benserazide-6722 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the benserazide-6722 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADARB1 adenosine deaminase, RNA-specific, B1
ANKLE2 ankyrin repeat and LEM domain containing 2
AOC2 amine oxidase, copper containing 2 (retina-specific)
APC adenomatous polyposis coli
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARR3 arrestin 3, retinal (X-arrestin)
ASPN asporin
ATG10 autophagy related 10
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BBC3 BCL2 binding component 3
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CASP10 caspase 10, apoptosis-related cysteine peptidase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CISH cytokine inducible SH2-containing protein
CNTNAP2 contactin associated protein-like 2
CREBBP CREB binding protein
CTSF cathepsin F
DHRS7 dehydrogenase/reductase (SDR family) member 7
DIAPH2-AS1 DIAPH2 antisense RNA 1
EDA ectodysplasin A
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EFS embryonal Fyn-associated substrate
EHD2 EH-domain containing 2
ERCC5 excision repair cross-complementation group 5
ESRRG estrogen-related receptor gamma
FBXO2 F-box protein 2
FLJ11710 uncharacterized protein FLJ11710
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAN gigaxonin
GLB1L2 galactosidase, beta 1-like 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR1 G protein-coupled receptor 1
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUK1 guanylate kinase 1
HAP1 huntingtin-associated protein 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFT27 intraflagellar transport 27
IRF4 interferon regulatory factor 4
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT7 keratin 7, type II
KRT86 keratin 86, type II
KSR1 kinase suppressor of ras 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAK male germ cell-associated kinase
MASP2 mannan-binding lectin serine peptidase 2
MRPL52 mitochondrial ribosomal protein L52
MTCP1 mature T-cell proliferation 1
NIPAL2 NIPA-like domain containing 2
NOP16 NOP16 nucleolar protein
NRP2 neuropilin 2
OAZ3 ornithine decarboxylase antizyme 3
PDCD2 programmed cell death 2
PGK1 phosphoglycerate kinase 1
PGP phosphoglycolate phosphatase
PHOX2A paired-like homeobox 2a
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PKP4 plakophilin 4
PLXNC1 plexin C1
POU2F2 POU class 2 homeobox 2
PRDM11 PR domain containing 11
PRKCA protein kinase C, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PTN pleiotrophin
RAB36 RAB36, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RNF122 ring finger protein 122
RPAIN RPA interacting protein
RPL10 ribosomal protein L10
RPL14 ribosomal protein L14
RPLP2 ribosomal protein, large, P2
RPS11 ribosomal protein S11
SAYSD1 SAYSVFN motif domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFRP1 secreted frizzled-related protein 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNTG1 syntrophin, gamma 1
SOSTDC1 sclerostin domain containing 1
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
SUSD5 sushi domain containing 5
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TMCO6 transmembrane and coiled-coil domains 6
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
UBE2I ubiquitin-conjugating enzyme E2I
UTS2 urotensin 2
VNN2 vanin 2
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD17B abhydrolase domain containing 17B
ABT1 activator of basal transcription 1
ADAM15 ADAM metallopeptidase domain 15
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APOL6 apolipoprotein L, 6
ARRB2 arrestin, beta 2
ATG7 autophagy related 7
C14ORF93 chromosome 14 open reading frame 93
C17ORF70 chromosome 17 open reading frame 70
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC106 coiled-coil domain containing 106
CENPJ centromere protein J
CFAP69 cilia and flagella associated protein 69
CHM choroideremia (Rab escort protein 1)
CIR1 corepressor interacting with RBPJ, 1
CLCN6 chloride channel, voltage-sensitive 6
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRABP2 cellular retinoic acid binding protein 2
DBF4B DBF4 zinc finger B
DDA1 DET1 and DDB1 associated 1
DEAF1 DEAF1 transcription factor
DMTN dematin actin binding protein
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHX2 epoxide hydrolase 2, cytoplasmic
EXOC5 exocyst complex component 5
FABP4 fatty acid binding protein 4, adipocyte
FAM184A family with sequence similarity 184, member A
FBXL7 F-box and leucine-rich repeat protein 7
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FER fer (fps/fes related) tyrosine kinase
FNTB farnesyltransferase, CAAX box, beta
FURIN furin (paired basic amino acid cleaving enzyme)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
GRPR gastrin-releasing peptide receptor
GTF2I general transcription factor IIi
HOMER2 homer scaffolding protein 2
HP1BP3 heterochromatin protein 1, binding protein 3
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
KLC2 kinesin light chain 2
KLF13 Kruppel-like factor 13
KLHDC3 kelch domain containing 3
KLHL28 kelch-like family member 28
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIG4 ligase IV, DNA, ATP-dependent
LINS lines homolog (Drosophila)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MECR mitochondrial trans-2-enoyl-CoA reductase
MXD3 MAX dimerization protein 3
MYL9 myosin, light chain 9, regulatory
NABP2 nucleic acid binding protein 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFFR1 neuropeptide FF receptor 1
NPM3 nucleophosmin/nucleoplasmin 3
NRBP1 nuclear receptor binding protein 1
NRSN2 neurensin 2
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
ODF2 outer dense fiber of sperm tails 2
OSBP2 oxysterol binding protein 2
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PAX9 paired box 9
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PKM pyruvate kinase, muscle
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
QTRT1 queuine tRNA-ribosyltransferase 1
RAB5B RAB5B, member RAS oncogene family
RARS arginyl-tRNA synthetase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SCIN scinderin
SDC3 syndecan 3
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SIRT6 sirtuin 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMR3A submaxillary gland androgen regulated protein 3A
SPAG7 sperm associated antigen 7
SPTBN2 spectrin, beta, non-erythrocytic 2
TBC1D17 TBC1 domain family, member 17
TLN1 talin 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
ULBP2 UL16 binding protein 2
USP21 ubiquitin specific peptidase 21
VEZT vezatin, adherens junctions transmembrane protein
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF253 zinc finger protein 253
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408