benzethonium chloride-7207 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the benzethonium chloride-7207 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
APOD apolipoprotein D
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARID4B AT rich interactive domain 4B (RBP1-like)
ATF3 activating transcription factor 3
BAG4 BCL2-associated athanogene 4
C1ORF61 chromosome 1 open reading frame 61
C8ORF4 chromosome 8 open reading frame 4
CA5BP1 carbonic anhydrase VB pseudogene 1
CCL16 chemokine (C-C motif) ligand 16
CCNG2 cyclin G2
CD40 CD40 molecule, TNF receptor superfamily member 5
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
COL14A1 collagen, type XIV, alpha 1
COL1A1 collagen, type I, alpha 1
CPD carboxypeptidase D
CST1 cystatin SN
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ETV5 ets variant 5
EXT1 exostosin glycosyltransferase 1
FAM163A family with sequence similarity 163, member A
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GH1 growth hormone 1
GLYAT glycine-N-acyltransferase
GSTA4 glutathione S-transferase alpha 4
HAPLN1 hyaluronan and proteoglycan link protein 1
HFE hemochromatosis
HIST1H3E histone cluster 1, H3e
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNMT histamine N-methyltransferase
HP haptoglobin
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INHBE inhibin, beta E
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
INSIG1 insulin induced gene 1
INSR insulin receptor
IRS2 insulin receptor substrate 2
ISG20 interferon stimulated exonuclease gene 20kDa
JADE2 jade family PHD finger 2
KIF1C kinesin family member 1C
KIF21B kinesin family member 21B
KLHL24 kelch-like family member 24
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEFV Mediterranean fever
METTL7A methyltransferase like 7A
MGC12488
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MITF microphthalmia-associated transcription factor
MRPL41 mitochondrial ribosomal protein L41
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NR1H4 nuclear receptor subfamily 1, group H, member 4
NUPR1 nuclear protein, transcriptional regulator, 1
OCA2 oculocutaneous albinism II
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRB4 proline-rich protein BstNI subfamily 4
RCAN3 RCAN family member 3
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RGS12 regulator of G-protein signaling 12
RGS14 regulator of G-protein signaling 14
RUNX1 runt-related transcription factor 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPINK1 serine peptidase inhibitor, Kazal type 1
STYK1 serine/threonine/tyrosine kinase 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TDRKH tudor and KH domain containing
THBS4 thrombospondin 4
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TOP3B topoisomerase (DNA) III beta
TRBC1 T cell receptor beta constant 1
TRIM2 tripartite motif containing 2
TSC22D3 TSC22 domain family, member 3
TUBA3C tubulin, alpha 3c
UBOX5 U-box domain containing 5
VEGFA vascular endothelial growth factor A
WASL Wiskott-Aldrich syndrome-like
ZNF37BP zinc finger protein 37B, pseudogene
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
AMD1 adenosylmethionine decarboxylase 1
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARID3A AT rich interactive domain 3A (BRIGHT-like)
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAK1 BCL2-antagonist/killer 1
BRPF1 bromodomain and PHD finger containing, 1
C7ORF43 chromosome 7 open reading frame 43
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CDR2L cerebellar degeneration-related protein 2-like
CEP97 centrosomal protein 97kDa
CERK ceramide kinase
CHMP6 charged multivesicular body protein 6
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CPTP ceramide-1-phosphate transfer protein
CSK c-src tyrosine kinase
DEGS1 delta(4)-desaturase, sphingolipid 1
ECHDC3 enoyl CoA hydratase domain containing 3
EVPL envoplakin
FAM172A family with sequence similarity 172, member A
FBRS fibrosin
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GHR growth hormone receptor
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GYS1 glycogen synthase 1 (muscle)
HAUS6 HAUS augmin-like complex, subunit 6
HCFC2 host cell factor C2
HSPA2 heat shock 70kDa protein 2
IP6K1 inositol hexakisphosphate kinase 1
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC61 leucine rich repeat containing 61
MAN2C1 mannosidase, alpha, class 2C, member 1
MAST3 microtubule associated serine/threonine kinase 3
MISP mitotic spindle positioning
MOSPD3 motile sperm domain containing 3
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTRF1 mitochondrial translational release factor 1
MYL5 myosin, light chain 5, regulatory
NBEAL2 neurobeachin-like 2
NOTCH1 notch 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PAQR3 progestin and adipoQ receptor family member III
PISD phosphatidylserine decarboxylase
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLE polymerase (DNA directed), epsilon, catalytic subunit
POLH polymerase (DNA directed), eta
PP14571 uncharacterized LOC100130449
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTK6 protein tyrosine kinase 6
PYCRL pyrroline-5-carboxylate reductase-like
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SAMHD1 SAM domain and HD domain 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNIP1 Smad nuclear interacting protein 1
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STARD13 StAR-related lipid transfer (START) domain containing 13
SUGP1 SURP and G patch domain containing 1
SYT17 synaptotagmin XVII
TBC1D31 TBC1 domain family, member 31
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM168 transmembrane protein 168
TMEM183A transmembrane protein 183A
TMEM2 transmembrane protein 2
TMEM62 transmembrane protein 62
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPST1 tyrosylprotein sulfotransferase 1
TPST2 tyrosylprotein sulfotransferase 2
TRAF5 TNF receptor-associated factor 5
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTC4 tetratricopeptide repeat domain 4
TUBGCP5 tubulin, gamma complex associated protein 5
USP20 ubiquitin specific peptidase 20
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR62 WD repeat domain 62
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB39 zinc finger and BTB domain containing 39
ZBTB6 zinc finger and BTB domain containing 6
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF268 zinc finger protein 268
ZNF468 zinc finger protein 468
ZNF557 zinc finger protein 557
ZNF668 zinc finger protein 668
ZNF787 zinc finger protein 787