base-excision repair Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. (Gene Ontology, GO_0006284)
External Link http://amigo.geneontology.org/amigo/term/GO:0006284
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Genes

39 genes participating in the base-excision repair biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
CCNO cyclin O
DNA2 DNA replication helicase/nuclease 2
ERCC6 excision repair cross-complementation group 6
FEN1 flap structure-specific endonuclease 1
HMGA2 high mobility group AT-hook 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
LIG1 ligase I, DNA, ATP-dependent
LIG3 ligase III, DNA, ATP-dependent
MBD4 methyl-CpG binding domain protein 4
MPG N-methylpurine-DNA glycosylase
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MUTYH mutY homolog
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NEIL2 nei endonuclease VIII-like 2 (E. coli)
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NTHL1 nth endonuclease III-like 1 (E. coli)
OGG1 8-oxoguanine DNA glycosylase
PARP1 poly (ADP-ribose) polymerase 1
PARP2 poly (ADP-ribose) polymerase 2
PCNA proliferating cell nuclear antigen
POLB polymerase (DNA directed), beta
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLD2 polymerase (DNA directed), delta 2, accessory subunit
POLD3 polymerase (DNA-directed), delta 3, accessory subunit
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
POLQ polymerase (DNA directed), theta
PRMT6 protein arginine methyltransferase 6
RPA1 replication protein A1, 70kDa
RPA2 replication protein A2, 32kDa
RPA3 replication protein A3, 14kDa
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
TDG thymine-DNA glycosylase
TP53 tumor protein p53
UNG uracil-DNA glycosylase
USP47 ubiquitin specific peptidase 47
WRN Werner syndrome, RecQ helicase-like
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1