bemegride-6668 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the bemegride-6668 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAM22 ADAM metallopeptidase domain 22
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADGRB2 adhesion G protein-coupled receptor B2
ADPRH ADP-ribosylarginine hydrolase
AK2 adenylate kinase 2
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP28 Rho GTPase activating protein 28
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
AURKC aurora kinase C
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAIAP3 BAI1-associated protein 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BDKRB2 bradykinin receptor B2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CARTPT CART prepropeptide
CASP5 caspase 5, apoptosis-related cysteine peptidase
CD8B CD8b molecule
CFAP70 cilia and flagella associated protein 70
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC4A C-type lectin domain family 4, member A
CLMN calmin (calponin-like, transmembrane)
DBF4B DBF4 zinc finger B
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DUSP9 dual specificity phosphatase 9
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ELSPBP1 epididymal sperm binding protein 1
FAM134B family with sequence similarity 134, member B
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FLOT1 flotillin 1
FOXP3 forkhead box P3
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GP6 glycoprotein VI (platelet)
HAP1 huntingtin-associated protein 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF1B HNF1 homeobox B
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
ICOSLG inducible T-cell co-stimulator ligand
INHA inhibin, alpha
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KDM4B lysine (K)-specific demethylase 4B
KLF12 Kruppel-like factor 12
KLF13 Kruppel-like factor 13
KRTAP9-9 keratin associated protein 9-9
LDB3 LIM domain binding 3
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LRRN3 leucine rich repeat neuronal 3
MAP2 microtubule-associated protein 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MTMR7 myotubularin related protein 7
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYEF2 myelin expression factor 2
MYRF myelin regulatory factor
NEK9 NIMA-related kinase 9
OLFM1 olfactomedin 1
PAX5 paired box 5
PDE4DIP phosphodiesterase 4D interacting protein
PDLIM4 PDZ and LIM domain 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKLR pyruvate kinase, liver and RBC
PLEKHS1 pleckstrin homology domain containing, family S member 1
RAB3D RAB3D, member RAS oncogene family
RASA3 RAS p21 protein activator 3
RERE arginine-glutamic acid dipeptide (RE) repeats
RGS7 regulator of G-protein signaling 7
RS1 retinoschisin 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RUNX1 runt-related transcription factor 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SMO smoothened, frizzled class receptor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SNX13 sorting nexin 13
SRP72 signal recognition particle 72kDa
STC1 stanniocalcin 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT13 synaptotagmin XIII
TADA3 transcriptional adaptor 3
TBX6 T-box 6
TGFB2 transforming growth factor, beta 2
THOC5 THO complex 5
TLR1 toll-like receptor 1
TLX2 T-cell leukemia homeobox 2
TMEM63A transmembrane protein 63A
TNP2 transition protein 2 (during histone to protamine replacement)
TRIM10 tripartite motif containing 10
TRIM31 tripartite motif containing 31
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UBXN1 UBX domain protein 1
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ACBD4 acyl-CoA binding domain containing 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C11ORF63 chromosome 11 open reading frame 63
C14ORF93 chromosome 14 open reading frame 93
C16ORF59 chromosome 16 open reading frame 59
C5ORF42 chromosome 5 open reading frame 42
C9ORF40 chromosome 9 open reading frame 40
CBX7 chromobox homolog 7
CCDC85C coiled-coil domain containing 85C
CD82 CD82 molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLDN1 claudin 1
CLDN14 claudin 14
CNGA1 cyclic nucleotide gated channel alpha 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEPTOR DEP domain containing MTOR-interacting protein
DTX2 deltex 2, E3 ubiquitin ligase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC2 excision repair cross-complementation group 2
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
GAS8 growth arrest-specific 8
GMIP GEM interacting protein
GMPR guanosine monophosphate reductase
GPC3 glypican 3
H2AFJ H2A histone family, member J
HDAC7 histone deacetylase 7
HIST1H2BN histone cluster 1, H2bn
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
HOXA4 homeobox A4
HOXC10 homeobox C10
IGSF3 immunoglobulin superfamily, member 3
INO80D INO80 complex subunit D
IQCG IQ motif containing G
IQSEC2 IQ motif and Sec7 domain 2
KATNBL1 katanin p80 subunit B-like 1
KIAA0232 KIAA0232
KIAA1549L KIAA1549-like
KIF13B kinesin family member 13B
LAX1 lymphocyte transmembrane adaptor 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MANEA mannosidase, endo-alpha
MCC mutated in colorectal cancers
MED22 mediator complex subunit 22
MEFV Mediterranean fever
MFSD6 major facilitator superfamily domain containing 6
MTERF4 mitochondrial transcription termination factor 4
MYO1F myosin IF
NEK11 NIMA-related kinase 11
NUP62CL nucleoporin 62kDa C-terminal like
NXPE3 neurexophilin and PC-esterase domain family, member 3
PARM1 prostate androgen-regulated mucin-like protein 1
PC pyruvate carboxylase
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLXNA3 plexin A3
PRSS53 protease, serine, 53
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
RARS arginyl-tRNA synthetase
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RIBC2 RIB43A domain with coiled-coils 2
RPH3AL rabphilin 3A-like (without C2 domains)
RRAGB Ras-related GTP binding B
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SENP7 SUMO1/sentrin specific peptidase 7
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SIX3 SIX homeobox 3
SLC46A3 solute carrier family 46, member 3
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMR3A submaxillary gland androgen regulated protein 3A
STON1 stonin 1
SYNPO synaptopodin
TCTN1 tectonic family member 1
TENM1 teneurin transmembrane protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLR2 toll-like receptor 2
TMEM212 transmembrane protein 212
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
USB1 U6 snRNA biogenesis 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WDR46 WD repeat domain 46
XAB2 XPA binding protein 2
ZBTB10 zinc finger and BTB domain containing 10
ZNF141 zinc finger protein 141
ZNF510 zinc finger protein 510
ZNF529 zinc finger protein 529