bambuterol-3199 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bambuterol-3199 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACOXL acyl-CoA oxidase-like
ADAM7 ADAM metallopeptidase domain 7
ALDOB aldolase B, fructose-bisphosphate
AMACR alpha-methylacyl-CoA racemase
ANTXR1 anthrax toxin receptor 1
APOC4 apolipoprotein C-IV
ARG1 arginase 1
ARL4D ADP-ribosylation factor-like 4D
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CD177 CD177 molecule
CD6 CD6 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK19 cyclin-dependent kinase 19
CDRT1 CMT1A duplicated region transcript 1
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEMIP cell migration inducing protein, hyaluronan binding
CFAP46 cilia and flagella associated protein 46
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLSTN2 calsyntenin 2
COL3A1 collagen, type III, alpha 1
COMMD4 COMM domain containing 4
CORO7 coronin 7
DCTN1 dynactin 1
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DLK2 delta-like 2 homolog (Drosophila)
EGR4 early growth response 4
EMC3 ER membrane protein complex subunit 3
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FOSL2 FOS-like antigen 2
FUT2 fucosyltransferase 2 (secretor status included)
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR68 G protein-coupled receptor 68
GPR85 G protein-coupled receptor 85
GSK3A glycogen synthase kinase 3 alpha
HAP1 huntingtin-associated protein 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IL36RN interleukin 36 receptor antagonist
IRF4 interferon regulatory factor 4
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KIDINS220 kinase D-interacting substrate, 220kDa
KIF17 kinesin family member 17
LAMB4 laminin, beta 4
LAMC3 laminin, gamma 3
LEFTY2 left-right determination factor 2
LIM2 lens intrinsic membrane protein 2, 19kDa
LPCAT4 lysophosphatidylcholine acyltransferase 4
LUZP4 leucine zipper protein 4
LZTS1 leucine zipper, putative tumor suppressor 1
MAP1A microtubule-associated protein 1A
MCF2 MCF.2 cell line derived transforming sequence
MERTK MER proto-oncogene, tyrosine kinase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MT3 metallothionein 3
NUP50 nucleoporin 50kDa
OTOR otoraplin
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLA2G5 phospholipase A2, group V
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRAME preferentially expressed antigen in melanoma
PRPH peripherin
PSD4 pleckstrin and Sec7 domain containing 4
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGIS prostaglandin I2 (prostacyclin) synthase
PTK2B protein tyrosine kinase 2 beta
RPL35A ribosomal protein L35a
RPS4Y1 ribosomal protein S4, Y-linked 1
SAMD4A sterile alpha motif domain containing 4A
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SHOX2 short stature homeobox 2
SIK3 SIK family kinase 3
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SOX15 SRY (sex determining region Y)-box 15
SV2B synaptic vesicle glycoprotein 2B
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
THRB thyroid hormone receptor, beta
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM59L transmembrane protein 59-like
TMLHE trimethyllysine hydroxylase, epsilon
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP63 tumor protein p63
TTLL5 tubulin tyrosine ligase-like family member 5
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF250 zinc finger protein 250
ZNF287 zinc finger protein 287

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACTG2 actin, gamma 2, smooth muscle, enteric
ADGRE5 adhesion G protein-coupled receptor E5
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ALS2CL ALS2 C-terminal like
ANXA1 annexin A1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BAG4 BCL2-associated athanogene 4
BCAS1 breast carcinoma amplified sequence 1
CAPN15 calpain 15
CCDC132 coiled-coil domain containing 132
CD82 CD82 molecule
CEP97 centrosomal protein 97kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CHRM3 cholinergic receptor, muscarinic 3
CLCF1 cardiotrophin-like cytokine factor 1
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CLIC2 chloride intracellular channel 2
CSF1R colony stimulating factor 1 receptor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCR2 chemokine (C-X-C motif) receptor 2
DAGLA diacylglycerol lipase, alpha
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DYSF dysferlin
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENO3 enolase 3 (beta, muscle)
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA2 EPH receptor A2
FADS2 fatty acid desaturase 2
FAM169A family with sequence similarity 169, member A
FAM189A2 family with sequence similarity 189, member A2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FPGS folylpolyglutamate synthase
GAA glucosidase, alpha; acid
GPX1 glutathione peroxidase 1
HIRA histone cell cycle regulator
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IDI2-AS1 IDI2 antisense RNA 1
IL17RA interleukin 17 receptor A
INTS9 integrator complex subunit 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KAT2A K(lysine) acetyltransferase 2A
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
KIAA0754 KIAA0754
KIAA1456 KIAA1456
KIF13A kinesin family member 13A
KRT13 keratin 13, type I
LATS1 large tumor suppressor kinase 1
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LDHB lactate dehydrogenase B
LMBR1L limb development membrane protein 1-like
LPAR4 lysophosphatidic acid receptor 4
LYZ lysozyme
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MCOLN1 mucolipin 1
MPO myeloperoxidase
NAT6 N-acetyltransferase 6 (GCN5-related)
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NXPH4 neurexophilin 4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PARP16 poly (ADP-ribose) polymerase family, member 16
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLA2G15 phospholipase A2, group XV
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PQLC1 PQ loop repeat containing 1
PRR4 proline rich 4 (lacrimal)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RPL13P5 ribosomal protein L13 pseudogene 5
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC22A14 solute carrier family 22, member 14
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPRY2 sprouty homolog 2 (Drosophila)
SRGN serglycin
SYCP2 synaptonemal complex protein 2
TIGD6 tigger transposable element derived 6
TMEM120B transmembrane protein 120B
UPK3B uroplakin 3B
USP27X ubiquitin specific peptidase 27, X-linked
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WDR62 WD repeat domain 62
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF34 zinc finger protein 34
ZNF365 zinc finger protein 365
ZNF573 zinc finger protein 573
ZNF586 zinc finger protein 586