basal cell carcinoma Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A skin carcinoma affecting basal cells. (Human Disease Ontology, DOID_2513)
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Genes

319 genes co-occuring with the disease basal cell carcinoma in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
PTCH1 patched 1 2.53746
SMO smoothened, frizzled class receptor 2.23619
GLI1 GLI family zinc finger 1 2.03606
SHH sonic hedgehog 1.88713
GLI2 GLI family zinc finger 2 1.80382
PTGER4 prostaglandin E receptor 4 (subtype EP4) 1.61486
TP53 tumor protein p53 1.59653
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 1.45133
PTCH2 patched 2 1.41052
KRT20 keratin 20, type I 1.36945
CLEC2A C-type lectin domain family 2, member A 1.35594
TLR7 toll-like receptor 7 1.33763
PHLDA1 pleckstrin homology-like domain, family A, member 1 1.32498
SUFU suppressor of fused homolog (Drosophila) 1.32192
KRT15 keratin 15, type I 1.30882
KRT17 keratin 17, type I 1.20526
DAND5 DAN domain family member 5, BMP antagonist 1.15538
KRT14 keratin 14, type I 1.14772
ZNF189 zinc finger protein 189 1.01807
PADI6 peptidyl arginine deiminase, type VI 1.00457
ODF3 outer dense fiber of sperm tails 3 0.99908
MLANA melan-A 0.994439
KRT5 keratin 5, type II 0.993596
KRT8 keratin 8, type II 0.992752
IHH indian hedgehog 0.981373
KRT7 keratin 7, type II 0.976744
ERCC2 excision repair cross-complementation group 2 0.966663
ODF4 outer dense fiber of sperm tails 4 0.938289
GSTM3 glutathione S-transferase mu 3 (brain) 0.930414
KIF4B kinesin family member 4B 0.927105
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like 0.927105
GLI3 GLI family zinc finger 3 0.921323
FOXO4 forkhead box O4 0.901567
GSTTP1 glutathione S-transferase theta pseudogene 1 0.88393
GSTT1 glutathione S-transferase theta 1 0.88393
PCNA proliferating cell nuclear antigen 0.848716
FOXE1 forkhead box E1 0.846259
GSTM1 glutathione S-transferase mu 1 0.834788
RGS22 regulator of G-protein signaling 22 0.828639
FOXL1 forkhead box L1 0.827819
WNT2B wingless-type MMTV integration site family, member 2B 0.825358
CYLD cylindromatosis (turban tumor syndrome) 0.817155
UBAC2 UBA domain containing 2 0.802385
FOXF1 forkhead box F1 0.800744
CD34 CD34 molecule 0.794591
GSTA4 glutathione S-transferase alpha 4 0.793361
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.791721
IVL involucrin 0.788852
DHH desert hedgehog 0.781888
MMP11 matrix metallopeptidase 11 0.774932
GSTA3 glutathione S-transferase alpha 3 0.767985
GSTA2 glutathione S-transferase alpha 2 0.766351
CLPTM1L CLPTM1-like 0.759008
FOXD4L1 forkhead box D4-like 1 0.759008
FOXD4L3 forkhead box D4-like 3 0.759008
GSTA1 glutathione S-transferase alpha 1 0.759008
RHOU ras homolog family member U 0.752492
ZNF396 zinc finger protein 396 0.749644
CDKN2A cyclin-dependent kinase inhibitor 2A 0.729357
SLC45A2 solute carrier family 45, member 2 0.719654
IFI27 interferon, alpha-inducible protein 27 0.713601
KRT35 keratin 35, type I 0.706754
OR10X1 olfactory receptor, family 10, subfamily X, member 1 (gene/pseudogene) 0.702732
KLF10 Kruppel-like factor 10 0.699517
S100A7 S100 calcium binding protein A7 0.698715
MECOM MDS1 and EVI1 complex locus 0.668345
DIS3L DIS3 like exosome 3'-5' exoribonuclease 0.665563
UBE2J1 ubiquitin-conjugating enzyme E2, J1 0.658818
FOXJ3 forkhead box J3 0.648928
EGFR epidermal growth factor receptor 0.642615
FASLG Fas ligand (TNF superfamily, member 6) 0.641433
NOTCH1 notch 1 0.641039
FOXD4 forkhead box D4 0.630813
CD68 CD68 molecule 0.626888
FOXM1 forkhead box M1 0.617094
BCL2 B-cell CLL/lymphoma 2 0.616703
FOXC2 forkhead box C2 0.615921
IFNA1 interferon, alpha 1 0.613183
PIP prolactin-induced protein 0.604981
MMP9 matrix metallopeptidase 9 0.603811
CCND1 cyclin D1 0.586276
FOXB1 forkhead box B1 0.581996
TERT telomerase reverse transcriptase 0.579661
CALML3 calmodulin-like 3 0.577327
BNC1 basonuclin 1 0.570718
FOXN2 forkhead box N2 0.560227
TNC tenascin C 0.560227
TLR8 toll-like receptor 8 0.558285
GLTSCR1 glioma tumor suppressor candidate region gene 1 0.555568
SPATA19 spermatogenesis associated 19 0.550522
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2 0.549359
FOXN4 forkhead box N4 0.546256
S100A2 S100 calcium binding protein A2 0.545868
SOX9 SRY (sex determining region Y)-box 9 0.54393
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.543542
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.542379
IFNA2 interferon, alpha 2 0.540829
RCC2 regulator of chromosome condensation 2 0.532701
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.531928
CD44 CD44 molecule (Indian blood group) 0.529222
TEX101 testis expressed 101 0.528063
KRT10 keratin 10, type I 0.522659
CD53 CD53 molecule 0.520346
SYP synaptophysin 0.520346
FNDC1 fibronectin type III domain containing 1 0.513417
SAP18 Sin3A-associated protein, 18kDa 0.512648
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.510344
ARHGAP9 Rho GTPase activating protein 9 0.508041
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13 0.501527
HHIP hedgehog interacting protein 0.497703
ENO2 enolase 2 (gamma, neuronal) 0.493122
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.491978
SPPL2B signal peptide peptidase like 2B 0.491597
PDGFRL platelet-derived growth factor receptor-like 0.491215
FOXK2 forkhead box K2 0.488549
WNT5A wingless-type MMTV integration site family, member 5A 0.483985
ST7L suppression of tumorigenicity 7 like 0.471089
KRT34 keratin 34, type I 0.470711
PLIN2 perilipin 2 0.469954
RBP2 retinol binding protein 2, cellular 0.462772
OCA2 oculocutaneous albinism II 0.451454
MKI67 marker of proliferation Ki-67 0.451454
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.451078
FOXR1 forkhead box R1 0.448817
RPTN repetin 0.448441
MMP1 matrix metallopeptidase 1 0.437906
HPD 4-hydroxyphenylpyruvate dioxygenase 0.437154
JAG2 jagged 2 0.433772
MIXL1 Mix paired-like homeobox 0.433397
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.42589
FOXP4 forkhead box P4 0.42589
ERCC1 excision repair cross-complementation group 1 0.422515
HRAS Harvey rat sarcoma viral oncogene homolog 0.41727
DSG2 desmoglein 2 0.416896
BAX BCL2-associated X protein 0.416147
FOXN1 forkhead box N1 0.413153
TYR tyrosinase 0.40904
KRT1 keratin 1, type II 0.408292
FOXD2 forkhead box D2 0.405305
RNF139 ring finger protein 139 0.40008
PASD1 PAS domain containing 1 0.399707
FOXA2 forkhead box A2 0.399334
CXCR3 chemokine (C-X-C motif) receptor 3 0.398589
ODF1 outer dense fiber of sperm tails 1 0.398216
CD4 CD4 molecule 0.396353
SAP30 Sin3A-associated protein, 30kDa 0.394863
KRT38 keratin 38, type I 0.393001
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.391885
BNC2 basonuclin 2 0.388909
AR androgen receptor 0.388166
CHGA chromogranin A 0.387423
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.385193
LALBA lactalbumin, alpha- 0.384079
LOR loricrin 0.382966
CARS cysteinyl-tRNA synthetase 0.377773
TYRP1 tyrosinase-related protein 1 0.369628
C2ORF27A chromosome 2 open reading frame 27A 0.368888
XPA xeroderma pigmentosum, complementation group A 0.36741
GSTP1 glutathione S-transferase pi 1 0.36704
KIF4A kinesin family member 4A 0.365193
GREM1 gremlin 1, DAN family BMP antagonist 0.360764
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.360764
ATF2 activating transcription factor 2 0.355972
DST dystonin 0.354499
PRKD1 protein kinase D1 0.348981
KIF27 kinesin family member 27 0.348981
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.346777
HOXC4 homeobox C4 0.344941
KRT31 keratin 31, type I 0.341272
ATRN attractin 0.338707
ICAM1 intercellular adhesion molecule 1 0.337608
KRT4 keratin 4, type II 0.336876
EZR ezrin 0.334315
XPC xeroderma pigmentosum, complementation group C 0.334315
FGF2 fibroblast growth factor 2 (basic) 0.333583
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.32701
KIF7 kinesin family member 7 0.325187
NCAM1 neural cell adhesion molecule 1 0.324823
FAM120A family with sequence similarity 120A 0.323365
FN1 fibronectin 1 0.322273
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 0.321181
CCND2 cyclin D2 0.319726
HLF hepatic leukemia factor 0.317545
CD37 CD37 molecule 0.315003
PAX7 paired box 7 0.314278
B2M beta-2-microglobulin 0.313915
KIF20A kinesin family member 20A 0.313915
JUN jun proto-oncogene 0.313552
TGFB1 transforming growth factor, beta 1 0.312464
FOXO6 forkhead box O6 0.311014
CRABP2 cellular retinoic acid binding protein 2 0.31029
EXOC2 exocyst complex component 2 0.30848
POLM polymerase (DNA directed), mu 0.305226
RBP1 retinol binding protein 1, cellular 0.305226
LGALS3 lectin, galactoside-binding, soluble, 3 0.303059
TP63 tumor protein p63 0.301615
TNF tumor necrosis factor 0.297291
TWIST1 twist family bHLH transcription factor 1 0.292257
FOXN3 forkhead box N3 0.289744
NES nestin 0.289744
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.288668
FOXI1 forkhead box I1 0.285086
MYEOV myeloma overexpressed 0.282225
IGFBP6 insulin-like growth factor binding protein 6 0.279011
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.278297
MSH2 mutS homolog 2 0.277584
B3GAT1 beta-1,3-glucuronyltransferase 1 0.27687
FOXF2 forkhead box F2 0.271886
FOXA3 forkhead box A3 0.27153
COL17A1 collagen, type XVII, alpha 1 0.270819
MMP3 matrix metallopeptidase 3 0.269753
MIR181C microRNA 181c 0.268687
CDC45 cell division cycle 45 0.265494
MAGED1 melanoma antigen family D1 0.263014
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.260891
MMP13 matrix metallopeptidase 13 0.260538
GADD45A growth arrest and DNA-damage-inducible, alpha 0.259124
MMP2 matrix metallopeptidase 2 0.255241
ERBB2 erb-b2 receptor tyrosine kinase 2 0.254183
BIRC5 baculoviral IAP repeat containing 5 0.253831
NEXN nexilin (F actin binding protein) 0.250663
OAF OAF homolog (Drosophila) 0.24996
KRT2 keratin 2, type II 0.249257
MUC6 mucin 6, oligomeric mucus/gel-forming 0.245046
FOXJ2 forkhead box J2 0.240148
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.239799
TRIM29 tripartite motif containing 29 0.238752
HSPH1 heat shock 105kDa/110kDa protein 1 0.235268
TCHH trichohyalin 0.234225
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.233183
TGFBR1 transforming growth factor, beta receptor 1 0.231448
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.227297
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.224884
HES1 hes family bHLH transcription factor 1 0.224196
LAMB2 laminin, beta 2 (laminin S) 0.222479
KRT16 keratin 16, type I 0.222479
CCDC34 coiled-coil domain containing 34 0.222136
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 0.221108
SMAD3 SMAD family member 3 0.220766
ABHD5 abhydrolase domain containing 5 0.217352
ODC1 ornithine decarboxylase 1 0.217012
TGM3 transglutaminase 3 0.214636
ERP29 endoplasmic reticulum protein 29 0.213959
KLF4 Kruppel-like factor 4 (gut) 0.213959
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.212945
AQP3 aquaporin 3 (Gill blood group) 0.211597
HLA-A major histocompatibility complex, class I, A 0.211261
S100A6 S100 calcium binding protein A6 0.210925
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.206913
IRF1 interferon regulatory factor 1 0.205916
FOXQ1 forkhead box Q1 0.205585
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.20229
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.200982
JAG1 jagged 1 0.200656
MAML1 mastermind-like 1 (Drosophila) 0.200006
FOXH1 forkhead box H1 0.200006
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.199681
FOXP2 forkhead box P2 0.198709
RER1 retention in endoplasmic reticulum sorting receptor 1 0.195501
HLA-B major histocompatibility complex, class I, B 0.191408
JUP junction plakoglobin 0.190786
RAB23 RAB23, member RAS oncogene family 0.189551
CST6 cystatin E/M 0.188938
FLG filaggrin 0.188022
KLK3 kallikrein-related peptidase 3 0.187719
FOXE3 forkhead box E3 0.183835
POMC proopiomelanocortin 0.182957
CD63 CD63 molecule 0.18151
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.180937
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.179802
GPC3 glypican 3 0.179239
PTHLH parathyroid hormone-like hormone 0.178682
FZD2 frizzled class receptor 2 0.178403
ZHX2 zinc fingers and homeoboxes 2 0.177301
HLA-C major histocompatibility complex, class I, C 0.177301
KITLG KIT ligand 0.176485
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.174881
MMP7 matrix metallopeptidase 7 0.174093
ITGA6 integrin, alpha 6 0.172291
HAL histidine ammonia-lyase 0.172291
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.171036
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.171036
OGFR opioid growth factor receptor 0.170789
ANGPTL2 angiopoietin-like 2 0.169812
DNTT DNA nucleotidylexotransferase 0.169571
RAD18 RAD18 E3 ubiquitin protein ligase 0.167915
SMAD2 SMAD family member 2 0.166995
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like 0.165874
MIR183 microRNA 183 0.165001
MUC1 mucin 1, cell surface associated 0.164149
ASMT acetylserotonin O-methyltransferase 0.163729
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.163317
HBA1 hemoglobin, alpha 1 0.162306
BCL2L1 BCL2-like 1 0.161912
MGST1 microsomal glutathione S-transferase 1 0.161912
ZFHX3 zinc finger homeobox 3 0.160203
AMBN ameloblastin (enamel matrix protein) 0.15948
GPANK1 G patch domain and ankyrin repeats 1 0.12474
TIMP2 TIMP metallopeptidase inhibitor 2 0.123846
HTN3 histatin 3 0.121547
GNLY granulysin 0.121125
MITF microphthalmia-associated transcription factor 0.120867
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.119328
ENG endoglin 0.114856
NGFR nerve growth factor receptor 0.113144
TIMP1 TIMP metallopeptidase inhibitor 1 0.11112
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.106091
PGR progesterone receptor 0.097951
HAS3 hyaluronan synthase 3 0.097208
MUC2 mucin 2, oligomeric mucus/gel-forming 0.096628
PTPRC protein tyrosine phosphatase, receptor type, C 0.095484
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.09234
CARD17 caspase recruitment domain family, member 17 0.092309
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.090969
TLR9 toll-like receptor 9 0.088449
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.085462
ESR1 estrogen receptor 1 0.083616
MB myoglobin 0.081846
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.074828