autoimmune lymphoproliferative syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. (Human Disease Ontology, DOID_6688)
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Genes

48 genes co-occuring with the disease autoimmune lymphoproliferative syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.18023
FASLG Fas ligand (TNF superfamily, member 6) 1.64621
NT5C 5', 3'-nucleotidase, cytosolic 1.5304
CD4 CD4 molecule 1.48823
SH2D1A SH2 domain containing 1A 1.46144
TRAC T cell receptor alpha constant 1.30969
FADD Fas (TNFRSF6)-associated via death domain 1.24341
FAS Fas cell surface death receptor 1.24037
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.2382
PRF1 perforin 1 (pore forming protein) 1.00625
PRKCD protein kinase C, delta 0.950352
UNC13D unc-13 homolog D (C. elegans) 0.820847
IL10 interleukin 10 0.72127
SHKBP1 SH3KBP1 binding protein 1 0.663578
B3GAT1 beta-1,3-glucuronyltransferase 1 0.630813
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.615529
FOXP3 forkhead box P3 0.583163
EOMES eomesodermin 0.571107
CD28 CD28 molecule 0.569941
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.548583
AIRE autoimmune regulator 0.537344
CD5 CD5 molecule 0.50689
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.484744
GADD45G growth arrest and DNA-damage-inducible, gamma 0.479807
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.465794
HRAS Harvey rat sarcoma viral oncogene homolog 0.446935
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.43753
CD8A CD8a molecule 0.436026
KRAS Kirsten rat sarcoma viral oncogene homolog 0.419517
GADD45B growth arrest and DNA-damage-inducible, beta 0.411657
ITK IL2-inducible T-cell kinase 0.410909
TNFRSF25 tumor necrosis factor receptor superfamily, member 25 0.401572
RAB27A RAB27A, member RAS oncogene family 0.355972
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 0.338341
SPP1 secreted phosphoprotein 1 0.336876
NCAM1 neural cell adhesion molecule 1 0.332852
CD27 CD27 molecule 0.312827
CD8B CD8b molecule 0.305226
NAIP NLR family, apoptosis inhibitory protein 0.272241
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.265849
C1R complement component 1, r subcomponent 0.260184
BCL10 B-cell CLL/lymphoma 10 0.230409
CD177 CD177 molecule 0.196139
IL2 interleukin 2 0.176215
CCL21 chemokine (C-C motif) ligand 21 0.166768
BIRC2 baculoviral IAP repeat containing 2 0.163523
GADD45A growth arrest and DNA-damage-inducible, alpha 0.161331
EIF4E eukaryotic translation initiation factor 4E 0.158097