basal lamina Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix. (Gene Ontology, GO_0005605)
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Genes

317 proteins co-occuring with the basal lamina cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
LAMB2 laminin, beta 2 (laminin S) 2.66825
COL7A1 collagen, type VII, alpha 1 2.3577
LAMB3 laminin, beta 3 2.34081
FN1 fibronectin 1 2.25125
NID1 nidogen 1 2.24284
LAMC2 laminin, gamma 2 2.10201
COL17A1 collagen, type XVII, alpha 1 2.0012
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 1.77339
LAMA2 laminin, alpha 2 1.73247
RARA retinoic acid receptor, alpha 1.71187
CD44 CD44 molecule (Indian blood group) 1.61882
ACHE acetylcholinesterase (Yt blood group) 1.61706
ITGA6 integrin, alpha 6 1.5367
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 1.52541
TNC tenascin C 1.52089
LAMA4 laminin, alpha 4 1.44629
MMP9 matrix metallopeptidase 9 1.44064
MMP2 matrix metallopeptidase 2 1.42204
LAMA3 laminin, alpha 3 1.34229
CD79A CD79a molecule, immunoglobulin-associated alpha 1.30658
LAMA5 laminin, alpha 5 1.28623
PHYH phytanoyl-CoA 2-hydroxylase 1.27133
ITGB4 integrin, beta 4 1.26604
LAMA1 laminin, alpha 1 1.23088
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 1.20138
NID2 nidogen 2 (osteonidogen) 1.18492
DMD dystrophin 1.18235
MUSK muscle, skeletal, receptor tyrosine kinase 1.12092
FTH1 ferritin, heavy polypeptide 1 1.05236
FTL ferritin, light polypeptide 1.04733
ITGA7 integrin, alpha 7 1.03129
SDC2 syndecan 2 1.02032
PAX7 paired box 7 1.01833
F8 coagulation factor VIII, procoagulant component 0.970331
AMTN amelotin 0.96792
MMP7 matrix metallopeptidase 7 0.953528
FBLN1 fibulin 1 0.942584
FBLN2 fibulin 2 0.937377
SEBOX SEBOX homeobox 0.928422
FKTN fukutin 0.923259
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.916243
RAPSN receptor-associated protein of the synapse 0.906926
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.90646
BCAM basal cell adhesion molecule (Lutheran blood group) 0.896257
UTRN utrophin 0.883782
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.882399
B3GAT1 beta-1,3-glucuronyltransferase 1 0.869046
LAMB1 laminin, beta 1 0.842401
KRT14 keratin 14, type I 0.840564
ODAM odontogenic, ameloblast asssociated 0.83781
MMP1 matrix metallopeptidase 1 0.814864
TGFB1 transforming growth factor, beta 1 0.809817
CD151 CD151 molecule (Raph blood group) 0.806606
CD34 CD34 molecule 0.802938
MMP3 matrix metallopeptidase 3 0.791939
DOK7 docking protein 7 0.786444
FGF2 fibroblast growth factor 2 (basic) 0.780954
ALB albumin 0.764527
IVL involucrin 0.761797
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.761797
FRAS1 Fraser extracellular matrix complex subunit 1 0.75181
BCHE butyrylcholinesterase 0.745477
PRIMA1 proline rich membrane anchor 1 0.74322
TIMP2 TIMP metallopeptidase inhibitor 2 0.740965
GFAP glial fibrillary acidic protein 0.740064
RPSA ribosomal protein SA 0.735565
LGALS3 lectin, galactoside-binding, soluble, 3 0.733319
FBN1 fibrillin 1 0.724812
TIMP1 TIMP metallopeptidase inhibitor 1 0.706156
PRX periaxin 0.705714
FLG filaggrin 0.703067
PLAT plasminogen activator, tissue 0.700863
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 0.700423
FREM3 FRAS1 related extracellular matrix 3 0.690326
MET MET proto-oncogene, receptor tyrosine kinase 0.68508
FREM1 FRAS1 related extracellular matrix 1 0.677238
FGF1 fibroblast growth factor 1 (acidic) 0.665096
ENO2 enolase 2 (gamma, neuronal) 0.663368
NOTCH3 notch 3 0.656033
MMP10 matrix metallopeptidase 10 0.646574
MYOD1 myogenic differentiation 1 0.644429
VCAN versican 0.641001
ECM1 extracellular matrix protein 1 0.63715
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.632451
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 0.621804
ITGA1 integrin, alpha 1 0.621379
BMP1 bone morphogenetic protein 1 0.619255
MAG myelin associated glycoprotein 0.617557
WARS tryptophanyl-tRNA synthetase 0.615013
MMP19 matrix metallopeptidase 19 0.610778
COL4A1 collagen, type IV, alpha 1 0.609509
GFPT1 glutamine--fructose-6-phosphate transaminase 1 0.609086
OCLN occludin 0.606128
EGFR epidermal growth factor receptor 0.602752
NCAM1 neural cell adhesion molecule 1 0.599381
POMT1 protein-O-mannosyltransferase 1 0.594753
NOTCH4 notch 4 0.589714
RFXANK regulatory factor X-associated ankyrin-containing protein 0.587618
KRT5 keratin 5, type II 0.585105
TSPAN18 tetraspanin 18 0.575912
THAP2 THAP domain containing, apoptosis associated protein 2 0.575912
KRT10 keratin 10, type I 0.572578
HBA1 hemoglobin, alpha 1 0.571745
PLG plasminogen 0.570496
HBA2 hemoglobin, alpha 2 0.565508
PMP22 peripheral myelin protein 22 0.564262
FREM2 FRAS1 related extracellular matrix protein 2 0.551425
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.546472
PLAU plasminogen activator, urokinase 0.542352
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 0.539883
AGRN agrin 0.53906
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.535772
UBL7 ubiquitin-like 7 0.525931
ALPPL2 alkaline phosphatase, placental-like 2 0.523476
TJP1 tight junction protein 1 0.523476
ACPP acid phosphatase, prostate 0.522659
ALPP alkaline phosphatase, placental 0.522659
ALPL alkaline phosphatase, liver/bone/kidney 0.522659
PXN paxillin 0.519798
VEGFA vascular endothelial growth factor A 0.518165
MYF5 myogenic factor 5 0.5149
DCN decorin 0.497826
ITGB8 integrin, beta 8 0.49742
VCL vinculin 0.497015
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.49661
FGF7 fibroblast growth factor 7 0.495395
COL4A5 collagen, type IV, alpha 5 0.492561
VWF von Willebrand factor 0.487307
AMELX amelogenin, X-linked 0.486096
NGF nerve growth factor (beta polypeptide) 0.482467
QRICH1 glutamine-rich 1 0.482064
AQP4 aquaporin 4 0.480453
AMELY amelogenin, Y-linked 0.479245
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.478038
OCIAD1 OCIA domain containing 1 0.474822
DST dystonin 0.47442
RICTOR RPTOR independent companion of MTOR, complex 2 0.473215
CLDN11 claudin 11 0.472412
ERBB2 erb-b2 receptor tyrosine kinase 2 0.472011
GJA1 gap junction protein, alpha 1, 43kDa 0.471208
MMP8 matrix metallopeptidase 8 0.462798
IL1B interleukin 1, beta 0.459602
SDC1 syndecan 1 0.441708
DSG1 desmoglein 1 0.438937
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.437356
CLDN5 claudin 5 0.43617
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.43538
DHH desert hedgehog 0.430647
MYOG myogenin (myogenic factor 4) 0.427891
INS insulin 0.426318
SYP synaptophysin 0.42082
NTN1 netrin 1 0.41612
PCNA proliferating cell nuclear antigen 0.413382
CD9 CD9 molecule 0.412992
DSP desmoplakin 0.401304
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.401304
KRT3 keratin 3, type II 0.400139
MRPS21 mitochondrial ribosomal protein S21 0.394323
MED10 mediator complex subunit 10 0.392001
FEZF1 FEZ family zinc finger 1 0.387751
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.382354
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.381584
DSG3 desmoglein 3 0.380429
GALC galactosylceramidase 0.379276
KRT13 keratin 13, type I 0.375818
MMP13 matrix metallopeptidase 13 0.370067
EDA ectodysplasin A 0.370067
DSC1 desmocollin 1 0.370067
TP53 tumor protein p53 0.370067
KRT1 keratin 1, type II 0.368919
SDC4 syndecan 4 0.368536
ITGB7 integrin, beta 7 0.367388
ITGB6 integrin, beta 6 0.366241
CHAT choline O-acetyltransferase 0.362804
HPSE heparanase 0.362804
FDCSP follicular dendritic cell secreted protein 0.360515
IGF1 insulin-like growth factor 1 (somatomedin C) 0.355563
CALCA calcitonin-related polypeptide alpha 0.34645
THBS1 thrombospondin 1 0.344935
TLL1 tolloid-like 1 0.341907
CSN2 casein beta 0.340395
ANGPT2 angiopoietin 2 0.333602
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.329084
BCAN brevican 0.327205
TIMP3 TIMP metallopeptidase inhibitor 3 0.325327
PTTG1IP pituitary tumor-transforming 1 interacting protein 0.32345
GPC1 glypican 1 0.323075
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.316334
FKRP fukutin related protein 0.315212
MAMDC4 MAM domain containing 4 0.313344
COL6A2 collagen, type VI, alpha 2 0.305888
ICAM1 intercellular adhesion molecule 1 0.302168
KRT8 keratin 8, type II 0.301054
ERBB3 erb-b2 receptor tyrosine kinase 3 0.300682
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.29994
TF transferrin 0.299569
MPZ myelin protein zero 0.299197
MMP26 matrix metallopeptidase 26 0.297342
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.294748
TG thyroglobulin 0.294748
CCM2 cerebral cavernous malformation 2 0.294378
AMBN ameloblastin (enamel matrix protein) 0.294007
SHH sonic hedgehog 0.294007
PKP1 plakophilin 1 0.293637
CTGF connective tissue growth factor 0.293637
BLCAP bladder cancer associated protein 0.293267
KRT12 keratin 12, type I 0.292157
NRG1 neuregulin 1 0.291787
NGFR nerve growth factor receptor 0.285138
BGN biglycan 0.282558
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.281821
PPY pancreatic polypeptide 0.280349
LAD1 ladinin 1 0.276671
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1 0.273367
COL4A2 collagen, type IV, alpha 2 0.2719
SOX10 SRY (sex determining region Y)-box 10 0.267871
TMSB4X thymosin beta 4, X-linked 0.265677
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.264215
CTSF cathepsin F 0.264215
KRT4 keratin 4, type II 0.26312
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.262755
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.26239
EPSTI1 epithelial stromal interaction 1 (breast) 0.258016
SAG S-antigen; retina and pineal gland (arrestin) 0.257652
COL18A1 collagen, type XVIII, alpha 1 0.256561
MMP12 matrix metallopeptidase 12 0.254743
DYSF dysferlin 0.254017
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.254017
CHRD chordin 0.252202
KRT20 keratin 20, type I 0.251114
LACRT lacritin 0.250751
FSCN3 fascin actin-bundling protein 3, testicular 0.246407
ZNF354B zinc finger protein 354B 0.244601
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.243158
LOX lysyl oxidase 0.240636
COL8A1 collagen, type VIII, alpha 1 0.238478
FSCN1 fascin actin-bundling protein 1 0.238478
GNPDA1 glucosamine-6-phosphate deaminase 1 0.238119
NES nestin 0.237401
TLL2 tolloid-like 2 0.236324
FSCN2 fascin actin-bundling protein 2, retinal 0.233459
FRMD3 FERM domain containing 3 0.230601
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.229532
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.228819
LYZ lysozyme 0.228464
CDH5 cadherin 5, type 2 (vascular endothelium) 0.228464
VEGFC vascular endothelial growth factor C 0.224913
CD81 CD81 molecule 0.223497
CD68 CD68 molecule 0.221025
FBN2 fibrillin 2 0.220673
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.219617
CDC42 cell division cycle 42 0.218563
LGALS7B lectin, galactoside-binding, soluble, 7B 0.21716
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.21646
MB myoglobin 0.215761
CSN1S1 casein alpha s1 0.211933
ELANE elastase, neutrophil expressed 0.210549
ZNF675 zinc finger protein 675 0.210203
JUN jun proto-oncogene 0.209858
PLXDC1 plexin domain containing 1 0.206423
TNF tumor necrosis factor 0.20574
DNAH8 dynein, axonemal, heavy chain 8 0.205399
SALL2 spalt-like transcription factor 2 0.205399
KRT19 keratin 19, type I 0.202346
TAC1 tachykinin, precursor 1 0.194698
ELN elastin 0.194371
KDR kinase insert domain receptor 0.194045
CNTN6 contactin 6 0.193394
ITGAV integrin, alpha V 0.190814
EBAG9 estrogen receptor binding site associated, antigen, 9 0.190814
MEGF10 multiple EGF-like-domains 10 0.18859
EMCN endomucin 0.18796
NCAN neurocan 0.187333
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase 0.18702
GLB1 galactosidase, beta 1 0.186087
ANGPT1 angiopoietin 1 0.184853
FGF3 fibroblast growth factor 3 0.183935
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.183935
CXCL12 chemokine (C-X-C motif) ligand 12 0.183025
SOX17 SRY (sex determining region Y)-box 17 0.182422
FAP fibroblast activation protein, alpha 0.179752
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.179167
RTN4RL2 reticulon 4 receptor-like 2 0.177439
PBK PDZ binding kinase 0.17687
TH tyrosine hydroxylase 0.175466
VCAM1 vascular cell adhesion molecule 1 0.174911
HES5 hes family bHLH transcription factor 5 0.174635
SOX8 SRY (sex determining region Y)-box 8 0.173543
CCL21 chemokine (C-C motif) ligand 21 0.173543
PRAMEF12 PRAME family member 12 0.173003
MED28 mediator complex subunit 28 0.171673
SPON2 spondin 2, extracellular matrix protein 0.170888
FYN FYN proto-oncogene, Src family tyrosine kinase 0.170114
FST follistatin 0.170114
SCPEP1 serine carboxypeptidase 1 0.169604
CHGA chromogranin A 0.16935
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.169099
SFN stratifin 0.168847
PRRC2A proline-rich coiled-coil 2A 0.168598
LYPD3 LY6/PLAUR domain containing 3 0.167366
POU6F2 POU class 6 homeobox 2 0.167125
DNM2 dynamin 2 0.166405
CCL19 chemokine (C-C motif) ligand 19 0.165932
REG3A regenerating islet-derived 3 alpha 0.165932
GATA6 GATA binding protein 6 0.164315
RUNX2 runt-related transcription factor 2 0.162763
CLCN2 chloride channel, voltage-sensitive 2 0.162117
BMF Bcl2 modifying factor 0.161693
KRT7 keratin 7, type II 0.161484
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.161275
AQP5 aquaporin 5 0.160863
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 0.160863
MIR100 microRNA 100 0.160053
CST3 cystatin C 0.158502
HMCN1 hemicentin 1 0.158315
SNTA1 syntrophin, alpha 1 0.157039
CLDN1 claudin 1 0.156342