autonomic nervous system Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The enteric, parasympathetic, and sympathetic nervous systems taken together. Generally speaking, the autonomic nervous system regulates the internal environment during both peaceful activity and physical or emotional stress. Autonomic activity is controlled and integrated by the central nervous system, especially the hypothalamus and the solitary nucleus, which receive information relayed from VISCERAL AFFERENTS; these and related central and sensory structures are sometimes (but not here) considered to be part of the autonomic nervous system itself. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002507)
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695 proteins co-occuring with the tissue autonomic nervous system in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
NPY neuropeptide Y 2.50957
REN renin 2.49442
TH tyrosine hydroxylase 2.3898
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 2.33517
TAC1 tachykinin, precursor 1 2.28432
NGF nerve growth factor (beta polypeptide) 2.19137
INS insulin 2.18557
NPS neuropeptide S 2.16444
VIP vasoactive intestinal peptide 2.11179
AMY1B amylase, alpha 1B (salivary) 2.09524
AMY1C amylase, alpha 1C (salivary) 2.09524
AMY1A amylase, alpha 1A (salivary) 2.09364
LEP leptin 2.05889
ACE angiotensin I converting enzyme 2.05354
CALCA calcitonin-related polypeptide alpha 2.00492
RET ret proto-oncogene 1.94673
GDNF glial cell derived neurotrophic factor 1.88684
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 1.85843
CHAT choline O-acetyltransferase 1.8087
NPPA natriuretic peptide A 1.80463
ACHE acetylcholinesterase (Yt blood group) 1.75424
CRH corticotropin releasing hormone 1.70097
SOX10 SRY (sex determining region Y)-box 10 1.68803
GAL galanin/GMAP prepropeptide 1.68503
POMC proopiomelanocortin 1.68005
EDNRB endothelin receptor type B 1.63006
GCG glucagon 1.62407
AVP arginine vasopressin 1.60962
SST somatostatin 1.60415
ADRB2 adrenoceptor beta 2, surface 1.57405
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 1.5594
PHOX2A paired-like homeobox 2a 1.50953
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.4888
NRTN neurturin 1.47709
KNG1 kininogen 1 1.47568
EDN3 endothelin 3 1.47241
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 1.45518
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 1.44497
PPY pancreatic polypeptide 1.43755
PNMT phenylethanolamine N-methyltransferase 1.40478
ADRB1 adrenoceptor beta 1 1.40156
ASCL1 achaete-scute family bHLH transcription factor 1 1.34905
PHOX2B paired-like homeobox 2b 1.32822
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic 1.31965
ELAVL3 ELAV like neuron-specific RNA binding protein 3 1.30478
GPC3 glypican 3 1.29759
BCHE butyrylcholinesterase 1.28143
CCK cholecystokinin 1.26576
GRP gastrin-releasing peptide 1.22648
GHRL ghrelin/obestatin prepropeptide 1.22469
NTS neurotensin 1.21713
CALB2 calbindin 2 1.20067
NTF3 neurotrophin 3 1.18334
CALB1 calbindin 1, 28kDa 1.17935
ADRB3 adrenoceptor beta 3 1.17225
HAND2 heart and neural crest derivatives expressed 2 1.14742
ENO2 enolase 2 (gamma, neuronal) 1.14343
PDYN prodynorphin 1.13058
CHGA chromogranin A 1.1297
FOS FBJ murine osteosarcoma viral oncogene homolog 1.12615
SYP synaptophysin 1.11597
ARTN artemin 1.1142
GFRA1 GDNF family receptor alpha 1 1.09385
TRH thyrotropin-releasing hormone 1.09297
ADCY2 adenylate cyclase 2 (brain) 1.08811
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein 1.08457
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.08325
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 1.07265
MC4R melanocortin 4 receptor 1.06382
CCNA2 cyclin A2 1.06118
PYY peptide YY 1.04533
GAST gastrin 1.04225
HCRT hypocretin (orexin) neuropeptide precursor 1.03609
SAA1 serum amyloid A1 1.01025
CARTPT CART prepropeptide 1.00632
ADM adrenomedullin 1.00632
IL1B interleukin 1, beta 1.00109
IL6 interleukin 6 0.998908
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa 0.998037
BDNF brain-derived neurotrophic factor 0.996295
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2 0.975449
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.953409
AKAP9 A kinase (PRKA) anchor protein 9 0.945656
MLN motilin 0.943935
ADRA1D adrenoceptor alpha 1D 0.929764
TACR1 tachykinin receptor 1 0.927621
STMN2 stathmin 2 0.927621
CNTF ciliary neurotrophic factor 0.918206
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.916496
NGFR nerve growth factor receptor 0.914361
ADRA2A adrenoceptor alpha 2A 0.89902
CNR1 cannabinoid receptor 1 (brain) 0.89902
C11ORF57 chromosome 11 open reading frame 57 0.894346
PIH1D2 PIH1 domain containing 2 0.894346
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.893921
PRNP prion protein 0.891798
B3GAT1 beta-1,3-glucuronyltransferase 1 0.890101
PEG10 paternally expressed 10 0.881627
EDN1 endothelin 1 0.879935
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.879089
UCN urocortin 0.869373
CRP C-reactive protein, pentraxin-related 0.865155
ADRA1B adrenoceptor alpha 1B 0.856312
ADRA1A adrenoceptor alpha 1A 0.847484
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.845805
GNAS GNAS complex locus 0.845385
COMT catechol-O-methyltransferase 0.821502
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.821085
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.818576
GAP43 growth associated protein 43 0.817322
PSPN persephin 0.814815
AANAT aralkylamine N-acetyltransferase 0.812309
PGLS 6-phosphogluconolactonase 0.806465
NOS3 nitric oxide synthase 3 (endothelial cell) 0.80563
AKAP7 A kinase (PRKA) anchor protein 7 0.803961
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.801042
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.796874
TRIP12 thyroid hormone receptor interactor 12 0.795624
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.793126
TNF tumor necrosis factor 0.791877
TLX3 T-cell leukemia homeobox 3 0.791877
SCG2 secretogranin II 0.786468
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.77857
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 0.777325
AGTR1 angiotensin II receptor, type 1 0.776494
PNOC prepronociceptin 0.775249
ALB albumin 0.774004
TTR transthyretin 0.76157
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.76157
TRAPPC9 trafficking protein particle complex 9 0.7595
LEPR leptin receptor 0.755364
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.747515
HTN3 histatin 3 0.740503
ALK anaplastic lymphoma receptor tyrosine kinase 0.729385
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3 0.728152
AVL9 AVL9 homolog (S. cerevisiase) 0.726918
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 0.713369
RPS19 ribosomal protein S19 0.710909
GAN gigaxonin 0.696989
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.696581
ADRBK1 adrenergic, beta, receptor kinase 1 0.694537
DNAH8 dynein, axonemal, heavy chain 8 0.692085
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.690042
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.68188
GHSR growth hormone secretagogue receptor 0.681471
LIPE lipase, hormone-sensitive 0.677803
ADRA2C adrenoceptor alpha 2C 0.673728
CA5B carbonic anhydrase VB, mitochondrial 0.671692
ZDHHC23 zinc finger, DHHC-type containing 23 0.670471
SLC25A45 solute carrier family 25, member 45 0.670064
IFT122 intraflagellar transport 122 0.661523
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.65746
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.65746
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.656242
NTF4 neurotrophin 4 0.656242
GFAP glial fibrillary acidic protein 0.656242
MME membrane metallo-endopeptidase 0.650966
NMU neuromedin U 0.649749
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.649344
MLX MLX, MAX dimerization protein 0.649344
RASGEF1A RasGEF domain family, member 1A 0.649344
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.641643
NRG1 neuregulin 1 0.639214
GLTP glycolipid transfer protein 0.635976
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.630314
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.622639
HOXB5 homeobox B5 0.617796
PCDHA7 protocadherin alpha 7 0.616183
MYO5A myosin VA (heavy chain 12, myoxin) 0.616183
VGF VGF nerve growth factor inducible 0.607722
EDNRA endothelin receptor type A 0.601686
UCN3 urocortin 3 0.596058
GRM2 glutamate receptor, metabotropic 2 0.591641
UCN2 urocortin 2 0.589635
GIP gastric inhibitory polypeptide 0.579617
TACR3 tachykinin receptor 3 0.578416
TEF thyrotrophic embryonic factor 0.578016
AGRP agouti related neuropeptide 0.576816
ADM2 adrenomedullin 2 0.576816
HCRTR1 hypocretin (orexin) receptor 1 0.571219
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.560449
PENK proenkephalin 0.558856
MAOB monoamine oxidase B 0.555274
ATG4C autophagy related 4C, cysteine peptidase 0.55408
HMOX2 heme oxygenase 2 0.546533
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.545342
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.544946
KIAA0101 KIAA0101 0.544549
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.543359
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.539
NPPB natriuretic peptide B 0.538209
EPAS1 endothelial PAS domain protein 1 0.537416
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.531089
OPRL1 opiate receptor-like 1 0.527534
MNX1 motor neuron and pancreas homeobox 1 0.527534
SOD2 superoxide dismutase 2, mitochondrial 0.527139
HTN1 histatin 1 0.525166
SDHAF2 succinate dehydrogenase complex assembly factor 2 0.523982
TRPC7 transient receptor potential cation channel, subfamily C, member 7 0.51453
CREB1 cAMP responsive element binding protein 1 0.512564
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit 0.509027
ODC1 ornithine decarboxylase 1 0.508242
RYR2 ryanodine receptor 2 (cardiac) 0.507064
OPRM1 opioid receptor, mu 1 0.505495
CRHR1 corticotropin releasing hormone receptor 1 0.50471
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.498832
HOXA4 homeobox A4 0.492572
MRGPRF MAS-related GPR, member F 0.489057
MYLK myosin light chain kinase 0.488276
REEP2 receptor accessory protein 2 0.483986
CORT cortistatin 0.482038
SCGN secretagogin, EF-hand calcium binding protein 0.48087
TTLL7 tubulin tyrosine ligase-like family member 7 0.480091
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.480091
ACTBL2 actin, beta-like 2 0.478534
NOS1 nitric oxide synthase 1 (neuronal) 0.477756
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.469987
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1 0.469599
TMEM127 transmembrane protein 127 0.466885
ECE1 endothelin converting enzyme 1 0.464174
CLDN11 claudin 11 0.463013
TGFB1 transforming growth factor, beta 1 0.461465
NUMBL numb homolog (Drosophila)-like 0.459145
TPH1 tryptophan hydroxylase 1 0.458373
IGF1 insulin-like growth factor 1 (somatomedin C) 0.4576
RGMB repulsive guidance molecule family member b 0.453355
MGAM maltase-glucoamylase 0.452198
GALP galanin-like peptide 0.451428
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.448346
MAOA monoamine oxidase A 0.447192
NES nestin 0.443731
SPAG7 sperm associated antigen 7 0.440274
CD4 CD4 molecule 0.43989
DIO2 deiodinase, iodothyronine, type II 0.438356
CHGB chromogranin B 0.436822
TACR2 tachykinin receptor 2 0.434906
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F 0.434906
NEUROD1 neuronal differentiation 1 0.43146
GNS glucosamine (N-acetyl)-6-sulfatase 0.430312
BGLAP bone gamma-carboxyglutamate (gla) protein 0.427636
MECP2 methyl CpG binding protein 2 0.424199
JUN jun proto-oncogene 0.420766
NCAM1 neural cell adhesion molecule 1 0.416576
RPP21 ribonuclease P/MRP 21kDa subunit 0.412011
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.406315
RETN resistin 0.404039
PTH parathyroid hormone 0.402523
CBS cystathionine-beta-synthase 0.40025
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.396087
GNG3 guanine nucleotide binding protein (G protein), gamma 3 0.395331
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.391931
MIR184 microRNA 184 0.391553
S100B S100 calcium binding protein B 0.390421
RGS2 regulator of G-protein signaling 2 0.387027
UNC13A unc-13 homolog A (C. elegans) 0.38439
KCNK4 potassium channel, two pore domain subfamily K, member 4 0.384013
NOTCH1 notch 1 0.381003
SRR serine racemase 0.380627
ASIC3 acid sensing (proton gated) ion channel 3 0.379875
PRSS21 protease, serine, 21 (testisin) 0.378748
MAP1S microtubule-associated protein 1S 0.377245
MAP2 microtubule-associated protein 2 0.375743
KIF1BP KIF1 binding protein 0.375368
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.374243
NRP1 neuropilin 1 0.371619
DRGX dorsal root ganglia homeobox 0.370121
TMEM100 transmembrane protein 100 0.367129
MRGPRE MAS-related GPR, member E 0.364513
ADRA2B adrenoceptor alpha 2B 0.363393
UBQLN1 ubiquilin 1 0.362646
HRH2 histamine receptor H2 0.360782
ATF3 activating transcription factor 3 0.360409
CST4 cystatin S 0.360409
SORBS2 sorbin and SH3 domain containing 2 0.358174
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.357802
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.357058
PRB3 proline-rich protein BstNI subfamily 3 0.352227
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.34926
PLAT plasminogen activator, tissue 0.347038
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.337072
VWF von Willebrand factor 0.335968
HRH1 histamine receptor H1 0.334498
RBMS3 RNA binding motif, single stranded interacting protein 3 0.33046
IGLV1-51 immunoglobulin lambda variable 1-51 0.329727
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.329727
SYT1 synaptotagmin I 0.328628
C5ORF38 chromosome 5 open reading frame 38 0.32753
VAV3 vav 3 guanine nucleotide exchange factor 0.32497
ADA adenosine deaminase 0.320591
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.320591
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.319498
FGF2 fibroblast growth factor 2 (basic) 0.317679
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 0.316951
TYRO3 TYRO3 protein tyrosine kinase 0.314046
TUBA1A tubulin, alpha 1a 0.310059
LARS leucyl-tRNA synthetase 0.309697
GAPVD1 GTPase activating protein and VPS9 domains 1 0.308974
BMP4 bone morphogenetic protein 4 0.308612
PHACTR4 phosphatase and actin regulator 4 0.308251
FASN fatty acid synthase 0.307889
GUCY2C guanylate cyclase 2C 0.307167
AVPR2 arginine vasopressin receptor 2 0.306805
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.306083
NPR1 natriuretic peptide receptor 1 0.305361
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.305361
DOK6 docking protein 6 0.303198
SSTR2 somatostatin receptor 2 0.301398
SCN10A sodium channel, voltage gated, type X alpha subunit 0.30032
MURC muscle-related coiled-coil protein 0.298165
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.297447
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.29673
GCSAM germinal center-associated, signaling and motility 0.296013
IGLV1-36 immunoglobulin lambda variable 1-36 0.295655
EDN2 endothelin 2 0.294939
ETV3 ets variant 3 0.293508
CNRIP1 cannabinoid receptor interacting protein 1 0.293151
MC3R melanocortin 3 receptor 0.292793
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.292436
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.290295
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.288158
PRAF2 PRA1 domain family, member 2 0.287447
ZFR zinc finger RNA binding protein 0.287447
MAN2C1 mannosidase, alpha, class 2C, member 1 0.286736
CXCL12 chemokine (C-X-C motif) ligand 12 0.285671
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.284962
AKAP1 A kinase (PRKA) anchor protein 1 0.284253
BARD1 BRCA1 associated RING domain 1 0.283899
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.28213
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.281423
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.281423
THY1 Thy-1 cell surface antigen 0.280717
DPP4 dipeptidyl-peptidase 4 0.280717
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.278603
NPPC natriuretic peptide C 0.2779
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.276846
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.275444
IGLV1-47 immunoglobulin lambda variable 1-47 0.271604
PER2 period circadian clock 2 0.271604
ASMT acetylserotonin O-methyltransferase 0.269867
MOB4 MOB family member 4, phocein 0.268828
PROKR1 prokineticin receptor 1 0.268828
PYGB phosphorylase, glycogen; brain 0.265725
RGS4 regulator of G-protein signaling 4 0.265381
PYGL phosphorylase, glycogen, liver 0.264696
STRN4 striatin, calmodulin binding protein 4 0.263669
NF1 neurofibromin 1 0.263669
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.262645
PLXNA4 plexin A4 0.261284
ACE2 angiotensin I converting enzyme 2 0.260945
PYGM phosphorylase, glycogen, muscle 0.260267
SATB2 SATB homeobox 2 0.260267
GHRH growth hormone releasing hormone 0.258917
TXNL4B thioredoxin-like 4B 0.258917
GRM4 glutamate receptor, metabotropic 4 0.25858
GNB5 guanine nucleotide binding protein (G protein), beta 5 0.257237
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.25457
HSPA4 heat shock 70kDa protein 4 0.252919
BCO1 beta-carotene oxygenase 1 0.252261
SLC22A3 solute carrier family 22 (organic cation transporter), member 3 0.251606
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.251606
SPATS2L spermatogenesis associated, serine-rich 2-like 0.249329
PAX3 paired box 3 0.24804
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.247079
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.24486
CHRM2 cholinergic receptor, muscarinic 2 0.244545
IRS1 insulin receptor substrate 1 0.244232
HOMER2 homer scaffolding protein 2 0.243294
DNTT DNA nucleotidylexotransferase 0.242983
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.242363
TEPP testis, prostate and placenta expressed 0.242363
PRDM16 PR domain containing 16 0.242054
AQP2 aquaporin 2 (collecting duct) 0.241746
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.24052
GLP1R glucagon-like peptide 1 receptor 0.239913
IL10 interleukin 10 0.239307
ALPPL2 alkaline phosphatase, placental-like 2 0.239007
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.239007
MGP matrix Gla protein 0.238706
ALPL alkaline phosphatase, liver/bone/kidney 0.238406
ALPP alkaline phosphatase, placental 0.23781
HTRA1 HtrA serine peptidase 1 0.23781
GGN gametogenetin 0.237513
YME1L1 YME1-like 1 ATPase 0.237513
NPR3 natriuretic peptide receptor 3 0.236921
HAND1 heart and neural crest derivatives expressed 1 0.235457
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.23459
WNT1 wingless-type MMTV integration site family, member 1 0.23459
INSR insulin receptor 0.234016
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.232881
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 0.232317
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.232039
HLX H2.0-like homeobox 0.231482
ANXA7 annexin A7 0.230931
FN1 fibronectin 1 0.230656
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.230382
RIMS1 regulating synaptic membrane exocytosis 1 0.23011
ZEB2 zinc finger E-box binding homeobox 2 0.229839
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.229299
DPYS dihydropyrimidinase 0.229299
NT5E 5'-nucleotidase, ecto (CD73) 0.229032
CD79A CD79a molecule, immunoglobulin-associated alpha 0.229032
MRGPRX1 MAS-related GPR, member X1 0.228497
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.228234
PTK7 protein tyrosine kinase 7 (inactive) 0.227445
GLB1 galactosidase, beta 1 0.226411
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.226155
RHOF ras homolog family member F (in filopodia) 0.224645
LPL lipoprotein lipase 0.22415
MBTPS2 membrane-bound transcription factor peptidase, site 2 0.223419
PSD pleckstrin and Sec7 domain containing 0.223177
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.222699
EIF6 eukaryotic translation initiation factor 6 0.22246
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.22246
CRTC3 CREB regulated transcription coactivator 3 0.22246
NOG noggin 0.222224
BMP2 bone morphogenetic protein 2 0.221061
IL2 interleukin 2 0.219485
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.219264
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.219264
PCGF1 polycomb group ring finger 1 0.21883
SYN1 synapsin I 0.217974
HLA-DOB major histocompatibility complex, class II, DO beta 0.217554
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.215928
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 0.215534
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.215341
ACY3 aminoacylase 3 0.214202
MPO myeloperoxidase 0.214202
GRB2 growth factor receptor-bound protein 2 0.213471
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.213112
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 0.212413
NTNG1 netrin G1 0.212413
GFRA2 GDNF family receptor alpha 2 0.193438
SCAMP2 secretory carrier membrane protein 2 0.193419
GRM1 glutamate receptor, metabotropic 1 0.19326
SYBU syntabulin (syntaxin-interacting) 0.193052
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.192861
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.192806
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.192467
MTX3 metaxin 3 0.19235
KCNK10 potassium channel, two pore domain subfamily K, member 10 0.192345
DRG2 developmentally regulated GTP binding protein 2 0.192339
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.192339
SV2A synaptic vesicle glycoprotein 2A 0.191639
HOMER1 homer scaffolding protein 1 0.191632
SNPH syntaphilin 0.190863
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.188216
APLP2 amyloid beta (A4) precursor-like protein 2 0.187911
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.187668
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.187588
RESP18 regulated endocrine-specific protein 18 0.186783
KIFAP3 kinesin-associated protein 3 0.186441
GDF5 growth differentiation factor 5 0.186315
SV2C synaptic vesicle glycoprotein 2C 0.186284
MTX2 metaxin 2 0.186239
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 0.185652
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.185101
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.184544
RPIA ribose 5-phosphate isomerase A 0.184418
MYO1B myosin IB 0.184329
GUK1 guanylate kinase 1 0.184307
KIF5B kinesin family member 5B 0.184196
MTX1 metaxin 1 0.183406
TEN1 TEN1 CST complex subunit 0.183082
TRIM15 tripartite motif containing 15 0.182516
TRIM10 tripartite motif containing 10 0.182476
RACGAP1 Rac GTPase activating protein 1 0.182409
HBG2 hemoglobin, gamma G 0.181967
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.181909
INSRR insulin receptor-related receptor 0.181773
IL1RAP interleukin 1 receptor accessory protein 0.181741
GRM7 glutamate receptor, metabotropic 7 0.181741
TRIM26 tripartite motif containing 26 0.18091
STRN striatin, calmodulin binding protein 0.180605
GRM5 glutamate receptor, metabotropic 5 0.18039
PAM peptidylglycine alpha-amidating monooxygenase 0.180293
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 0.180147
TTL tubulin tyrosine ligase 0.180147
BSN bassoon presynaptic cytomatrix protein 0.180098
DMD dystrophin 0.179898
SNAPIN SNAP-associated protein 0.179798
SV2B synaptic vesicle glycoprotein 2B 0.178913
GRM6 glutamate receptor, metabotropic 6 0.178913
AGPS alkylglycerone phosphate synthase 0.178779
KCNK18 potassium channel, two pore domain subfamily K, member 18 0.178442
KIF1A kinesin family member 1A 0.177471
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8 0.177434
NCK1 NCK adaptor protein 1 0.177404
SRGN serglycin 0.177374
SERPINA4 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.177352
INTU inturned planar cell polarity protein 0.176263
TPTE transmembrane phosphatase with tensin homology 0.176078
TMEM132D transmembrane protein 132D 0.175204
REEP1 receptor accessory protein 1 0.17447
CCDC130 coiled-coil domain containing 130 0.173386
FFAR3 free fatty acid receptor 3 0.1733
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.170799
VIPR1 vasoactive intestinal peptide receptor 1 0.170508
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.170393
STX8 syntaxin 8 0.168489
PSENEN presenilin enhancer gamma secretase subunit 0.168476
DNM2 dynamin 2 0.167247
SLC7A4 solute carrier family 7, member 4 0.166251
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.166181
SYT7 synaptotagmin VII 0.164122
VIPR2 vasoactive intestinal peptide receptor 2 0.163631
PGRMC2 progesterone receptor membrane component 2 0.163631
SPON1 spondin 1, extracellular matrix protein 0.162778
MN1 meningioma (disrupted in balanced translocation) 1 0.162582
BANF1 barrier to autointegration factor 1 0.158673
PLXNA1 plexin A1 0.15819
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B 0.157883
REXO2 RNA exonuclease 2 0.1575
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.153556
ODF2 outer dense fiber of sperm tails 2 0.15295
SCN3A sodium channel, voltage gated, type III alpha subunit 0.150667
VEZF1 vascular endothelial zinc finger 1 0.14996
CBLN3 cerebellin 3 precursor 0.149535
C1D C1D nuclear receptor corepressor 0.148665
NOTUM notum pectinacetylesterase homolog (Drosophila) 0.14864
SRRM1 serine/arginine repetitive matrix 1 0.142383
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.142383
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic 0.14177
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.141492
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.141186
CADM1 cell adhesion molecule 1 0.140472
ISCU iron-sulfur cluster assembly enzyme 0.139872
TRIM47 tripartite motif containing 47 0.139555
CAV2 caveolin 2 0.138326
MAPK8 mitogen-activated protein kinase 8 0.138029
ART3 ADP-ribosyltransferase 3 0.137669
TRPM8 transient receptor potential cation channel, subfamily M, member 8 0.137549
PTPRG protein tyrosine phosphatase, receptor type, G 0.134963
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 0.134303
EGLN1 egl-9 family hypoxia-inducible factor 1 0.133073
ITCH itchy E3 ubiquitin protein ligase 0.132977
CD6 CD6 molecule 0.132528
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.132399
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.132335
PLCB4 phospholipase C, beta 4 0.132047
BORA bora, aurora kinase A activator 0.132015
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.131694
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.131497
EDA ectodysplasin A 0.131104
GPR148 G protein-coupled receptor 148 0.130612
SYT2 synaptotagmin II 0.129388
PDE9A phosphodiesterase 9A 0.128886
SOX8 SRY (sex determining region Y)-box 8 0.127262
BIRC2 baculoviral IAP repeat containing 2 0.127194
PZP pregnancy-zone protein 0.126547
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 0.126547
PPT1 palmitoyl-protein thioesterase 1 0.126478
PDZD4 PDZ domain containing 4 0.125088
MAX MYC associated factor X 0.123398
NSF N-ethylmaleimide-sensitive factor 0.122508
KIF1B kinesin family member 1B 0.122292
GFRA3 GDNF family receptor alpha 3 0.12186
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.121752
EEF2 eukaryotic translation elongation factor 2 0.121249
STK38 serine/threonine kinase 38 0.119534
TNS1 tensin 1 0.119498
NALCN sodium leak channel, non selective 0.119388
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.119352
TNXA tenascin XA (pseudogene) 0.119352
TNXB tenascin XB 0.119352
HOXA13 homeobox A13 0.118985
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.11891
PRSS3 protease, serine, 3 0.118873
DOK4 docking protein 4 0.118761
P2RY1 purinergic receptor P2Y, G-protein coupled, 1 0.116449
SHARPIN SHANK-associated RH domain interactor 0.116147
BRD4 bromodomain containing 4 0.114709
CHRM1 cholinergic receptor, muscarinic 1 0.114633
KRT86 keratin 86, type II 0.114556
DCPS decapping enzyme, scavenger 0.114518
GPBAR1 G protein-coupled bile acid receptor 1 0.11383
NTNG2 netrin G2 0.113104
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.112755
INA internexin neuronal intermediate filament protein, alpha 0.111749
NEO1 neogenin 1 0.111556
WRN Werner syndrome, RecQ helicase-like 0.111402
RIC8A RIC8 guanine nucleotide exchange factor A 0.111286
LTK leukocyte receptor tyrosine kinase 0.11117
PDE1A phosphodiesterase 1A, calmodulin-dependent 0.111091
IQGAP2 IQ motif containing GTPase activating protein 2 0.110856
KCNK9 potassium channel, two pore domain subfamily K, member 9 0.110425
DLK1 delta-like 1 homolog (Drosophila) 0.109994
L1CAM L1 cell adhesion molecule 0.109916
ABAT 4-aminobutyrate aminotransferase 0.109564
LATS2 large tumor suppressor kinase 2 0.109525
PBX3 pre-B-cell leukemia homeobox 3 0.10929
POFUT1 protein O-fucosyltransferase 1 0.109251
CBLN2 cerebellin 2 precursor 0.109173
MAVS mitochondrial antiviral signaling protein 0.109173
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.108618
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) 0.108262
IVD isovaleryl-CoA dehydrogenase 0.108222
SCN2A sodium channel, voltage gated, type II alpha subunit 0.108064
FLNA filamin A, alpha 0.10755
BTNL2 butyrophilin-like 2 0.107431
MYLK3 myosin light chain kinase 3 0.107312
MAT1A methionine adenosyltransferase I, alpha 0.107194
NTN1 netrin 1 0.107035
HOXB7 homeobox B7 0.106835
CRYGD crystallin, gamma D 0.106835
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.106635
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.106034
TSPO translocator protein (18kDa) 0.105795
NPEPPS aminopeptidase puromycin sensitive 0.105715
MIR210 microRNA 210 0.105395
CHD3 chromodomain helicase DNA binding protein 3 0.105116
LAD1 ladinin 1 0.105116
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.104632
LGALS4 lectin, galactoside-binding, soluble, 4 0.104188
KLK8 kallikrein-related peptidase 8 0.104188
PON2 paraoxonase 2 0.104067
ADCY1 adenylate cyclase 1 (brain) 0.103059
FOXD3 forkhead box D3 0.102816
LHX3 LIM homeobox 3 0.102653
TOM1 target of myb1 (chicken) 0.102653
NELFCD negative elongation factor complex member C/D 0.102613
RNF115 ring finger protein 115 0.102002
OPHN1 oligophrenin 1 0.101961
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20 0.101433
ELSPBP1 epididymal sperm binding protein 1 0.101433
SHH sonic hedgehog 0.100536
MYLIP myosin regulatory light chain interacting protein 0.100454
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.100454
GSTA2 glutathione S-transferase alpha 2 0.100413
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.10029
HIPK2 homeodomain interacting protein kinase 2 0.100167
MARK3 MAP/microtubule affinity-regulating kinase 3 0.100003
GSTA1 glutathione S-transferase alpha 1 0.099962
NTSR1 neurotensin receptor 1 (high affinity) 0.099921
STX1A syntaxin 1A (brain) 0.099552
HOXD9 homeobox D9 0.099225
LMO1 LIM domain only 1 (rhombotin 1) 0.098939
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 0.098939
BDKRB1 bradykinin receptor B1 0.098898
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1 0.098528
EBF3 early B-cell factor 3 0.098363
LIN28B lin-28 homolog B (C. elegans) 0.098363
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.098239
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.098239
PBX2 pre-B-cell leukemia homeobox 2 0.098115
SSR1 signal sequence receptor, alpha 0.098033
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.097785
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.097497
ARMC10 armadillo repeat containing 10 0.097414
ADORA1 adenosine A1 receptor 0.09725
PRIMA1 proline rich membrane anchor 1 0.097208
WDFY2 WD repeat and FYVE domain containing 2 0.097126
NRG3 neuregulin 3 0.097126
MARS methionyl-tRNA synthetase 0.096509
GATA2 GATA binding protein 2 0.096425
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.096301
PTMS parathymosin 0.096176
EVC2 Ellis van Creveld syndrome 2 0.096135
BMP10 bone morphogenetic protein 10 0.095844
AQP1 aquaporin 1 (Colton blood group) 0.095761
PROS1 protein S (alpha) 0.095264
RGMA repulsive guidance molecule family member a 0.094809
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2 0.094809
RIPK4 receptor-interacting serine-threonine kinase 4 0.094767
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.094685
ANO1 anoctamin 1, calcium activated chloride channel 0.09456
CCKAR cholecystokinin A receptor 0.094519
GCK glucokinase (hexokinase 4) 0.094436
CASZ1 castor zinc finger 1 0.09402
DLAT dihydrolipoamide S-acetyltransferase 0.093895
FKBP4 FK506 binding protein 4, 59kDa 0.093687
JMJD6 jumonji domain containing 6 0.093603
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.093562
HOXB8 homeobox B8 0.093562
ISL1 ISL LIM homeobox 1 0.093395
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.093312
LYAR Ly1 antibody reactive 0.093229
BBS2 Bardet-Biedl syndrome 2 0.093187
KCNIP4 Kv channel interacting protein 4 0.092729
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.092646
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.092605
HK3 hexokinase 3 (white cell) 0.092605
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.09248
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.092439
HOXB9 homeobox B9 0.092356
GLP2R glucagon-like peptide 2 receptor 0.092147
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.091353
DOCK7 dedicator of cytokinesis 7 0.091311
COLEC12 collectin sub-family member 12 0.091186
TMEM245 transmembrane protein 245 0.091186
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2 0.090977
WTIP Wilms tumor 1 interacting protein 0.090518
PLIN1 perilipin 1 0.090476
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.090435
RNASEH2A ribonuclease H2, subunit A 0.090351
STX1B syntaxin 1B 0.090018