benserazide-631 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the benserazide-631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
ACACA acetyl-CoA carboxylase alpha
ATAD5 ATPase family, AAA domain containing 5
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BCL7A B-cell CLL/lymphoma 7A
C6ORF47 chromosome 6 open reading frame 47
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAND1 cullin-associated and neddylation-dissociated 1
CASZ1 castor zinc finger 1
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHD1L chromodomain helicase DNA binding protein 1-like
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCC1 chloride channel CLIC-like 1
CRIPT cysteine-rich PDZ-binding protein
DEDD death effector domain containing
DGCR2 DiGeorge syndrome critical region gene 2
DLX2 distal-less homeobox 2
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
EID1 EP300 interacting inhibitor of differentiation 1
EIF5B eukaryotic translation initiation factor 5B
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FBXO42 F-box protein 42
FCHSD2 FCH and double SH3 domains 2
FERMT1 fermitin family member 1
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR1 fibroblast growth factor receptor 1
FUZ fuzzy planar cell polarity protein
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HFE hemochromatosis
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIST1H2BI histone cluster 1, H2bi
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
IGHM immunoglobulin heavy constant mu
IL6ST interleukin 6 signal transducer
INTS7 integrator complex subunit 7
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LPIN2 lipin 2
LRRN2 leucine rich repeat neuronal 2
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFN1 mitofusin 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MNT MAX network transcriptional repressor
MRPL57 mitochondrial ribosomal protein L57
MT1H metallothionein 1H
MYL10 myosin, light chain 10, regulatory
NCAPH2 non-SMC condensin II complex, subunit H2
NIPBL Nipped-B homolog (Drosophila)
NR4A2 nuclear receptor subfamily 4, group A, member 2
PADI1 peptidyl arginine deiminase, type I
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PHIP pleckstrin homology domain interacting protein
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PQLC1 PQ loop repeat containing 1
PRKD2 protein kinase D2
PTGES prostaglandin E synthase
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBPJ recombination signal binding protein for immunoglobulin kappa J region
REST RE1-silencing transcription factor
RGS14 regulator of G-protein signaling 14
RPE ribulose-5-phosphate-3-epimerase
RPL10 ribosomal protein L10
RPL18 ribosomal protein L18
RPL37A ribosomal protein L37a
SAT1 spermidine/spermine N1-acetyltransferase 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFTPC surfactant protein C
SHOX2 short stature homeobox 2
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SOS2 son of sevenless homolog 2 (Drosophila)
SOX15 SRY (sex determining region Y)-box 15
SPOP speckle-type POZ protein
SPX spexin hormone
SREBF1 sterol regulatory element binding transcription factor 1
SSFA2 sperm specific antigen 2
ST5 suppression of tumorigenicity 5
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STX12 syntaxin 12
TCF3 transcription factor 3
THTPA thiamine triphosphatase
THY1 Thy-1 cell surface antigen
TMEM161A transmembrane protein 161A
TNK1 tyrosine kinase, non-receptor, 1
TSC1 tuberous sclerosis 1
TSPAN6 tetraspanin 6
TXN thioredoxin
UBE2B ubiquitin-conjugating enzyme E2B
UBE3A ubiquitin protein ligase E3A
USP15 ubiquitin specific peptidase 15
VASP vasodilator-stimulated phosphoprotein
WDTC1 WD and tetratricopeptide repeats 1
ZMAT3 zinc finger, matrin-type 3
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ARRB2 arrestin, beta 2
ASB13 ankyrin repeat and SOCS box containing 13
ASCC1 activating signal cointegrator 1 complex subunit 1
ATG4A autophagy related 4A, cysteine peptidase
AXIN1 axin 1
B3GAT1 beta-1,3-glucuronyltransferase 1
B3GNT1
BCAR3 breast cancer anti-estrogen resistance 3
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BCORL1 BCL6 corepressor-like 1
BPHL biphenyl hydrolase-like (serine hydrolase)
BRD7 bromodomain containing 7
C1QTNF1 C1q and tumor necrosis factor related protein 1
C5ORF30 chromosome 5 open reading frame 30
CASP6 caspase 6, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN1 claudin 1
CLDN17 claudin 17
CPVL carboxypeptidase, vitellogenic-like
CREB3 cAMP responsive element binding protein 3
CRMP1 collapsin response mediator protein 1
CTCF CCCTC-binding factor (zinc finger protein)
DCTN4 dynactin 4 (p62)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EGLN2 egl-9 family hypoxia-inducible factor 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ERCC2 excision repair cross-complementation group 2
ERCC5 excision repair cross-complementation group 5
ERF Ets2 repressor factor
ETV7 ets variant 7
FAM46A family with sequence similarity 46, member A
FBXO3 F-box protein 3
FBXO31 F-box protein 31
FSD1 fibronectin type III and SPRY domain containing 1
FUBP3 far upstream element (FUSE) binding protein 3
GOLGA8B golgin A8 family, member B
GPATCH3 G patch domain containing 3
GRK5 G protein-coupled receptor kinase 5
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
ICAM3 intercellular adhesion molecule 3
KIAA0319L KIAA0319-like
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLC2 kinesin light chain 2
KLHL21 kelch-like family member 21
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHB luteinizing hormone beta polypeptide
LHFP lipoma HMGIC fusion partner
MED17 mediator complex subunit 17
MGMT O-6-methylguanine-DNA methyltransferase
MISP mitotic spindle positioning
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MUS81 MUS81 structure-specific endonuclease subunit
NCAPD2 non-SMC condensin I complex, subunit D2
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OFD1 oral-facial-digital syndrome 1
OR1F1 olfactory receptor, family 1, subfamily F, member 1
PISD phosphatidylserine decarboxylase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
POU5F1B POU class 5 homeobox 1B
PPP1R26 protein phosphatase 1, regulatory subunit 26
PRMT3 protein arginine methyltransferase 3
PRR15L proline rich 15-like
PTPRM protein tyrosine phosphatase, receptor type, M
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RTFDC1 replication termination factor 2 domain containing 1
S1PR4 sphingosine-1-phosphate receptor 4
SIRT6 sirtuin 6
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15
SNRPF small nuclear ribonucleoprotein polypeptide F
SPIN1 spindlin 1
SRBD1 S1 RNA binding domain 1
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SYNJ2BP synaptojanin 2 binding protein
TEX2 testis expressed 2
THOP1 thimet oligopeptidase 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM223 transmembrane protein 223
TNRC6B trinucleotide repeat containing 6B
TSPAN31 tetraspanin 31
UNC50 unc-50 homolog (C. elegans)
WRAP73 WD repeat containing, antisense to TP73
ZBED1 zinc finger, BED-type containing 1
ZNF143 zinc finger protein 143
ZNF185 zinc finger protein 185 (LIM domain)
ZNF189 zinc finger protein 189
ZNF74 zinc finger protein 74
ZNF816 zinc finger protein 816