bacterial pneumonia Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A pneumonia involving inflammation of the lungs caused by bacteria. (Human Disease Ontology, DOID_874)
Similar Terms
Downloads & Tools

Genes

197 genes co-occuring with the disease bacterial pneumonia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 1.45441
CRP C-reactive protein, pentraxin-related 1.34766
PDZD11 PDZ domain containing 11 1.31319
HTRA3 HtrA serine peptidase 3 1.27563
SFTPD surfactant protein D 1.15453
TNF tumor necrosis factor 1.0816
TEF thyrotrophic embryonic factor 1.00583
TOB1 transducer of ERBB2, 1 1.00288
PTAFR platelet-activating factor receptor 0.973801
ALB albumin 0.967921
TLR4 toll-like receptor 4 0.953273
MYD88 myeloid differentiation primary response 88 0.947435
TAC1 tachykinin, precursor 1 0.897461
LBP lipopolysaccharide binding protein 0.894179
KAT8 K(lysine) acetyltransferase 8 0.870006
TLR2 toll-like receptor 2 0.843392
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.825768
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.825358
TREM1 triggering receptor expressed on myeloid cells 1 0.820847
IL1B interleukin 1, beta 0.808539
IL10 interleukin 10 0.807718
CCL3 chemokine (C-C motif) ligand 3 0.801974
GLRA1 glycine receptor, alpha 1 0.798692
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.790081
HSF4 heat shock transcription factor 4 0.785984
BOLL boule-like RNA-binding protein 0.777795
IL6 interleukin 6 0.74883
CLEC4D C-type lectin domain family 4, member D 0.745578
CXCL8 chemokine (C-X-C motif) ligand 8 0.697109
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.690694
VASN vasorin 0.684692
POLR3G polymerase (RNA) III (DNA directed) polypeptide G (32kD) 0.660008
ELANE elastase, neutrophil expressed 0.645375
BCHE butyrylcholinesterase 0.643797
CD79A CD79a molecule, immunoglobulin-associated alpha 0.606543
CXCL2 chemokine (C-X-C motif) ligand 2 0.603811
CARTPT CART prepropeptide 0.597961
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.594064
PI3 peptidase inhibitor 3, skin-derived 0.593674
ZFP36L1 ZFP36 ring finger protein-like 1 0.549747
MPO myeloperoxidase 0.545868
LTF lactotransferrin 0.540055
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.537344
LCN2 lipocalin 2 0.535796
CCT2 chaperonin containing TCP1, subunit 2 (beta) 0.529222
LCK LCK proto-oncogene, Src family tyrosine kinase 0.517649
CLEC4E C-type lectin domain family 4, member E 0.503441
PIGR polymeric immunoglobulin receptor 0.48893
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.488169
LY96 lymphocyte antigen 96 0.470332
TLR5 toll-like receptor 5 0.469576
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.466928
JCHAIN joining chain of multimeric IgA and IgM 0.460506
CXCL5 chemokine (C-X-C motif) ligand 5 0.457109
IL17A interleukin 17A 0.454847
CXCR2 chemokine (C-X-C motif) receptor 2 0.441666
UNC119 unc-119 homolog (C. elegans) 0.434148
CSF3 colony stimulating factor 3 (granulocyte) 0.430768
CXCR1 chemokine (C-X-C motif) receptor 1 0.42814
ACE angiotensin I converting enzyme 0.42664
DEFB4A defensin, beta 4A 0.425514
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.425139
C11ORF40 chromosome 11 open reading frame 40 0.42214
ERCC8 excision repair cross-complementation group 8 0.41465
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.408666
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.408292
MAP2K3 mitogen-activated protein kinase kinase 3 0.404557
KLHL21 kelch-like family member 21 0.396353
ADA adenosine deaminase 0.389281
KRT10 keratin 10, type I 0.385193
CD200 CD200 molecule 0.378143
TLR9 toll-like receptor 9 0.370737
ART3 ADP-ribosyltransferase 3 0.36187
MMP8 matrix metallopeptidase 8 0.361133
ART1 ADP-ribosyltransferase 1 0.357814
PITX1 paired-like homeodomain 1 0.354131
DEFB103B defensin, beta 103B 0.352291
GPR135 G protein-coupled receptor 135 0.349349
MAP2K2 mitogen-activated protein kinase kinase 2 0.346409
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.343106
GAA glucosidase, alpha; acid 0.342372
TF transferrin 0.340906
KSR1 kinase suppressor of ras 1 0.33944
ACE2 angiotensin I converting enzyme 2 0.339073
ICAM1 intercellular adhesion molecule 1 0.323365
CLEC3A C-type lectin domain family 3, member A 0.323002
PGLYRP1 peptidoglycan recognition protein 1 0.320454
MUC1 mucin 1, cell surface associated 0.32009
CLEC2B C-type lectin domain family 2, member B 0.318272
WDR5 WD repeat domain 5 0.312464
LACTB lactamase, beta 0.309928
HP haptoglobin 0.303059
CCL13 chemokine (C-C motif) ligand 13 0.299812
BPI bactericidal/permeability-increasing protein 0.298371
HPR haptoglobin-related protein 0.297291
CLEC10A C-type lectin domain family 10, member A 0.295851
AJAP1 adherens junctions associated protein 1 0.294413
XPR1 xenotropic and polytropic retrovirus receptor 1 0.289744
TREM2 triggering receptor expressed on myeloid cells 2 0.289386
BPIFA1 BPI fold containing family A, member 1 0.281153
TSPO translocator protein (18kDa) 0.279011
COPS2 COP9 signalosome subunit 2 0.279011
CAMP cathelicidin antimicrobial peptide 0.278654
CTSB cathepsin B 0.272953
DPEP1 dipeptidase 1 (renal) 0.272241
SPA17 sperm autoantigenic protein 17 0.27153
STAT1 signal transducer and activator of transcription 1, 91kDa 0.269753
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.263722
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family) 0.258064
AADACL3 arylacetamide deacetylase-like 3 0.257005
HES4 hes family bHLH transcription factor 4 0.25207
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.248905
IARS isoleucyl-tRNA synthetase 0.246799
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.245747
PROS2P protein S (beta) pseudogene 0.245046
IRAK3 interleukin-1 receptor-associated kinase 3 0.244696
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.232836
IRF3 interferon regulatory factor 3 0.231795
CCL2 chemokine (C-C motif) ligand 2 0.231102
CD200R1 CD200 receptor 1 0.230063
RETNLB resistin like beta 0.22937
RAET1E retinoic acid early transcript 1E 0.22937
CLCN6 chloride channel, voltage-sensitive 6 0.229024
TXNDC9 thioredoxin domain containing 9 0.226262
HMGB1 high mobility group box 1 0.225229
OR4F29 olfactory receptor, family 4, subfamily F, member 29 0.221793
COL4A6 collagen, type IV, alpha 6 0.220424
CD248 CD248 molecule, endosialin 0.220424
LDHAL6B lactate dehydrogenase A-like 6B 0.218715
HGF hepatocyte growth factor (hepapoietin A; scatter factor) 0.218374
FAM155B family with sequence similarity 155, member B 0.213621
RD3 retinal degeneration 3 0.210925
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 0.210253
DUSP1 dual specificity phosphatase 1 0.210253
BPGM 2,3-bisphosphoglycerate mutase 0.200331
CXCL10 chemokine (C-X-C motif) ligand 10 0.200006
PGAM2 phosphoglycerate mutase 2 (muscle) 0.198064
FTL ferritin, light polypeptide 0.198064
FTH1 ferritin, heavy polypeptide 1 0.197742
C5AR1 complement component 5a receptor 1 0.194232
IL2RA interleukin 2 receptor, alpha 0.193915
CCR2 chemokine (C-C motif) receptor 2 0.192031
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.186811
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.18651
PABPN1 poly(A) binding protein, nuclear 1 0.182666
RCAN1 regulator of calcineurin 1 0.182375
PRTN3 proteinase 3 0.178682
RIPK2 receptor-interacting serine-threonine kinase 2 0.177301
LDHAL6A lactate dehydrogenase A-like 6A 0.171535
ECM1 extracellular matrix protein 1 0.171535
TMEM173 transmembrane protein 173 0.170054
HRH2 histamine receptor H2 0.16933
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.16933
NLRP3 NLR family, pyrin domain containing 3 0.167915
SDC1 syndecan 1 0.167224
IGLV3-9 immunoglobulin lambda variable 3-9 (gene/pseudogene) 0.166768
KLK11 kallikrein-related peptidase 11 0.164149
NPTXR neuronal pentraxin receptor 0.163729
PTBP1 polypyrimidine tract binding protein 1 0.163729
SDC4 syndecan 4 0.160761
PGAM1 phosphoglycerate mutase 1 (brain) 0.158605
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.146605
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 0.14632
ASPN asporin 0.146176
NIPBL Nipped-B homolog (Drosophila) 0.145319
ATXN3 ataxin 3 0.145172
MID2 midline 2 0.145128
RAB27A RAB27A, member RAS oncogene family 0.144998
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.144822
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.144811
ACHE acetylcholinesterase (Yt blood group) 0.144671
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 0.144456
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.144435
FKBP4 FK506 binding protein 4, 59kDa 0.144147
WIPF2 WAS/WASL interacting protein family, member 2 0.144142
ZMPSTE24 zinc metallopeptidase STE24 0.14413
GK glycerol kinase 0.143996
NAIP NLR family, apoptosis inhibitory protein 0.143947
KNTC1 kinetochore associated 1 0.143901
ANO1 anoctamin 1, calcium activated chloride channel 0.143826
NPC2 Niemann-Pick disease, type C2 0.143753
IGLV2-8 immunoglobulin lambda variable 2-8 0.143642
PHF1 PHD finger protein 1 0.143531
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.14339
RHCE Rh blood group, CcEe antigens 0.143326
TPI1 triosephosphate isomerase 1 0.143121
MYLK myosin light chain kinase 0.142878
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.142755
ALPPL2 alkaline phosphatase, placental-like 2 0.142557
ALPP alkaline phosphatase, placental 0.142549
ALPL alkaline phosphatase, liver/bone/kidney 0.142533
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.142207
DAXX death-domain associated protein 0.142163
CHIT1 chitinase 1 (chitotriosidase) 0.142064
UROD uroporphyrinogen decarboxylase 0.142046
COL4A5 collagen, type IV, alpha 5 0.141576
NPC1 Niemann-Pick disease, type C1 0.141055