basophilic leukemia cell Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A rare type of leukemia in which basophils predominate; both acute and chronic varieties have been observed. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004286)
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Genes

291 proteins co-occuring with the tissue basophilic leukemia cell in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
SYK spleen tyrosine kinase 1.50386
SYT3 synaptotagmin III 1.40524
LAT2 linker for activation of T cells family, member 2 1.37636
LYN LYN proto-oncogene, Src family tyrosine kinase 1.35677
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.32325
PLCG1 phospholipase C, gamma 1 1.29939
ALOX5 arachidonate 5-lipoxygenase 1.26934
LAT linker for activation of T cells 1.20467
SYT2 synaptotagmin II 1.198
CD300LF CD300 molecule-like family member f 1.16959
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 1.1235
CD300E CD300e molecule 1.09341
RBL2 retinoblastoma-like 2 1.05017
HDC histidine decarboxylase 1.01243
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 1.00763
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 1.00022
THY1 Thy-1 cell surface antigen 0.961607
STIM2 stromal interaction molecule 2 0.945226
TREML1 triggering receptor expressed on myeloid cells-like 1 0.933195
OR1J1 olfactory receptor, family 1, subfamily J, member 1 0.931479
DEFB106B defensin, beta 106B 0.927621
RBL1 retinoblastoma-like 1 0.901254
LTC4S leukotriene C4 synthase 0.890525
PLA2G1B phospholipase A2, group IB (pancreas) 0.884591
RASA3 RAS p21 protein activator 3 0.883744
LGALS3 lectin, galactoside-binding, soluble, 3 0.881627
GLRX3 glutaredoxin 3 0.857153
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.844965
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.842447
CETN1 centrin, EF-hand protein, 1 0.836575
STX3 syntaxin 3 0.812309
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.802293
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.793959
LTA4H leukotriene A4 hydrolase 0.777325
CD63 CD63 molecule 0.752057
TRIO trio Rho guanine nucleotide exchange factor 0.744214
C3AR1 complement component 3a receptor 1 0.739678
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.729385
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.724453
GGT6 gamma-glutamyltransferase 6 0.698216
CPA3 carboxypeptidase A3 (mast cell) 0.694128
GGTLC1 gamma-glutamyltransferase light chain 1 0.693311
TRPM7 transient receptor potential cation channel, subfamily M, member 7 0.692493
GGT5 gamma-glutamyltransferase 5 0.681064
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.67984
GGT7 gamma-glutamyltransferase 7 0.677803
SIGLEC9 sialic acid binding Ig-like lectin 9 0.659897
STXBP2 syntaxin binding protein 2 0.658678
PLSCR1 phospholipid scramblase 1 0.649749
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.641238
LPO lactoperoxidase 0.640023
LTB4R leukotriene B4 receptor 0.640023
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.63638
LILRP1 leukocyte immunoglobulin-like receptor pseudogene 1 0.625061
SIGLEC14 sialic acid binding Ig-like lectin 14 0.621428
TSPAN1 tetraspanin 1 0.619007
ORAI1 ORAI calcium release-activated calcium modulator 1 0.613764
RB1 retinoblastoma 1 0.579817
CERK ceramide kinase 0.576415
HDAC3 histone deacetylase 3 0.574416
TELO2 telomere maintenance 2 0.571219
FPR1 formyl peptide receptor 1 0.568823
ALB albumin 0.562042
RBSN rabenosyn, RAB effector 0.547326
RGS1 regulator of G-protein signaling 1 0.535042
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.533856
PIAS3 protein inhibitor of activated STAT, 3 0.533856
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.525955
C5AR2 complement component 5a receptor 2 0.523982
PXN paxillin 0.521223
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.521223
EZR ezrin 0.516497
CD247 CD247 molecule 0.507457
GSS glutathione synthetase 0.498832
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 0.494136
RIOK3 RIO kinase 3 0.478145
FAAH fatty acid amide hydrolase 0.471151
E2F5 E2F transcription factor 5, p130-binding 0.460982
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.45567
LIN52 lin-52 DREAM MuvB core complex component 0.454512
LIN37 lin-37 DREAM MuvB core complex component 0.449308
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.447384
TRPM6 transient receptor potential cation channel, subfamily M, member 6 0.445653
PRF1 perforin 1 (pore forming protein) 0.439123
CD53 CD53 molecule 0.432225
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.431843
E2F6 E2F transcription factor 6 0.427063
LIN54 lin-54 DREAM MuvB core complex component 0.422768
E2F4 E2F transcription factor 4, p107/p130-binding 0.420766
TRPM4 transient receptor potential cation channel, subfamily M, member 4 0.420004
MSN moesin 0.412771
TRIM71 tripartite motif containing 71, E3 ubiquitin protein ligase 0.411251
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.409731
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.409351
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.408212
ADORA3 adenosine A3 receptor 0.407073
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.390799
ANXA2 annexin A2 0.389289
E2F3 E2F transcription factor 3 0.387404
DNAH8 dynein, axonemal, heavy chain 8 0.382508
ANXA1 annexin A1 0.381755
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 0.371432
SPN sialophorin 0.359292
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.352598
GAB2 GRB2-associated binding protein 2 0.351114
GRB2 growth factor receptor-bound protein 2 0.350372
GPX5 glutathione peroxidase 5 0.350001
GPX4 glutathione peroxidase 4 0.346298
MYLK myosin light chain kinase 0.342971
FN1 fibronectin 1 0.340757
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.339835
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) 0.33919
EMP1 epithelial membrane protein 1 0.33744
TFDP1 transcription factor Dp-1 0.336612
TDH L-threonine dehydrogenase (pseudogene) 0.3356
GPX1 glutathione peroxidase 1 0.335233
STX4 syntaxin 4 0.334865
CCL1 chemokine (C-C motif) ligand 1 0.333763
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 0.328811
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) 0.326981
CTSG cathepsin G 0.326067
HINFP histone H4 transcription factor 0.324879
PLBD2 phospholipase B domain containing 2 0.314227
PDC phosducin 0.310783
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.310059
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 0.307799
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.306805
RNF43 ring finger protein 43 0.306534
MAP2K2 mitogen-activated protein kinase kinase 2 0.303919
C12ORF4 chromosome 12 open reading frame 4 0.303829
TBX21 T-box 21 0.30032
ANK1 ankyrin 1, erythrocytic 0.299242
EN2 engrailed homeobox 2 0.298883
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.298165
RAB3D RAB3D, member RAS oncogene family 0.296372
MGAM maltase-glucoamylase 0.292079
PIF1 PIF1 5'-to-3' DNA helicase 0.288336
TAC1 tachykinin, precursor 1 0.286026
NPAT nuclear protein, ataxia-telangiectasia locus 0.278603
TUBB2A tubulin, beta 2A class IIa 0.272475
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.2723
LIN9 lin-9 DREAM MuvB core complex component 0.271517
C4A complement component 4A (Rodgers blood group) 0.268828
SUCLG1 succinate-CoA ligase, alpha subunit 0.267015
LGALS1 lectin, galactoside-binding, soluble, 1 0.266413
GP6 glycoprotein VI (platelet) 0.266413
CPLX2 complexin 2 0.263327
FAM195A family with sequence similarity 195, member A 0.262645
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.261539
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.258243
UNC13D unc-13 homolog D (C. elegans) 0.258075
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.257824
IL1RN interleukin 1 receptor antagonist 0.252261
SYT1 synaptotagmin I 0.251279
TUBB tubulin, beta class I 0.249815
GAGE1 G antigen 1 0.245491
TYROBP TYRO protein tyrosine kinase binding protein 0.243294
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.238706
CCL2 chemokine (C-C motif) ligand 2 0.238406
GPR135 G protein-coupled receptor 135 0.238182
PARP1 poly (ADP-ribose) polymerase 1 0.238108
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.234878
LOX lysyl oxidase 0.232881
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.230656
FPR3 formyl peptide receptor 3 0.229907
RBBP4 retinoblastoma binding protein 4 0.229839
CCNC cyclin C 0.227315
MDM4 MDM4, p53 regulator 0.223723
STIM1 stromal interaction molecule 1 0.222224
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.222107
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.221521
BMF Bcl2 modifying factor 0.221176
FABP5 fatty acid binding protein 5 (psoriasis-associated) 0.220946
VAV1 vav 1 guanine nucleotide exchange factor 0.220831
CCNG2 cyclin G2 0.217974
SIN3A SIN3 transcription regulator family member A 0.21673
TXN thioredoxin 0.215928
COL5A1 collagen, type V, alpha 1 0.215534
GAGE12I G antigen 12I 0.212761
PRMT5 protein arginine methyltransferase 5 0.208955
XAF1 XIAP associated factor 1 0.208884
PRKCA protein kinase C, alpha 0.206009
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.20551
NIPSNAP3B nipsnap homolog 3B (C. elegans) 0.204728
G6PC2 glucose-6-phosphatase, catalytic, 2 0.204336
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) 0.203984
CCNE2 cyclin E2 0.203346
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.203179
PTAFR platelet-activating factor receptor 0.202275
ALOX15 arachidonate 15-lipoxygenase 0.202046
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.201234
C5AR1 complement component 5a receptor 1 0.200656
UGP2 UDP-glucose pyrophosphorylase 2 0.200193
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.199318
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.199
PDGFD platelet derived growth factor D 0.198786
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.198742
HIST1H4D histone cluster 1, H4d 0.198628
HIST1H4J histone cluster 1, H4j 0.198628
HIST1H4B histone cluster 1, H4b 0.198628
HIST1H4I histone cluster 1, H4i 0.198628
HIST1H4H histone cluster 1, H4h 0.198628
HIST1H4F histone cluster 1, H4f 0.198628
HIST1H4E histone cluster 1, H4e 0.198628
HIST1H4C histone cluster 1, H4c 0.198628
HIST1H4A histone cluster 1, H4a 0.198628
HIST1H4K histone cluster 1, H4k 0.198628
HIST2H4B histone cluster 2, H4b 0.198628
HIST2H4A histone cluster 2, H4a 0.198614
HIST1H4L histone cluster 1, H4l 0.198572
HIST4H4 histone cluster 4, H4 0.198566
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.198504
CDK6 cyclin-dependent kinase 6 0.198361
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.198316
TP73 tumor protein p73 0.198223
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.198162
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.197819
MOGS mannosyl-oligosaccharide glucosidase 0.197647
SNAI2 snail family zinc finger 2 0.197564
STMN1 stathmin 1 0.197349
EP300 E1A binding protein p300 0.197264
ARRB2 arrestin, beta 2 0.197111
ACD adrenocortical dysplasia homolog (mouse) 0.196806
ADRBK1 adrenergic, beta, receptor kinase 1 0.196752
DAPK1 death-associated protein kinase 1 0.196658
MYH9 myosin, heavy chain 9, non-muscle 0.196609
SNAP23 synaptosomal-associated protein, 23kDa 0.196545
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.196355
SRGN serglycin 0.196289
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.195822
GFI1 growth factor independent 1 transcription repressor 0.195672
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.195541
CLDN11 claudin 11 0.195208
ELANE elastase, neutrophil expressed 0.194957
WEE1 WEE1 G2 checkpoint kinase 0.194697
PRTN3 proteinase 3 0.194629
CCNE1 cyclin E1 0.194209
IDUA iduronidase, alpha-L- 0.194144
MIR17 microRNA 17 0.194018
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.193991
IL32 interleukin 32 0.193835
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5 0.19376
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.193473
POU5F1B POU class 5 homeobox 1B 0.193459
HMGA1 high mobility group AT-hook 1 0.193139
AZU1 azurocidin 1 0.192945
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.192457
NME3 NME/NM23 nucleoside diphosphate kinase 3 0.191722
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.191714
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.188717
SOS1 son of sevenless homolog 1 (Drosophila) 0.188683
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.18866
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.188301
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.188062
ARRB1 arrestin, beta 1 0.187844
TLR8 toll-like receptor 8 0.187596
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.18691
NSF N-ethylmaleimide-sensitive factor 0.186351
CA10 carbonic anhydrase X 0.185328
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.184797
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.184275
NME2 NME/NM23 nucleoside diphosphate kinase 2 0.184208
CXCR1 chemokine (C-X-C motif) receptor 1 0.183322
TLR1 toll-like receptor 1 0.182863
P2RY14 purinergic receptor P2Y, G-protein coupled, 14 0.181296
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) 0.179368
IL13 interleukin 13 0.17833
CMA1 chymase 1, mast cell 0.178304
ZHX2 zinc fingers and homeoboxes 2 0.177686
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.177182
SOCS2 suppressor of cytokine signaling 2 0.176425
FPR2 formyl peptide receptor 2 0.175751
CIITA class II, major histocompatibility complex, transactivator 0.174583
POU5F1 POU class 5 homeobox 1 0.174481
FHIT fragile histidine triad 0.174278
KIAA0101 KIAA0101 0.173611
TPH1 tryptophan hydroxylase 1 0.17336
KITLG KIT ligand 0.172882
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.172695
GPC3 glypican 3 0.171606
HDAC2 histone deacetylase 2 0.171403
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.170534
IL5 interleukin 5 0.169973
EVPL envoplakin 0.169752
FYN FYN proto-oncogene, Src family tyrosine kinase 0.169618
CDK2 cyclin-dependent kinase 2 0.168985
TACR1 tachykinin receptor 1 0.168847
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.168425
TP53 tumor protein p53 0.168378
MMP10 matrix metallopeptidase 10 0.168378
MBTPS1 membrane-bound transcription factor peptidase, site 1 0.1679