Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the bemegride-6668 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ACTG2 | actin, gamma 2, smooth muscle, enteric |
ADAM22 | ADAM metallopeptidase domain 22 |
ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
ADGRB2 | adhesion G protein-coupled receptor B2 |
ADPRH | ADP-ribosylarginine hydrolase |
AK2 | adenylate kinase 2 |
APOBEC2 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2 |
ARHGAP28 | Rho GTPase activating protein 28 |
ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
AURKC | aurora kinase C |
B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
BAIAP3 | BAI1-associated protein 3 |
BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
BDKRB2 | bradykinin receptor B2 |
CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
CARTPT | CART prepropeptide |
CASP5 | caspase 5, apoptosis-related cysteine peptidase |
CD8B | CD8b molecule |
CFAP70 | cilia and flagella associated protein 70 |
CFLAR | CASP8 and FADD-like apoptosis regulator |
CLEC4A | C-type lectin domain family 4, member A |
CLMN | calmin (calponin-like, transmembrane) |
DBF4B | DBF4 zinc finger B |
DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
DUSP9 | dual specificity phosphatase 9 |
EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
ELSPBP1 | epididymal sperm binding protein 1 |
FAM134B | family with sequence similarity 134, member B |
FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
FLOT1 | flotillin 1 |
FOXP3 | forkhead box P3 |
GALNT3 | polypeptide N-acetylgalactosaminyltransferase 3 |
GP6 | glycoprotein VI (platelet) |
HAP1 | huntingtin-associated protein 1 |
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
HNF1B | HNF1 homeobox B |
HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
ICOSLG | inducible T-cell co-stimulator ligand |
INHA | inhibin, alpha |
ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
KCNE2 | potassium channel, voltage gated subfamily E regulatory beta subunit 2 |
KDM4B | lysine (K)-specific demethylase 4B |
KLF12 | Kruppel-like factor 12 |
KLF13 | Kruppel-like factor 13 |
KRTAP9-9 | keratin associated protein 9-9 |
LDB3 | LIM domain binding 3 |
LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
LRRN3 | leucine rich repeat neuronal 3 |
MAP2 | microtubule-associated protein 2 |
MBL2 | mannose-binding lectin (protein C) 2, soluble |
MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
MTMR7 | myotubularin related protein 7 |
MUC4 | mucin 4, cell surface associated |
MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
MYEF2 | myelin expression factor 2 |
MYRF | myelin regulatory factor |
NEK9 | NIMA-related kinase 9 |
OLFM1 | olfactomedin 1 |
PAX5 | paired box 5 |
PDE4DIP | phosphodiesterase 4D interacting protein |
PDLIM4 | PDZ and LIM domain 4 |
PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
PKLR | pyruvate kinase, liver and RBC |
PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
RAB3D | RAB3D, member RAS oncogene family |
RASA3 | RAS p21 protein activator 3 |
RERE | arginine-glutamic acid dipeptide (RE) repeats |
RGS7 | regulator of G-protein signaling 7 |
RS1 | retinoschisin 1 |
RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
RUNX1 | runt-related transcription factor 1 |
SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
SMO | smoothened, frizzled class receptor |
SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
SNX13 | sorting nexin 13 |
SRP72 | signal recognition particle 72kDa |
STC1 | stanniocalcin 1 |
SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
SYT13 | synaptotagmin XIII |
TADA3 | transcriptional adaptor 3 |
TBX6 | T-box 6 |
TGFB2 | transforming growth factor, beta 2 |
THOC5 | THO complex 5 |
TLR1 | toll-like receptor 1 |
TLX2 | T-cell leukemia homeobox 2 |
TMEM63A | transmembrane protein 63A |
TNP2 | transition protein 2 (during histone to protamine replacement) |
TRIM10 | tripartite motif containing 10 |
TRIM31 | tripartite motif containing 31 |
TYMP | thymidine phosphorylase |
TYMS | thymidylate synthetase |
UBXN1 | UBX domain protein 1 |
UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
ZNF235 | zinc finger protein 235 |
Symbol | Name |
---|---|
AATK | apoptosis-associated tyrosine kinase |
ACBD4 | acyl-CoA binding domain containing 4 |
ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
ATAD5 | ATPase family, AAA domain containing 5 |
B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
C11ORF63 | chromosome 11 open reading frame 63 |
C14ORF93 | chromosome 14 open reading frame 93 |
C16ORF59 | chromosome 16 open reading frame 59 |
C5ORF42 | chromosome 5 open reading frame 42 |
C9ORF40 | chromosome 9 open reading frame 40 |
CBX7 | chromobox homolog 7 |
CCDC85C | coiled-coil domain containing 85C |
CD82 | CD82 molecule |
CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
CLDN1 | claudin 1 |
CLDN14 | claudin 14 |
CNGA1 | cyclic nucleotide gated channel alpha 1 |
CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
DEPTOR | DEP domain containing MTOR-interacting protein |
DTX2 | deltex 2, E3 ubiquitin ligase |
ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
ERCC2 | excision repair cross-complementation group 2 |
FAM188A | family with sequence similarity 188, member A |
FBXL7 | F-box and leucine-rich repeat protein 7 |
FGD1 | FYVE, RhoGEF and PH domain containing 1 |
GAS8 | growth arrest-specific 8 |
GMIP | GEM interacting protein |
GMPR | guanosine monophosphate reductase |
GPC3 | glypican 3 |
H2AFJ | H2A histone family, member J |
HDAC7 | histone deacetylase 7 |
HIST1H2BN | histone cluster 1, H2bn |
HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
HOXA1 | homeobox A1 |
HOXA4 | homeobox A4 |
HOXC10 | homeobox C10 |
IGSF3 | immunoglobulin superfamily, member 3 |
INO80D | INO80 complex subunit D |
IQCG | IQ motif containing G |
IQSEC2 | IQ motif and Sec7 domain 2 |
KATNBL1 | katanin p80 subunit B-like 1 |
KIAA0232 | KIAA0232 |
KIAA1549L | KIAA1549-like |
KIF13B | kinesin family member 13B |
LAX1 | lymphocyte transmembrane adaptor 1 |
LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
MANEA | mannosidase, endo-alpha |
MCC | mutated in colorectal cancers |
MED22 | mediator complex subunit 22 |
MEFV | Mediterranean fever |
MFSD6 | major facilitator superfamily domain containing 6 |
MTERF4 | mitochondrial transcription termination factor 4 |
MYO1F | myosin IF |
NEK11 | NIMA-related kinase 11 |
NUP62CL | nucleoporin 62kDa C-terminal like |
NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
PARM1 | prostate androgen-regulated mucin-like protein 1 |
PC | pyruvate carboxylase |
PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
PLXNA3 | plexin A3 |
PRSS53 | protease, serine, 53 |
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
RARS | arginyl-tRNA synthetase |
REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
RIBC2 | RIB43A domain with coiled-coils 2 |
RPH3AL | rabphilin 3A-like (without C2 domains) |
RRAGB | Ras-related GTP binding B |
SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
SENP7 | SUMO1/sentrin specific peptidase 7 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SIX3 | SIX homeobox 3 |
SLC46A3 | solute carrier family 46, member 3 |
SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
SMR3A | submaxillary gland androgen regulated protein 3A |
STON1 | stonin 1 |
SYNPO | synaptopodin |
TCTN1 | tectonic family member 1 |
TENM1 | teneurin transmembrane protein 1 |
TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
TLR2 | toll-like receptor 2 |
TMEM212 | transmembrane protein 212 |
TTLL1 | tubulin tyrosine ligase-like family member 1 |
TUBA4B | tubulin, alpha 4b |
USB1 | U6 snRNA biogenesis 1 |
USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
WDR46 | WD repeat domain 46 |
XAB2 | XPA binding protein 2 |
ZBTB10 | zinc finger and BTB domain containing 10 |
ZNF141 | zinc finger protein 141 |
ZNF510 | zinc finger protein 510 |
ZNF529 | zinc finger protein 529 |