basal forebrain Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The basal forebrain is a term for a group of structures that lie near the bottom of the front of the brain, including the nucleus basalis, diagonal band, medial septum and substantia innominata. These structures are important in the production of a brain chemical called acetylcholine, which is then distributed widely throughout the brain. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002444)
Similar Terms
Downloads & Tools

Genes

335 proteins co-occuring with the tissue basal forebrain in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CHAT choline O-acetyltransferase 3.72201
NGF nerve growth factor (beta polypeptide) 2.98496
ACHE acetylcholinesterase (Yt blood group) 2.6756
NGFR nerve growth factor receptor 2.5102
PVALB parvalbumin 2.04819
GAL galanin/GMAP prepropeptide 2.00918
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.88581
FOS FBJ murine osteosarcoma viral oncogene homolog 1.8399
BDNF brain-derived neurotrophic factor 1.82708
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 1.79245
HCRT hypocretin (orexin) neuropeptide precursor 1.70893
CALB1 calbindin 1, 28kDa 1.67656
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.65307
BCHE butyrylcholinesterase 1.56867
TH tyrosine hydroxylase 1.51997
NTF3 neurotrophin 3 1.49585
NPY neuropeptide Y 1.47288
NTS neurotensin 1.408
PEBP1 phosphatidylethanolamine binding protein 1 1.39284
CALB2 calbindin 2 1.3759
TAC1 tachykinin, precursor 1 1.35268
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 1.35177
SST somatostatin 1.35041
NPS neuropeptide S 1.33907
CRH corticotropin releasing hormone 1.27695
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.25592
NTF4 neurotrophin 4 1.19623
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 1.18823
PTGDS prostaglandin D2 synthase 21kDa (brain) 1.18423
TECTA tectorin alpha 1.12704
LHX8 LIM homeobox 8 1.12084
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 1.10093
CA4 carbonic anhydrase IV 1.09606
CHRM1 cholinergic receptor, muscarinic 1 1.03873
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.999344
CNTF ciliary neurotrophic factor 0.985859
PSEN1 presenilin 1 0.984556
SDF4 stromal cell derived factor 4 0.980217
MAPT microtubule-associated protein tau 0.975882
TRH thyrotropin-releasing hormone 0.972417
ZCCHC12 zinc finger, CCHC domain containing 12 0.943075
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.934911
ESR1 estrogen receptor 1 0.932337
POMC proopiomelanocortin 0.926336
PORCN porcupine homolog (Drosophila) 0.925907
OPRM1 opioid receptor, mu 1 0.922483
GALR2 galanin receptor 2 0.891798
CA13 carbonic anhydrase XIII 0.889253
PMEL premelanosome protein 0.873594
PNMT phenylethanolamine N-methyltransferase 0.855891
CCK cholecystokinin 0.842027
PENK proenkephalin 0.836575
GALR1 galanin receptor 1 0.836156
CHRM2 cholinergic receptor, muscarinic 2 0.832804
SAMD1 sterile alpha motif domain containing 1 0.826523
GALR3 galanin receptor 3 0.806465
APP amyloid beta (A4) precursor protein 0.804378
GDF2 growth differentiation factor 2 0.799375
OXT oxytocin/neurophysin I prepropeptide 0.79146
ADORA1 adenosine A1 receptor 0.790212
APOE apolipoprotein E 0.784804
RELN reelin 0.775664
PDYN prodynorphin 0.773174
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.7711
CRHR1 corticotropin releasing hormone receptor 1 0.754537
MEA1 male-enhanced antigen 1 0.742976
GDNF glial cell derived neurotrophic factor 0.742564
GPR62 G protein-coupled receptor 62 0.74174
AVP arginine vasopressin 0.736382
RLN3 relaxin 3 0.735559
NRSN2 neurensin 2 0.724863
ESR2 estrogen receptor 2 (ER beta) 0.71542
NKX2-1 NK2 homeobox 1 0.7105
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.697399
DRD2 dopamine receptor D2 0.693311
GFAP glial fibrillary acidic protein 0.685959
FAM193A family with sequence similarity 193, member A 0.682287
ADORA2A adenosine A2a receptor 0.679025
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like 0.664775
LHX6 LIM homeobox 6 0.661929
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.637594
TACR3 tachykinin receptor 3 0.630718
NVL nuclear VCP-like 0.628697
FGF2 fibroblast growth factor 2 (basic) 0.626273
SYP synaptophysin 0.599675
GPR82 G protein-coupled receptor 82 0.586026
OXTR oxytocin receptor 0.563637
DLX1 distal-less homeobox 1 0.556865
NPFF neuropeptide FF-amide peptide precursor 0.556467
LSAMP limbic system-associated membrane protein 0.552888
NPFFR2 neuropeptide FF receptor 2 0.550106
NES nestin 0.546136
GPR63 G protein-coupled receptor 63 0.535833
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 0.535042
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 0.53346
GPR61 G protein-coupled receptor 61 0.53346
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.528719
VAX1 ventral anterior homeobox 1 0.525955
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.525955
SCGN secretagogin, EF-hand calcium binding protein 0.519647
SORT1 sortilin 1 0.51571
NTSR2 neurotensin receptor 2 0.510992
GLG1 golgi glycoprotein 1 0.505887
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.503926
PTPRF protein tyrosine phosphatase, receptor type, F 0.503533
GAP43 growth associated protein 43 0.502357
CTXN2 cortexin 2 0.499223
INSRR insulin receptor-related receptor 0.489838
NTSR1 neurotensin receptor 1 (high affinity) 0.477756
BACE1 beta-site APP-cleaving enzyme 1 0.475812
CORT cortistatin 0.469987
LGI2 leucine-rich repeat LGI family, member 2 0.464174
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.459918
CDC37L1 cell division cycle 37-like 1 0.45567
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.450271
OLIG2 oligodendrocyte lineage transcription factor 2 0.448731
PTBP1 polypyrimidine tract binding protein 1 0.447576
GPR101 G protein-coupled receptor 101 0.447192
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.444884
SULT4A1 sulfotransferase family 4A, member 1 0.435672
MAP2 microtubule-associated protein 2 0.433757
GCSAM germinal center-associated, signaling and motility 0.43146
GLS glutaminase 0.426872
PRL prolactin 0.425344
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.424963
MNX1 motor neuron and pancreas homeobox 1 0.421148
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.420766
GLB1 galactosidase, beta 1 0.418861
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.409731
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.407073
SRPX2 sushi-repeat containing protein, X-linked 2 0.406315
JUN jun proto-oncogene 0.405935
TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 0.404418
CA1 carbonic anhydrase I 0.401765
MAOB monoamine oxidase B 0.397979
IAPP islet amyloid polypeptide 0.394197
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.394197
CREB1 cAMP responsive element binding protein 1 0.390799
CINP cyclin-dependent kinase 2 interacting protein 0.390799
IGKV1-17 immunoglobulin kappa variable 1-17 0.390044
GPR79 G protein-coupled receptor 79, pseudogene 0.387781
DPYSL2 dihydropyrimidinase-like 2 0.378748
TRHDE thyrotropin-releasing hormone degrading enzyme 0.375743
GLS2 glutaminase 2 (liver, mitochondrial) 0.374618
LGI4 leucine-rich repeat LGI family, member 4 0.371994
PSEN2 presenilin 2 0.371619
HCRTR1 hypocretin (orexin) receptor 1 0.369747
CA3 carbonic anhydrase III 0.367876
GHRH growth hormone releasing hormone 0.366007
TACR1 tachykinin receptor 1 0.364513
GPHN gephyrin 0.361527
PRIMA1 proline rich membrane anchor 1 0.354826
TSPO translocator protein (18kDa) 0.351114
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.34926
GALP galanin-like peptide 0.34926
LHB luteinizing hormone beta polypeptide 0.347038
GBX1 gastrulation brain homeobox 1 0.340019
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.334865
GRM7 glutamate receptor, metabotropic 7 0.333028
SHH sonic hedgehog 0.330827
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.329727
ENO2 enolase 2 (gamma, neuronal) 0.329727
PNOC prepronociceptin 0.323509
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.320956
AR androgen receptor 0.319134
FGF1 fibroblast growth factor 1 (acidic) 0.316588
ADRA2A adrenoceptor alpha 2A 0.315861
GPER1 G protein-coupled estrogen receptor 1 0.314772
GPR78 G protein-coupled receptor 78 0.307889
NTN1 netrin 1 0.306805
GPR45 G protein-coupled receptor 45 0.306083
PSENEN presenilin enhancer gamma secretase subunit 0.299242
CNR1 cannabinoid receptor 1 (brain) 0.298165
NPFFR1 neuropeptide FF receptor 1 0.29673
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.293866
LGI3 leucine-rich repeat LGI family, member 3 0.285316
AVPR1A arginine vasopressin receptor 1A 0.284962
VCX variable charge, X-linked 0.278251
PLB1 phospholipase B1 0.275094
VCX2 variable charge, X-linked 2 0.273696
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 0.269521
VCX3B variable charge, X-linked 3B 0.265381
TAC3 tachykinin 3 0.263327
CAPS calcyphosine 0.256568
DYNLRB1 dynein, light chain, roadblock-type 1 0.255567
VCX3A variable charge, X-linked 3A 0.25457
UTS2B urotensin 2B 0.251934
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.250301
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.243918
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.241746
CALCA calcitonin-related polypeptide alpha 0.241746
STX8 syntaxin 8 0.239007
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.235748
OPRL1 opiate receptor-like 1 0.232881
OXGR1 oxoglutarate (alpha-ketoglutarate) receptor 1 0.232881
DLX5 distal-less homeobox 5 0.232039
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.232039
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.230931
NPC1 Niemann-Pick disease, type C1 0.230656
TTC34 tetratricopeptide repeat domain 34 0.230382
MCHR2 melanin-concentrating hormone receptor 2 0.228497
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome 0.226411
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.225647
VIP vasoactive intestinal peptide 0.223662
ARX aristaless related homeobox 0.221989
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.221755
TPH1 tryptophan hydroxylase 1 0.221521
TFRC transferrin receptor 0.219485
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.218398
PRLHR prolactin releasing hormone receptor 0.217554
SATB1 SATB homeobox 1 0.217139
PRNP prion protein 0.216528
GYPE glycophorin E (MNS blood group) 0.215147
ADRA2C adrenoceptor alpha 2C 0.215147
GSK3B glycogen synthase kinase 3 beta 0.214388
OLIG1 oligodendrocyte transcription factor 1 0.213471
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.212413
NLGN2 neuroligin 2 0.198496
LHX5 LIM homeobox 5 0.190815
DLAT dihydrolipoamide S-acetyltransferase 0.189446
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 0.188074
HTN3 histatin 3 0.187864
TACR2 tachykinin receptor 2 0.187791
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.187757
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E 0.187034
CLEC3B C-type lectin domain family 3, member B 0.186677
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.185087
SCRT1 scratch family zinc finger 1 0.184512
PGLYRP3 peptidoglycan recognition protein 3 0.183816
LEMD3 LEM domain containing 3 0.183758
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase 0.183418
STAB2 stabilin 2 0.182832
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 0.182782
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1 0.182782
CHRM3 cholinergic receptor, muscarinic 3 0.182427
LHX1 LIM homeobox 1 0.182034
SYPL1 synaptophysin-like 1 0.181519
MSH4 mutS homolog 4 0.181168
NEU1 sialidase 1 (lysosomal sialidase) 0.180997
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1 0.180953
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.180513
NUCB2 nucleobindin 2 0.18015
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.179729
SIVA1 SIVA1, apoptosis-inducing factor 0.179392
NPSR1 neuropeptide S receptor 1 0.179196
NDEL1 nudE neurodevelopment protein 1-like 1 0.178728
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.17859
EGR1 early growth response 1 0.176465
UCN3 urocortin 3 0.176263
RHOD ras homolog family member D 0.175979
GYLTL1B glycosyltransferase-like 1B 0.174894
OR3A1 olfactory receptor, family 3, subfamily A, member 1 0.174828
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.174762
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 0.173825
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.172931
PRLH prolactin releasing hormone 0.172067
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.171988
PLLP plasmolipin 0.171936
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.1717
PTDSS2 phosphatidylserine synthase 2 0.171512
SLURP1 secreted LY6/PLAUR domain containing 1 0.171106
RAB3D RAB3D, member RAS oncogene family 0.170855
PALLD palladin, cytoskeletal associated protein 0.170827
SIX2 SIX homeobox 2 0.169856
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 0.169618
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.169321
MAOA monoamine oxidase A 0.169077
THUMPD1 THUMP domain containing 1 0.168046
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 0.167394
SPTA1 spectrin, alpha, erythrocytic 1 0.167361
LPP LIM domain containing preferred translocation partner in lipoma 0.166167
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 0.165993
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.165959
SNCB synuclein, beta 0.165637
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.165493
PTK7 protein tyrosine kinase 7 (inactive) 0.165349
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.165241
RANBP1 RAN binding protein 1 0.165241
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.164836
GLRA2 glycine receptor, alpha 2 0.164613
NOS1 nitric oxide synthase 1 (neuronal) 0.163031
ADRA1B adrenoceptor alpha 1B 0.162754
PLCB4 phospholipase C, beta 4 0.162018
PMCH pro-melanin-concentrating hormone 0.16018
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.160137
PCDH11Y protocadherin 11 Y-linked 0.160047
IPP intracisternal A particle-promoted polypeptide 0.159822
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.159007
FKTN fukutin 0.158961
PCDH11X protocadherin 11 X-linked 0.158497
ADRBK1 adrenergic, beta, receptor kinase 1 0.158358
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.158265
KISS1 KiSS-1 metastasis-suppressor 0.158218
KLK15 kallikrein-related peptidase 15 0.15817
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.157931
SIX3 SIX homeobox 3 0.157644
SNCG synuclein, gamma (breast cancer-specific protein 1) 0.157163
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.156965
DNM1 dynamin 1 0.156916
TBR1 T-box, brain, 1 0.156521
AACS acetoacetyl-CoA synthetase 0.156174
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.156022
NRGN neurogranin (protein kinase C substrate, RC3) 0.155971
KISS1R KISS1 receptor 0.155461
FDX1 ferredoxin 1 0.155309
CRHR2 corticotropin releasing hormone receptor 2 0.155258
CYCS cytochrome c, somatic 0.154946
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.154631
CGA glycoprotein hormones, alpha polypeptide 0.154526
PTH2 parathyroid hormone 2 0.154
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.153621
PRLR prolactin receptor 0.15335
PSAP prosaposin 0.151
REST RE1-silencing transcription factor 0.150598
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.150303
RXFP3 relaxin/insulin-like family peptide receptor 3 0.149712
EDN2 endothelin 2 0.149653
SSTR1 somatostatin receptor 1 0.149476
SCG5 secretogranin V 0.149476
NMU neuromedin U 0.149115
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.148811
PHGDH phosphoglycerate dehydrogenase 0.14875
SIX1 SIX homeobox 1 0.14875
ADNP activity-dependent neuroprotector homeobox 0.14875
ABAT 4-aminobutyrate aminotransferase 0.148689
B4GALNT2 beta-1,4-N-acetyl-galactosaminyl transferase 2 0.147957
LMNB1 lamin B1 0.147957
GAN gigaxonin 0.147644
GRM1 glutamate receptor, metabotropic 1 0.146831
NCOA1 nuclear receptor coactivator 1 0.146125
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.144625
CRAT carnitine O-acetyltransferase 0.144559
REG1A regenerating islet-derived 1 alpha 0.144229
FXYD1 FXYD domain containing ion transport regulator 1 0.143895
CNTFR ciliary neurotrophic factor receptor 0.143895