beclometasone-3001 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the beclometasone-3001 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABHD6 abhydrolase domain containing 6
ADGRG2 adhesion G protein-coupled receptor G2
ADORA3 adenosine A3 receptor
AKAP5 A kinase (PRKA) anchor protein 5
ANO1 anoctamin 1, calcium activated chloride channel
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
AREG amphiregulin
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASCL1 achaete-scute family bHLH transcription factor 1
BDNF brain-derived neurotrophic factor
BEND5 BEN domain containing 5
CA9 carbonic anhydrase IX
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL11 chemokine (C-C motif) ligand 11
CD163 CD163 molecule
CDC14B cell division cycle 14B
CDRT1 CMT1A duplicated region transcript 1
COL14A1 collagen, type XIV, alpha 1
DCN decorin
DNAH2 dynein, axonemal, heavy chain 2
DPEP2 dipeptidase 2
DST dystonin
DUSP1 dual specificity phosphatase 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EN1 engrailed homeobox 1
EPAS1 endothelial PAS domain protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ESR1 estrogen receptor 1
FAM182B family with sequence similarity 182, member B
FAM65B family with sequence similarity 65, member B
FCMR Fc fragment of IgM receptor
FKBP5 FK506 binding protein 5
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GAL3ST4 galactose-3-O-sulfotransferase 4
GLG1 golgi glycoprotein 1
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C
HFE hemochromatosis
HOXB3 homeobox B3
ICOSLG inducible T-cell co-stimulator ligand
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1R2 interleukin 1 receptor, type II
ISG20 interferon stimulated exonuclease gene 20kDa
IVL involucrin
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KIAA0513 KIAA0513
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
LAMP1 lysosomal-associated membrane protein 1
MAOA monoamine oxidase A
MBD2 methyl-CpG binding domain protein 2
METTL7A methyltransferase like 7A
NBR2 neighbor of BRCA1 gene 2 (non-protein coding)
NCOR2 nuclear receptor corepressor 2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NOL10 nucleolar protein 10
NPR1 natriuretic peptide receptor 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
OLAH oleoyl-ACP hydrolase
ONECUT2 one cut homeobox 2
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDLIM3 PDZ and LIM domain 3
PER1 period circadian clock 1
PIGR polymeric immunoglobulin receptor
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POU3F1 POU class 3 homeobox 1
PRB4 proline-rich protein BstNI subfamily 4
PRKCH protein kinase C, eta
PTGDS prostaglandin D2 synthase 21kDa (brain)
PYCRL pyrroline-5-carboxylate reductase-like
PYY peptide YY
RAB11B RAB11B, member RAS oncogene family
RERE arginine-glutamic acid dipeptide (RE) repeats
RHOH ras homolog family member H
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC12A8 solute carrier family 12, member 8
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SYT1 synaptotagmin I
TF transferrin
THBS1 thrombospondin 1
TLE2 transducin-like enhancer of split 2
TMEM242 transmembrane protein 242
TMOD1 tropomodulin 1
TPST1 tyrosylprotein sulfotransferase 1
TSC22D3 TSC22 domain family, member 3
UTF1 undifferentiated embryonic cell transcription factor 1
VAMP5 vesicle-associated membrane protein 5
WDR55 WD repeat domain 55
WIZ widely interspaced zinc finger motifs
WNT2 wingless-type MMTV integration site family member 2
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ACVR2B activin A receptor, type IIB
ADGB androglobin
AEN apoptosis enhancing nuclease
ALG12 ALG12, alpha-1,6-mannosyltransferase
AOAH acyloxyacyl hydrolase (neutrophil)
AP3M2 adaptor-related protein complex 3, mu 2 subunit
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARHGAP12 Rho GTPase activating protein 12
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BTF3P11 basic transcription factor 3 pseudogene 11
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCL2 chemokine (C-C motif) ligand 2
CD38 CD38 molecule
CD9 CD9 molecule
CDKL3 cyclin-dependent kinase-like 3
CECR1 cat eye syndrome chromosome region, candidate 1
CHM choroideremia (Rab escort protein 1)
COQ3 coenzyme Q3 methyltransferase
CROT carnitine O-octanoyltransferase
DNAL4 dynein, axonemal, light chain 4
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
ECM1 extracellular matrix protein 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM179B family with sequence similarity 179, member B
FAM63A family with sequence similarity 63, member A
FES FES proto-oncogene, tyrosine kinase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPR18 G protein-coupled receptor 18
GPR85 G protein-coupled receptor 85
GTF2I general transcription factor IIi
HCAR3 hydroxycarboxylic acid receptor 3
HHLA3 HERV-H LTR-associating 3
HIST1H2AE histone cluster 1, H2ae
HIST1H2AJ histone cluster 1, H2aj
IFT46 intraflagellar transport 46
IL2 interleukin 2
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
JMJD4 jumonji domain containing 4
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCTD15 potassium channel tetramerization domain containing 15
KDM7A lysine (K)-specific demethylase 7A
KLHL28 kelch-like family member 28
KPTN kaptin (actin binding protein)
KRT20 keratin 20, type I
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIME1 Lck interacting transmembrane adaptor 1
LINS lines homolog (Drosophila)
LNPEP leucyl/cystinyl aminopeptidase
LOC100287590 uncharacterized LOC100287590
LY6D lymphocyte antigen 6 complex, locus D
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MBNL3 muscleblind-like splicing regulator 3
METTL16 methyltransferase like 16
MOCOS molybdenum cofactor sulfurase
MRAS muscle RAS oncogene homolog
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
PBOV1 prostate and breast cancer overexpressed 1
PDE12 phosphodiesterase 12
PGM3 phosphoglucomutase 3
PIP prolactin-induced protein
PIR pirin (iron-binding nuclear protein)
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PKD2L2 polycystic kidney disease 2-like 2
PPIEL peptidylprolyl isomerase E-like pseudogene
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RHOBTB2 Rho-related BTB domain containing 2
RRP9 ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8
SIRT6 sirtuin 6
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC16A6 solute carrier family 16, member 6
SPATA2L spermatogenesis associated 2-like
SPATA7 spermatogenesis associated 7
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TESC tescalcin
TIGD6 tigger transposable element derived 6
TMEM209 transmembrane protein 209
TRAPPC13 trafficking protein particle complex 13
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPYL2 TSPY-like 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR19 WD repeat domain 19
WRAP73 WD repeat containing, antisense to TP73
ZC2HC1A zinc finger, C2HC-type containing 1A
ZFP30 ZFP30 zinc finger protein
ZNF345 zinc finger protein 345
ZNF813 zinc finger protein 813
ZNF862 zinc finger protein 862