bacitracin-7448 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the bacitracin-7448 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ADRBK1 adrenergic, beta, receptor kinase 1
AQP3 aquaporin 3 (Gill blood group)
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARID4B AT rich interactive domain 4B (RBP1-like)
ARMC4 armadillo repeat containing 4
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
AURKA aurora kinase A
BEX1 brain expressed, X-linked 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC9 coiled-coil domain containing 9
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP295 centrosomal protein 295kDa
CIC capicua transcriptional repressor
CLDN17 claudin 17
CNOT2 CCR4-NOT transcription complex, subunit 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTH cystathionine gamma-lyase
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DGAT1 diacylglycerol O-acyltransferase 1
DST dystonin
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
EHD1 EH-domain containing 1
EPS8L1 EPS8-like 1
EVA1B eva-1 homolog B (C. elegans)
EVPL envoplakin
EXPH5 exophilin 5
FAM134B family with sequence similarity 134, member B
FAM188A family with sequence similarity 188, member A
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FHL1 four and a half LIM domains 1
GEMIN8 gem (nuclear organelle) associated protein 8
GJB3 gap junction protein, beta 3, 31kDa
GLS2 glutaminase 2 (liver, mitochondrial)
GSPT1 G1 to S phase transition 1
GSTCD glutathione S-transferase, C-terminal domain containing
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXB2 homeobox B2
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IRS2 insulin receptor substrate 2
KHSRP KH-type splicing regulatory protein
LEPR leptin receptor
LMAN1 lectin, mannose-binding, 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MYOF myoferlin
NAAA N-acylethanolamine acid amidase
NCAPH2 non-SMC condensin II complex, subunit H2
NCR2 natural cytotoxicity triggering receptor 2
NF2 neurofibromin 2 (merlin)
NOL6 nucleolar protein 6 (RNA-associated)
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OPCML opioid binding protein/cell adhesion molecule-like
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PIDD1 p53-induced death domain protein 1
PLLP plasmolipin
PLXNB1 plexin B1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP4R4 protein phosphatase 4, regulatory subunit 4
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCAN3 RCAN family member 3
REEP1 receptor accessory protein 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS4 regulator of G-protein signaling 4
RNF122 ring finger protein 122
RNFT2 ring finger protein, transmembrane 2
SAA4 serum amyloid A4, constitutive
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPN sialophorin
SPTBN1 spectrin, beta, non-erythrocytic 1
STAT5B signal transducer and activator of transcription 5B
STIM1 stromal interaction molecule 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAOK1 TAO kinase 1
TBX19 T-box 19
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THBD thrombomodulin
THBS3 thrombospondin 3
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
UNC5B unc-5 homolog B (C. elegans)
USP19 ubiquitin specific peptidase 19
VCX2 variable charge, X-linked 2
VEGFB vascular endothelial growth factor B
WDTC1 WD and tetratricopeptide repeats 1
XDH xanthine dehydrogenase
ZBED1 zinc finger, BED-type containing 1
ZC3H7B zinc finger CCCH-type containing 7B
ZNF211 zinc finger protein 211
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATF7IP2 activating transcription factor 7 interacting protein 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BAGE B melanoma antigen
BAK1 BCL2-antagonist/killer 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRD9 bromodomain containing 9
C12ORF43 chromosome 12 open reading frame 43
C19ORF40 chromosome 19 open reading frame 40
C9ORF40 chromosome 9 open reading frame 40
CBX8 chromobox homolog 8
CEP131 centrosomal protein 131kDa
CFD complement factor D (adipsin)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
COPS7B COP9 signalosome subunit 7B
COQ6 coenzyme Q6 monooxygenase
CPTP ceramide-1-phosphate transfer protein
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND4A DENN/MADD domain containing 4A
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOCK1 dedicator of cytokinesis 1
EAF2 ELL associated factor 2
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
EIF5A2 eukaryotic translation initiation factor 5A2
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
FAM86C1 family with sequence similarity 86, member C1
FBXO31 F-box protein 31
FKBP5 FK506 binding protein 5
FOXC1 forkhead box C1
FSD1 fibronectin type III and SPRY domain containing 1
FZD2 frizzled class receptor 2
GPR27 G protein-coupled receptor 27
GPX2 glutathione peroxidase 2
HIST1H1D histone cluster 1, H1d
HIST1H4F histone cluster 1, H4f
HOXA5 homeobox A5
HPSE heparanase
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL15RA interleukin 15 receptor, alpha
IL17RA interleukin 17 receptor A
IRF9 interferon regulatory factor 9
KDM7A lysine (K)-specific demethylase 7A
LMNB1 lamin B1
LRRC20 leucine rich repeat containing 20
MBNL3 muscleblind-like splicing regulator 3
MCOLN3 mucolipin 3
METTL16 methyltransferase like 16
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOGS mannosyl-oligosaccharide glucosidase
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MUM1 melanoma associated antigen (mutated) 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NEO1 neogenin 1
NT5DC3 5'-nucleotidase domain containing 3
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PCSK7 proprotein convertase subtilisin/kexin type 7
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTCD1 pentatricopeptide repeat domain 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RRAS related RAS viral (r-ras) oncogene homolog
RWDD3 RWD domain containing 3
SETD8 SET domain containing (lysine methyltransferase) 8
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SREK1IP1 SREK1-interacting protein 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TCTN1 tectonic family member 1
TCTN2 tectonic family member 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMPRSS4 transmembrane protease, serine 4
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC4 tetratricopeptide repeat domain 4
USB1 U6 snRNA biogenesis 1
VEGFC vascular endothelial growth factor C
XPA xeroderma pigmentosum, complementation group A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZMAT5 zinc finger, matrin-type 5
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF692 zinc finger protein 692
ZSCAN16 zinc finger and SCAN domain containing 16