
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT22 intraflagellar transport 22
IRF2 interferon regulatory factor 2
KREMEN2 kringle containing transmembrane protein 2
LIF leukemia inhibitory factor
LOC729164 hCG1732469
MEIS1 Meis homeobox 1
MVP major vault protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
NUBPL nucleotide binding protein-like
PARP16 poly (ADP-ribose) polymerase family, member 16
PHACTR4 phosphatase and actin regulator 4
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLA2G12A phospholipase A2, group XIIA
PLD2 phospholipase D2
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POMT2 protein-O-mannosyltransferase 2
POU2F1 POU class 2 homeobox 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTBP2 polypyrimidine tract binding protein 2
PTDSS2 phosphatidylserine synthase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB5B RAB5B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL13P5 ribosomal protein L13 pseudogene 5
SAYSD1 SAYSVFN motif domain containing 1
SCD5 stearoyl-CoA desaturase 5
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMIM14 small integral membrane protein 14
SSFA2 sperm specific antigen 2
STRN striatin, calmodulin binding protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR5 toll-like receptor 5
TMC5 transmembrane channel-like 5
UBE2O ubiquitin-conjugating enzyme E2O
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VAX2 ventral anterior homeobox 2
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF280D zinc finger protein 280D
ZNF282 zinc finger protein 282
ZNF286A zinc finger protein 286A
ZNF442 zinc finger protein 442
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF747 zinc finger protein 747