b cell activation Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. (Gene Ontology, GO_0042113)
External Link http://amigo.geneontology.org/amigo/term/GO:0042113
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Genes

124 genes participating in the b cell activation biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADA adenosine deaminase
ADAM17 ADAM metallopeptidase domain 17
AICDA activation-induced cytidine deaminase
AKAP17A A kinase (PRKA) anchor protein 17A
ATP11C ATPase, class VI, type 11C
BANK1 B-cell scaffold protein with ankyrin repeats 1
BATF basic leucine zipper transcription factor, ATF-like
BAX BCL2-associated X protein
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BLNK B-cell linker
BST2 bone marrow stromal cell antigen 2
BTK Bruton agammaglobulinemia tyrosine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD180 CD180 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD79A CD79a molecule, immunoglobulin-associated alpha
CD86 CD86 molecule
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CMTM7 CKLF-like MARVEL transmembrane domain containing 7
CR2 complement component (3d/Epstein Barr virus) receptor 2
CTPS1 CTP synthase 1
CXCR5 chemokine (C-X-C motif) receptor 5
DCLRE1C DNA cross-link repair 1C
ERCC1 excision repair cross-complementation group 1
EXO1 exonuclease 1
EXOSC3 exosome component 3
EXOSC6 exosome component 6
FLT3 fms-related tyrosine kinase 3
FNIP1 folliculin interacting protein 1
FZD9 frizzled class receptor 9
GAPT GRB2-binding adaptor protein, transmembrane
GIMAP1 GTPase, IMAP family member 1
GPR183 G protein-coupled receptor 183
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HHEX hematopoietically expressed homeobox
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IFNA10 interferon, alpha 10
IFNA14 interferon, alpha 14
IFNA16 interferon, alpha 16
IFNA17 interferon, alpha 17
IFNA21 interferon, alpha 21
IFNA4 interferon, alpha 4
IFNA5 interferon, alpha 5
IFNA6 interferon, alpha 6
IFNA7 interferon, alpha 7
IFNA8 interferon, alpha 8
IFNB1 interferon, beta 1, fibroblast
IFNE interferon, epsilon
IFNK interferon, kappa
IFNW1 interferon, omega 1
IGBP1 immunoglobulin (CD79A) binding protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IKZF3 IKAROS family zinc finger 3 (Aiolos)
IL10 interleukin 10
IL11 interleukin 11
IL4 interleukin 4
IL7R interleukin 7 receptor
ITFG2 integrin alpha FG-GAP repeat containing 2
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK3 Janus kinase 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF6 Kruppel-like factor 6
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LEF1 lymphoid enhancer-binding factor 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LIG4 ligase IV, DNA, ATP-dependent
LRRC8A leucine rich repeat containing 8 family, member A
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MALT1 MALT1 paracaspase
MEF2C myocyte enhancer factor 2C
MLH1 mutL homolog 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MYB v-myb avian myeloblastosis viral oncogene homolog
NBN nibrin
NFAM1 NFAT activating protein with ITAM motif 1
NHEJ1 nonhomologous end-joining factor 1
NKX2-3 NK2 homeobox 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
ONECUT1 one cut homeobox 1
PFDN1 prefoldin subunit 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL2 phospholipase C-like 2
POLM polymerase (DNA directed), mu
POU1F1 POU class 1 homeobox 1
POU2F2 POU class 2 homeobox 2
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PTK2B protein tyrosine kinase 2 beta
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPRC protein tyrosine phosphatase, receptor type, C
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RNF168 ring finger protein 168, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
SKAP2 src kinase associated phosphoprotein 2
SP3 Sp3 transcription factor
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF3 transcription factor 3
TLR4 toll-like receptor 4
TPD52 tumor protein D52
TXLNA taxilin alpha
VCAM1 vascular cell adhesion molecule 1
VPRBP Vpr (HIV-1) binding protein
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB1 zinc finger and BTB domain containing 1