azurophil granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid. (Gene Ontology, GO_0042582)
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Genes

80 proteins co-occuring with the azurophil granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MPO myeloperoxidase 2.50556
CTSG cathepsin G 2.183
LTF lactotransferrin 2.0554
PRTN3 proteinase 3 2.03144
ELANE elastase, neutrophil expressed 1.75147
BPI bactericidal/permeability-increasing protein 1.59372
AZU1 azurocidin 1 1.50622
GUSB glucuronidase, beta 1.48701
LYZ lysozyme 1.32492
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 1.19571
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 1.15825
CLC Charcot-Leyden crystal galectin 1.01635
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.00547
DEFA3 defensin, alpha 3, neutrophil-specific 0.985854
CD63 CD63 molecule 0.970814
KLK8 kallikrein-related peptidase 8 0.949713
C5AR1 complement component 5a receptor 1 0.822206
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.768171
ALPPL2 alkaline phosphatase, placental-like 2 0.718125
ALPL alkaline phosphatase, liver/bone/kidney 0.71768
ALPP alkaline phosphatase, placental 0.717236
PNN pinin, desmosome associated protein 0.71457
ACPP acid phosphatase, prostate 0.662072
IRF2BP1 interferon regulatory factor 2 binding protein 1 0.635868
LMX1B LIM homeobox transcription factor 1, beta 0.603596
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.589295
DEFA4 defensin, alpha 4, corticostatin 0.573828
CLEC3B C-type lectin domain family 3, member B 0.553905
EPX eosinophil peroxidase 0.548122
ANXA11 annexin A11 0.544823
HCK HCK proto-oncogene, Src family tyrosine kinase 0.539472
CTRL chymotrypsin-like 0.53413
CSF3R colony stimulating factor 3 receptor (granulocyte) 0.519389
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.511233
SRGN serglycin 0.444878
STX3 syntaxin 3 0.410649
CD177 CD177 molecule 0.407529
LBP lipopolysaccharide binding protein 0.387751
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.386979
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.369684
RAB27B RAB27B, member RAS oncogene family 0.367006
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.360896
ALOX5AP arachidonate 5-lipoxygenase-activating protein 0.33511
CAMP cathelicidin antimicrobial peptide 0.331719
SLPI secretory leukocyte peptidase inhibitor 0.331342
CSF3 colony stimulating factor 3 (granulocyte) 0.327581
IL11 interleukin 11 0.323075
CD34 CD34 molecule 0.320826
C5ORF38 chromosome 5 open reading frame 38 0.317082
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.314465
STX4 syntaxin 4 0.300311
FGR FGR proto-oncogene, Src family tyrosine kinase 0.275202
CELA1 chymotrypsin-like elastase family, member 1 0.274101
MALL mal, T-cell differentiation protein-like 0.268969
VAMP8 vesicle-associated membrane protein 8 0.264946
STXBP2 syntaxin binding protein 2 0.254017
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.253653
NCF2 neutrophil cytosolic factor 2 0.250751
CXCR1 chemokine (C-X-C motif) receptor 1 0.247854
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.247492
RBP3 retinol binding protein 3, interstitial 0.237042
ANXA1 annexin A1 0.236683
MMP9 matrix metallopeptidase 9 0.234891
SNAP23 synaptosomal-associated protein, 23kDa 0.234891
CFD complement factor D (adipsin) 0.219265
PHB2 prohibitin 2 0.217861
TNF tumor necrosis factor 0.217511
FPR1 formyl peptide receptor 1 0.215412
CTSC cathepsin C 0.208481
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.207794
CD69 CD69 molecule 0.203022
HLA-A major histocompatibility complex, class I, A 0.196669
STX2 syntaxin 2 0.194045
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.182122
IL3 interleukin 3 0.180339
IL5 interleukin 5 0.179167
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.171937
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.167611
AP3B1 adaptor-related protein complex 3, beta 1 subunit 0.166405
CXCL8 chemokine (C-X-C motif) ligand 8 0.159658