benperidol-2475 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the benperidol-2475 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
AEN apoptosis enhancing nuclease
ANKRD40 ankyrin repeat domain 40
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
AREG amphiregulin
ATF7 activating transcription factor 7
BCAS1 breast carcinoma amplified sequence 1
C21ORF2 chromosome 21 open reading frame 2
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCSER2 coiled-coil serine-rich protein 2
CD40LG CD40 ligand
CD6 CD6 molecule
CDC14A cell division cycle 14A
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDHR2 cadherin-related family member 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFAP45 cilia and flagella associated protein 45
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CUL7 cullin 7
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCAF4 DDB1 and CUL4 associated factor 4
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DSG3 desmoglein 3
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA4 ephrin-A4
FGF22 fibroblast growth factor 22
FGFBP1 fibroblast growth factor binding protein 1
FLOT1 flotillin 1
FOXA1 forkhead box A1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPR107 G protein-coupled receptor 107
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOMER2 homer scaffolding protein 2
ICOSLG inducible T-cell co-stimulator ligand
INE1 inactivation escape 1 (non-protein coding)
KIF25 kinesin family member 25
KLF3 Kruppel-like factor 3 (basic)
KLHL36 kelch-like family member 36
LEFTY1 left-right determination factor 1
LIG3 ligase III, DNA, ATP-dependent
LIME1 Lck interacting transmembrane adaptor 1
LOXL3 lysyl oxidase-like 3
LRRC1 leucine rich repeat containing 1
LRRC6 leucine rich repeat containing 6
MAPK11 mitogen-activated protein kinase 11
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MBNL2 muscleblind-like splicing regulator 2
MLLT4-AS1 MLLT4 antisense RNA 1 (head to head)
MOB3B MOB kinase activator 3B
MVD mevalonate (diphospho) decarboxylase
MYL5 myosin, light chain 5, regulatory
MYLK myosin light chain kinase
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NAG18 NAG18 mRNA
NRG1 neuregulin 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUP88 nucleoporin 88kDa
OXCT2 3-oxoacid CoA transferase 2
PDGFB platelet-derived growth factor beta polypeptide
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLSCR3 phospholipid scramblase 3
POU4F1 POU class 4 homeobox 1
PQBP1 polyglutamine binding protein 1
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN2 protein tyrosine phosphatase, non-receptor type 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
S100A11 S100 calcium binding protein A11
SLC12A8 solute carrier family 12, member 8
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SNTA1 syntrophin, alpha 1
SNW1 SNW domain containing 1
SP100 SP100 nuclear antigen
SSH3 slingshot protein phosphatase 3
SSPN sarcospan
STOML1 stomatin (EPB72)-like 1
STS steroid sulfatase (microsomal), isozyme S
SYT5 synaptotagmin V
TMLHE trimethyllysine hydroxylase, epsilon
TMOD1 tropomodulin 1
TP53I3 tumor protein p53 inducible protein 3
TRAF4 TNF receptor-associated factor 4
TRIM3 tripartite motif containing 3
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TXNRD2 thioredoxin reductase 2
UPK3B uroplakin 3B
XYLB xylulokinase homolog (H. influenzae)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF235 zinc finger protein 235
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AATK apoptosis-associated tyrosine kinase
ABHD17B abhydrolase domain containing 17B
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM15 ADAM metallopeptidase domain 15
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASPN asporin
ATAD5 ATPase family, AAA domain containing 5
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
C21ORF91 chromosome 21 open reading frame 91
CAPN5 calpain 5
CCNT1 cyclin T1
CD300C CD300c molecule
CDKL3 cyclin-dependent kinase-like 3
CDR2L cerebellar degeneration-related protein 2-like
CECR1 cat eye syndrome chromosome region, candidate 1
CES3 carboxylesterase 3
CHM choroideremia (Rab escort protein 1)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNM3 dynamin 3
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOC2A double C2-like domains, alpha
DOK5 docking protein 5
DPEP2 dipeptidase 2
FBP1 fructose-1,6-bisphosphatase 1
FBXO31 F-box protein 31
FGL2 fibrinogen-like 2
GATA6 GATA binding protein 6
GJA1 gap junction protein, alpha 1, 43kDa
HIST1H3B histone cluster 1, H3b
HLA-DMA major histocompatibility complex, class II, DM alpha
ICAM5 intercellular adhesion molecule 5, telencephalin
IL12RB1 interleukin 12 receptor, beta 1
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCTD20 potassium channel tetramerization domain containing 20
LTBP3 latent transforming growth factor beta binding protein 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCPH1 microcephalin 1
MDM4 MDM4, p53 regulator
MST1 macrophage stimulating 1
MUM1 melanoma associated antigen (mutated) 1
MYH15 myosin, heavy chain 15
NCALD neurocalcin delta
NOD2 nucleotide-binding oligomerization domain containing 2
OCEL1 occludin/ELL domain containing 1
OXTR oxytocin receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCBP4 poly(rC) binding protein 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIPOX pipecolic acid oxidase
PIR pirin (iron-binding nuclear protein)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCD1 phospholipase C, delta 1
PLOD1 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
PNOC prepronociceptin
PTGES2 prostaglandin E synthase 2
PWAR5 Prader Willi/Angelman region RNA 5
RAB23 RAB23, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RPL13P5 ribosomal protein L13 pseudogene 5
SALL2 spalt-like transcription factor 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35F6 solute carrier family 35, member F6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SNAI1 snail family zinc finger 1
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
SSBP3 single stranded DNA binding protein 3
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAS2R10 taste receptor, type 2, member 10
TBC1D19 TBC1 domain family, member 19
TCTN2 tectonic family member 2
THBS4 thrombospondin 4
TMC7 transmembrane channel-like 7
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM25 tripartite motif containing 25
TUBA4B tubulin, alpha 4b
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
YPEL1 yippee-like 1 (Drosophila)
ZBTB39 zinc finger and BTB domain containing 39
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF219 zinc finger protein 219