autonomic nervous system disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

227 genes co-occuring with the disease autonomic nervous system disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
INS insulin 1.84727
PPY pancreatic polypeptide 1.69815
CALCA calcitonin-related polypeptide alpha 1.6256
TAC1 tachykinin, precursor 1 1.58046
TTR transthyretin 1.48867
NPS neuropeptide S 1.47725
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 1.45001
MAP6D1 MAP6 domain containing 1 1.43815
ALB albumin 1.29178
GCG glucagon 1.2813
NGF nerve growth factor (beta polypeptide) 1.2005
NPY neuropeptide Y 1.11603
MLN motilin 1.07992
HBA1 hemoglobin, alpha 1 0.992752
HBA2 hemoglobin, alpha 2 0.968341
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.944521
CBR4 carbonyl reductase 4 0.940364
CCK cholecystokinin 0.882292
REN renin 0.868777
SST somatostatin 0.854449
TACR1 tachykinin receptor 1 0.797052
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.743141
GPC3 glypican 3 0.742329
DPYSL5 dihydropyrimidinase-like 5 0.734217
ACE angiotensin I converting enzyme 0.732596
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.724502
ZDHHC23 zinc finger, DHHC-type containing 23 0.72329
ANKLE2 ankyrin repeat and LEM domain containing 2 0.705949
CDK13 cyclin-dependent kinase 13 0.698715
FRMPD1 FERM and PDZ domain containing 1 0.690694
CLDN11 claudin 11 0.667947
GIP gastric inhibitory polypeptide 0.66596
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.661594
GAST gastrin 0.659215
DPYSL4 dihydropyrimidinase-like 4 0.652484
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.650113
LIN9 lin-9 DREAM MuvB core complex component 0.642615
NPPA natriuretic peptide A 0.625711
CD6 CD6 molecule 0.615529
TH tyrosine hydroxylase 0.60069
MLNR motilin receptor 0.571107
ACHE acetylcholinesterase (Yt blood group) 0.544705
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 0.536957
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.529994
SORD sorbitol dehydrogenase 0.512648
ADRA1A adrenoceptor alpha 1A 0.508808
REXO2 RNA exonuclease 2 0.476393
AVP arginine vasopressin 0.474877
BMP2K BMP2 inducible kinase 0.465794
KNG1 kininogen 1 0.453716
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.437154
SPTLC1 serine palmitoyltransferase, long chain base subunit 1 0.42289
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.42139
C1QC complement component 1, q subcomponent, C chain 0.41727
SKAP2 src kinase associated phosphoprotein 2 0.415773
APCS amyloid P component, serum 0.412031
MME membrane metallo-endopeptidase 0.411283
CHAT choline O-acetyltransferase 0.410535
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.405305
FAM134B family with sequence similarity 134, member B 0.398962
BGLAP bone gamma-carboxyglutamate (gla) protein 0.390769
POMC proopiomelanocortin 0.386308
ADAM2 ADAM metallopeptidase domain 2 0.369258
SYNM synemin, intermediate filament protein 0.36704
SYCP3 synaptonemal complex protein 3 0.355604
PRSS50 protease, serine, 50 0.353395
PYY peptide YY 0.346409
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.337608
TNF tumor necrosis factor 0.33651
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.335778
MBD5 methyl-CpG binding domain protein 5 0.334315
EDN1 endothelin 1 0.328834
WNK1 WNK lysine deficient protein kinase 1 0.328105
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.328105
IGF1 insulin-like growth factor 1 (somatomedin C) 0.325552
AGK acylglycerol kinase 0.323002
FBXO17 F-box protein 17 0.321909
MMP10 matrix metallopeptidase 10 0.302337
GSN gelsolin 0.301976
BRS3 bombesin-like receptor 3 0.299812
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.299452
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.299092
FA2H fatty acid 2-hydroxylase 0.287235
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 0.285802
TTC34 tetratricopeptide repeat domain 34 0.283297
ETV3 ets variant 3 0.28151
IL1B interleukin 1, beta 0.28151
VIP vasoactive intestinal peptide 0.27794
DST dystonin 0.27687
MLX MLX, MAX dimerization protein 0.27687
LACTB lactamase, beta 0.264077
SPAG7 sperm associated antigen 7 0.254536
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.253479
NCS1 neuronal calcium sensor 1 0.244345
KRT81 keratin 81, type II 0.243645
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.243295
CHAD chondroadherin 0.241546
AMBP alpha-1-microglobulin/bikunin precursor 0.241546
BSN bassoon presynaptic cytomatrix protein 0.23945
HAND1 heart and neural crest derivatives expressed 1 0.239101
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.239101
MRC1 mannose receptor, C type 1 0.236312
THAP1 THAP domain containing, apoptosis associated protein 1 0.235268
FAP fibroblast activation protein, alpha 0.230409
MGAM maltase-glucoamylase 0.225917
CRBN cereblon 0.222822
PCP2 Purkinje cell protein 2 0.218715
DMRTA1 DMRT-like family A1 0.215992
ALPPL2 alkaline phosphatase, placental-like 2 0.215653
ALPP alkaline phosphatase, placental 0.215314
ALPL alkaline phosphatase, liver/bone/kidney 0.214975
IGLV5-52 immunoglobulin lambda variable 5-52 0.197099
ALLC allantoicase 0.195183
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.191408
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.191097
GCH1 GTP cyclohydrolase 1 0.190786
NTS neurotensin 0.189859
C1QA complement component 1, q subcomponent, A chain 0.187415
LCK LCK proto-oncogene, Src family tyrosine kinase 0.17896
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.174354
NTF3 neurotrophin 3 0.173571
WFS1 Wolfram syndrome 1 (wolframin) 0.172544
WDFY2 WD repeat and FYVE domain containing 2 0.171785
ANXA3 annexin A3 0.166319
PTH parathyroid hormone 0.166095
FOS FBJ murine osteosarcoma viral oncogene homolog 0.165874
SLC22A18 solute carrier family 22, member 18 0.161716
LPIN1 lipin 1 0.159124
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.159124
LHB luteinizing hormone beta polypeptide 0.158778
B2M beta-2-microglobulin 0.157929
RPIA ribose 5-phosphate isomerase A 0.144606
LCAT lecithin-cholesterol acyltransferase 0.141914
CD27 CD27 molecule 0.141024
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.140968
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 0.140904
GGT2 gamma-glutamyltransferase 2 0.140325
SCN10A sodium channel, voltage gated, type X alpha subunit 0.139654
NF1 neurofibromin 1 0.138745
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.138733
ADAR adenosine deaminase, RNA-specific 0.138019
IGLL5 immunoglobulin lambda-like polypeptide 5 0.137573
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.137476
GPI glucose-6-phosphate isomerase 0.136016
RIPK4 receptor-interacting serine-threonine kinase 4 0.134262
PPT1 palmitoyl-protein thioesterase 1 0.130048
GGT1 gamma-glutamyltransferase 1 0.129613
FGB fibrinogen beta chain 0.129483
ADGRV1 adhesion G protein-coupled receptor V1 0.129111
ANO1 anoctamin 1, calcium activated chloride channel 0.125952
LDHC lactate dehydrogenase C 0.125354
NUMBL numb homolog (Drosophila)-like 0.123076
GPANK1 G patch domain and ankyrin repeats 1 0.122702
MAGEC1 melanoma antigen family C1 0.121791
LAX1 lymphocyte transmembrane adaptor 1 0.120711
WDR20 WD repeat domain 20 0.119411
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.118753
PTPRN protein tyrosine phosphatase, receptor type, N 0.118707
GDNF glial cell derived neurotrophic factor 0.11838
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.117838
CFP complement factor properdin 0.116857
HM13 histocompatibility (minor) 13 0.116682
ZNF135 zinc finger protein 135 0.115475
FRS2 fibroblast growth factor receptor substrate 2 0.115261
F3 coagulation factor III (thromboplastin, tissue factor) 0.114834
WARS tryptophanyl-tRNA synthetase 0.11478
TRAF3 TNF receptor-associated factor 3 0.113706
IL6 interleukin 6 0.111823
NANP N-acetylneuraminic acid phosphatase 0.111793
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa 0.11125
AOC2 amine oxidase, copper containing 2 (retina-specific) 0.11048
MYOG myogenin (myogenic factor 4) 0.110356
CALCRL calcitonin receptor-like 0.110356
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.110108
VIM vimentin 0.10979
IL1RN interleukin 1 receptor antagonist 0.10979
IFNA2 interferon, alpha 2 0.109502
AHSG alpha-2-HS-glycoprotein 0.109343
IVL involucrin 0.108431
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 0.10706
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 0.106888
SPTA1 spectrin, alpha, erythrocytic 1 0.106888
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.106715
IFT122 intraflagellar transport 122 0.106472
KRT14 keratin 14, type I 0.106126
MYOD1 myogenic differentiation 1 0.105918
NELFCD negative elongation factor complex member C/D 0.104452
FLNA filamin A, alpha 0.100521
REEP5 receptor accessory protein 5 0.100482
SP7 Sp7 transcription factor 0.100011
EWSR1 EWS RNA-binding protein 1 0.099971
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.099811
CALCR calcitonin receptor 0.09949
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.098686
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.098399
CLEC3A C-type lectin domain family 3, member A 0.098071
IBSP integrin-binding sialoprotein 0.097661
CLEC2B C-type lectin domain family 2, member B 0.097539
PRSS21 protease, serine, 21 (testisin) 0.097162
SOD2 superoxide dismutase 2, mitochondrial 0.096953
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.095517
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.095474
CARD17 caspase recruitment domain family, member 17 0.095175
CLEC10A C-type lectin domain family 10, member A 0.094919
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 0.094833
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.094703
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.094528
PENK proenkephalin 0.094441
CCL2 chemokine (C-C motif) ligand 2 0.094354
KRT86 keratin 86, type II 0.094136
TYRO3 TYRO3 protein tyrosine kinase 0.093701
NCAM1 neural cell adhesion molecule 1 0.093217
IL5 interleukin 5 0.093173
ENO2 enolase 2 (gamma, neuronal) 0.093084
CABIN1 calcineurin binding protein 1 0.092995
SREBF1 sterol regulatory element binding transcription factor 1 0.092951
HLA-A major histocompatibility complex, class I, A 0.092862
EDNRB endothelin receptor type B 0.092507
AMD1 adenosylmethionine decarboxylase 1 0.092374
MPO myeloperoxidase 0.092241
PARP1 poly (ADP-ribose) polymerase 1 0.092197
LPO lactoperoxidase 0.091295
ECI1 enoyl-CoA delta isomerase 1 0.090799
TRO trophinin 0.090617
ANPEP alanyl (membrane) aminopeptidase 0.090571
TYR tyrosinase 0.090111
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.089744