bacampicillin-4417 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the bacampicillin-4417 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM1 acyl-CoA synthetase medium-chain family member 1
ADGB androglobin
ADGRA2 adhesion G protein-coupled receptor A2
AIM1L absent in melanoma 1-like
ATN1 atrophin 1
BAZ2B bromodomain adjacent to zinc finger domain, 2B
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BDKRB1 bradykinin receptor B1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CALB2 calbindin 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD10 caspase recruitment domain family, member 10
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD70 CD70 molecule
CDC14B cell division cycle 14B
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDRT1 CMT1A duplicated region transcript 1
CLCA1 chloride channel accessory 1
CLSTN3 calsyntenin 3
COL6A2 collagen, type VI, alpha 2
DCX doublecortin
DGCR8 DGCR8 microprocessor complex subunit
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP1 dual specificity phosphatase 1
EFR3B EFR3 homolog B (S. cerevisiae)
ELN elastin
ETV7 ets variant 7
FAM105A family with sequence similarity 105, member A
FAM149B1 family with sequence similarity 149, member B1
FCMR Fc fragment of IgM receptor
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GGT1 gamma-glutamyltransferase 1
GM2A GM2 ganglioside activator
HCG4 HLA complex group 4 (non-protein coding)
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HIST1H2AK histone cluster 1, H2ak
HLA-DRA major histocompatibility complex, class II, DR alpha
HOXA1 homeobox A1
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
INHA inhibin, alpha
KIF26B kinesin family member 26B
KLF13 Kruppel-like factor 13
KRT16 keratin 16, type I
LEFTY2 left-right determination factor 2
LIMK1 LIM domain kinase 1
LIMS2 LIM and senescent cell antigen-like domains 2
LMX1B LIM homeobox transcription factor 1, beta
LOC100127972 uncharacterized LOC100127972
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MBD2 methyl-CpG binding domain protein 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NPAS3 neuronal PAS domain protein 3
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRTN neurturin
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OSGIN2 oxidative stress induced growth inhibitor family member 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX8 paired box 8
PCDHB17P protocadherin beta 17 pseudogene
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PHLDB1 pleckstrin homology-like domain, family B, member 1
PKN2 protein kinase N2
PYHIN1 pyrin and HIN domain family, member 1
RAB6B RAB6B, member RAS oncogene family
RND1 Rho family GTPase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SKAP1 src kinase associated phosphoprotein 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOX10 SRY (sex determining region Y)-box 10
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
STOML1 stomatin (EPB72)-like 1
SVIL supervillin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TGM2 transglutaminase 2
TMEM206 transmembrane protein 206
TMEM212 transmembrane protein 212
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNK2 tyrosine kinase, non-receptor, 2
TP53I11 tumor protein p53 inducible protein 11
TRIM49 tripartite motif containing 49
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZBTB17 zinc finger and BTB domain containing 17
ZNF230 zinc finger protein 230
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM2 ADAM metallopeptidase domain 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
BAX BCL2-associated X protein
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C19ORF73 chromosome 19 open reading frame 73
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CD79B CD79b molecule, immunoglobulin-associated beta
CIC capicua transcriptional repressor
CORO7 coronin 7
CRYGC crystallin, gamma C
CTRL chymotrypsin-like
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4A DENN/MADD domain containing 4A
DLK2 delta-like 2 homolog (Drosophila)
DTX2 deltex 2, E3 ubiquitin ligase
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM131A family with sequence similarity 131, member A
FBXL7 F-box and leucine-rich repeat protein 7
FGL1 fibrinogen-like 1
FOXI1 forkhead box I1
GADD45G growth arrest and DNA-damage-inducible, gamma
GEM GTP binding protein overexpressed in skeletal muscle
GK2 glycerol kinase 2
GK3P glycerol kinase 3 pseudogene
GPR21 G protein-coupled receptor 21
GRB7 growth factor receptor-bound protein 7
GSTTP1 glutathione S-transferase theta pseudogene 1
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HYAL3 hyaluronoglucosaminidase 3
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF9 interferon regulatory factor 9
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KLF2 Kruppel-like factor 2
LHX1 LIM homeobox 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCTP1 multiple C2 domains, transmembrane 1
MEGF6 multiple EGF-like-domains 6
MMP2 matrix metallopeptidase 2
MUC6 mucin 6, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NRSN2 neurensin 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PCDHGA10 protocadherin gamma subfamily A, 10
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCD1 phospholipase C, delta 1
PRR4 proline rich 4 (lacrimal)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFPL3 ret finger protein-like 3
RHOBTB2 Rho-related BTB domain containing 2
RNF126P1 ring finger protein 126 pseudogene 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPH3A rabphilin 3A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCRN3 secernin 3
SEC14L5 SEC14-like 5 (S. cerevisiae)
SKI SKI proto-oncogene
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SPRR2B small proline-rich protein 2B
TBL1Y transducin (beta)-like 1, Y-linked
TBX19 T-box 19
TCEAL2 transcription elongation factor A (SII)-like 2
TLR5 toll-like receptor 5
TM6SF1 transmembrane 6 superfamily member 1
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TPSG1 tryptase gamma 1
TSNAXIP1 translin-associated factor X interacting protein 1
UPK3B uroplakin 3B
VIM vimentin
ZNF37BP zinc finger protein 37B, pseudogene
ZNF41 zinc finger protein 41
ZNF480 zinc finger protein 480
ZNF573 zinc finger protein 573
ZNF580 zinc finger protein 580
ZNF76 zinc finger protein 76
ZNF816 zinc finger protein 816