Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the benserazide-631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
ACACA | acetyl-CoA carboxylase alpha |
ATAD5 | ATPase family, AAA domain containing 5 |
ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 |
BCL7A | B-cell CLL/lymphoma 7A |
C6ORF47 | chromosome 6 open reading frame 47 |
CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
CALM1 | calmodulin 1 (phosphorylase kinase, delta) |
CAND1 | cullin-associated and neddylation-dissociated 1 |
CASZ1 | castor zinc finger 1 |
CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
CHD1L | chromodomain helicase DNA binding protein 1-like |
CHRNA5 | cholinergic receptor, nicotinic, alpha 5 (neuronal) |
CLCC1 | chloride channel CLIC-like 1 |
CRIPT | cysteine-rich PDZ-binding protein |
DEDD | death effector domain containing |
DGCR2 | DiGeorge syndrome critical region gene 2 |
DLX2 | distal-less homeobox 2 |
DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
EID1 | EP300 interacting inhibitor of differentiation 1 |
EIF5B | eukaryotic translation initiation factor 5B |
EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
FBXO42 | F-box protein 42 |
FCHSD2 | FCH and double SH3 domains 2 |
FERMT1 | fermitin family member 1 |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FGFR1 | fibroblast growth factor receptor 1 |
FUZ | fuzzy planar cell polarity protein |
GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type |
HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
HFE | hemochromatosis |
HIF1AN | hypoxia inducible factor 1, alpha subunit inhibitor |
HIST1H2BI | histone cluster 1, H2bi |
HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
IGHM | immunoglobulin heavy constant mu |
IL6ST | interleukin 6 signal transducer |
INTS7 | integrator complex subunit 7 |
KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
LPIN2 | lipin 2 |
LRRN2 | leucine rich repeat neuronal 2 |
MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
MFN1 | mitofusin 1 |
MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
MNT | MAX network transcriptional repressor |
MRPL57 | mitochondrial ribosomal protein L57 |
MT1H | metallothionein 1H |
MYL10 | myosin, light chain 10, regulatory |
NCAPH2 | non-SMC condensin II complex, subunit H2 |
NIPBL | Nipped-B homolog (Drosophila) |
NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
PADI1 | peptidyl arginine deiminase, type I |
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 |
PDPK1 | 3-phosphoinositide dependent protein kinase 1 |
PHIP | pleckstrin homology domain interacting protein |
PPP1R12A | protein phosphatase 1, regulatory subunit 12A |
PQLC1 | PQ loop repeat containing 1 |
PRKD2 | protein kinase D2 |
PTGES | prostaglandin E synthase |
QTRT1 | queuine tRNA-ribosyltransferase 1 |
RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
RBPJ | recombination signal binding protein for immunoglobulin kappa J region |
REST | RE1-silencing transcription factor |
RGS14 | regulator of G-protein signaling 14 |
RPE | ribulose-5-phosphate-3-epimerase |
RPL10 | ribosomal protein L10 |
RPL18 | ribosomal protein L18 |
RPL37A | ribosomal protein L37a |
SAT1 | spermidine/spermine N1-acetyltransferase 1 |
SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
SFTPC | surfactant protein C |
SHOX2 | short stature homeobox 2 |
SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
SNRPA1 | small nuclear ribonucleoprotein polypeptide A' |
SOS2 | son of sevenless homolog 2 (Drosophila) |
SOX15 | SRY (sex determining region Y)-box 15 |
SPOP | speckle-type POZ protein |
SPX | spexin hormone |
SREBF1 | sterol regulatory element binding transcription factor 1 |
SSFA2 | sperm specific antigen 2 |
ST5 | suppression of tumorigenicity 5 |
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
STAT1 | signal transducer and activator of transcription 1, 91kDa |
STX12 | syntaxin 12 |
TCF3 | transcription factor 3 |
THTPA | thiamine triphosphatase |
THY1 | Thy-1 cell surface antigen |
TMEM161A | transmembrane protein 161A |
TNK1 | tyrosine kinase, non-receptor, 1 |
TSC1 | tuberous sclerosis 1 |
TSPAN6 | tetraspanin 6 |
TXN | thioredoxin |
UBE2B | ubiquitin-conjugating enzyme E2B |
UBE3A | ubiquitin protein ligase E3A |
USP15 | ubiquitin specific peptidase 15 |
VASP | vasodilator-stimulated phosphoprotein |
WDTC1 | WD and tetratricopeptide repeats 1 |
ZMAT3 | zinc finger, matrin-type 3 |
ZNF592 | zinc finger protein 592 |
Symbol | Name |
---|---|
ABHD17B | abhydrolase domain containing 17B |
ADAM15 | ADAM metallopeptidase domain 15 |
ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
ARRB2 | arrestin, beta 2 |
ASB13 | ankyrin repeat and SOCS box containing 13 |
ASCC1 | activating signal cointegrator 1 complex subunit 1 |
ATG4A | autophagy related 4A, cysteine peptidase |
AXIN1 | axin 1 |
B3GAT1 | beta-1,3-glucuronyltransferase 1 |
B3GNT1 | |
BCAR3 | breast cancer anti-estrogen resistance 3 |
BCKDHA | branched chain keto acid dehydrogenase E1, alpha polypeptide |
BCORL1 | BCL6 corepressor-like 1 |
BPHL | biphenyl hydrolase-like (serine hydrolase) |
BRD7 | bromodomain containing 7 |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
C5ORF30 | chromosome 5 open reading frame 30 |
CASP6 | caspase 6, apoptosis-related cysteine peptidase |
CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
CLDN1 | claudin 1 |
CLDN17 | claudin 17 |
CPVL | carboxypeptidase, vitellogenic-like |
CREB3 | cAMP responsive element binding protein 3 |
CRMP1 | collapsin response mediator protein 1 |
CTCF | CCCTC-binding factor (zinc finger protein) |
DCTN4 | dynactin 4 (p62) |
DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
EGLN2 | egl-9 family hypoxia-inducible factor 2 |
EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
ERCC2 | excision repair cross-complementation group 2 |
ERCC5 | excision repair cross-complementation group 5 |
ERF | Ets2 repressor factor |
ETV7 | ets variant 7 |
FAM46A | family with sequence similarity 46, member A |
FBXO3 | F-box protein 3 |
FBXO31 | F-box protein 31 |
FSD1 | fibronectin type III and SPRY domain containing 1 |
FUBP3 | far upstream element (FUSE) binding protein 3 |
GOLGA8B | golgin A8 family, member B |
GPATCH3 | G patch domain containing 3 |
GRK5 | G protein-coupled receptor kinase 5 |
HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') |
ICAM3 | intercellular adhesion molecule 3 |
KIAA0319L | KIAA0319-like |
KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
KLC2 | kinesin light chain 2 |
KLHL21 | kelch-like family member 21 |
LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
LHB | luteinizing hormone beta polypeptide |
LHFP | lipoma HMGIC fusion partner |
MED17 | mediator complex subunit 17 |
MGMT | O-6-methylguanine-DNA methyltransferase |
MISP | mitotic spindle positioning |
MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
MUS81 | MUS81 structure-specific endonuclease subunit |
NCAPD2 | non-SMC condensin I complex, subunit D2 |
OBFC1 | oligonucleotide/oligosaccharide-binding fold containing 1 |
OFD1 | oral-facial-digital syndrome 1 |
OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
PISD | phosphatidylserine decarboxylase |
PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
POU5F1B | POU class 5 homeobox 1B |
PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
PRMT3 | protein arginine methyltransferase 3 |
PRR15L | proline rich 15-like |
PTPRM | protein tyrosine phosphatase, receptor type, M |
RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
RTFDC1 | replication termination factor 2 domain containing 1 |
S1PR4 | sphingosine-1-phosphate receptor 4 |
SIRT6 | sirtuin 6 |
SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
SLC35A1 | solute carrier family 35 (CMP-sialic acid transporter), member A1 |
SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 |
SNRPF | small nuclear ribonucleoprotein polypeptide F |
SPIN1 | spindlin 1 |
SRBD1 | S1 RNA binding domain 1 |
SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
SYNJ2BP | synaptojanin 2 binding protein |
TEX2 | testis expressed 2 |
THOP1 | thimet oligopeptidase 1 |
TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
TMEM223 | transmembrane protein 223 |
TNRC6B | trinucleotide repeat containing 6B |
TSPAN31 | tetraspanin 31 |
UNC50 | unc-50 homolog (C. elegans) |
WRAP73 | WD repeat containing, antisense to TP73 |
ZBED1 | zinc finger, BED-type containing 1 |
ZNF143 | zinc finger protein 143 |
ZNF185 | zinc finger protein 185 (LIM domain) |
ZNF189 | zinc finger protein 189 |
ZNF74 | zinc finger protein 74 |
ZNF816 | zinc finger protein 816 |