autoimmune disease of the nervous system Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

242 genes co-occuring with the disease autoimmune disease of the nervous system in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MUSK muscle, skeletal, receptor tyrosine kinase 3.05122
TTN titin 2.02748
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 2.00791
ACHE acetylcholinesterase (Yt blood group) 1.97223
BCHE butyrylcholinesterase 1.87515
RAPSN receptor-associated protein of the synapse 1.76864
CD4 CD4 molecule 1.70087
LRP4 low density lipoprotein receptor-related protein 4 1.67683
RYR1 ryanodine receptor 1 (skeletal) 1.57824
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 1.56933
OMG oligodendrocyte myelin glycoprotein 1.53921
DOK7 docking protein 7 1.49306
NMT1 N-myristoyltransferase 1 1.41665
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 1.40132
TMPO thymopoietin 1.30226
CST7 cystatin F (leukocystatin) 1.16992
FOXP3 forkhead box P3 1.14475
AIRE autoimmune regulator 1.12825
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.12783
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 1.09167
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 1.08747
AKAP12 A kinase (PRKA) anchor protein 12 1.01596
HLA-A major histocompatibility complex, class I, A 1.01512
MAG myelin associated glycoprotein 1.01343
TGFB1 transforming growth factor, beta 1 0.987693
MBP myelin basic protein 0.976323
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.967502
POMC proopiomelanocortin 0.962472
AQP4 aquaporin 4 0.94577
CD79A CD79a molecule, immunoglobulin-associated alpha 0.945354
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.919673
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase 0.847898
MB myoglobin 0.826589
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.823718
ALB albumin 0.823308
IL4 interleukin 4 0.799923
IL2 interleukin 2 0.794181
HMGA2 high mobility group AT-hook 2 0.768801
CD5 CD5 molecule 0.761454
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.758601
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.745985
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.732191
IFNA1 interferon, alpha 1 0.726524
ADRA1D adrenoceptor alpha 1D 0.720058
CD86 CD86 molecule 0.680697
HLA-C major histocompatibility complex, class I, C 0.677903
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.67113
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.665166
CXCR5 chemokine (C-X-C motif) receptor 5 0.665166
SNRNP27 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) 0.663578
CXCL13 chemokine (C-X-C motif) ligand 13 0.655254
LTA lymphotoxin alpha 0.645375
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.624927
MYH13 myosin, heavy chain 13, skeletal muscle 0.622967
CD58 CD58 molecule 0.612792
CD80 CD80 molecule 0.59952
TNF tumor necrosis factor 0.597181
CTSV cathepsin V 0.592895
HLA-B major histocompatibility complex, class I, B 0.591337
B3GAT1 beta-1,3-glucuronyltransferase 1 0.590169
CD19 CD19 molecule 0.588222
CCL21 chemokine (C-C motif) ligand 21 0.586276
DPYSL5 dihydropyrimidinase-like 5 0.580439
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.569552
TNIP1 TNFAIP3 interacting protein 1 0.530768
ARPC5L actin related protein 2/3 complex, subunit 5-like 0.510728
IL1B interleukin 1, beta 0.505356
CAMP cathelicidin antimicrobial peptide 0.503441
C5AR1 complement component 5a receptor 1 0.499997
SCGB3A1 secretoglobin, family 3A, member 1 0.498467
CD276 CD276 molecule 0.490454
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.487407
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.482464
CD59 CD59 molecule, complement regulatory protein 0.481325
RPS13 ribosomal protein S13 0.476772
PRF1 perforin 1 (pore forming protein) 0.475634
TSPO translocator protein (18kDa) 0.461639
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.456732
CD40 CD40 molecule, TNF receptor superfamily member 5 0.454847
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.45447
MYF6 myogenic factor 6 (herculin) 0.453716
CNTNAP2 contactin associated protein-like 2 0.450701
DYNLT1 dynein, light chain, Tctex-type 1 0.448441
IL10 interleukin 10 0.446182
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.445805
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.438658
CHAT choline O-acetyltransferase 0.42289
NCAM1 neural cell adhesion molecule 1 0.421016
CD40LG CD40 ligand 0.417644
PRSS16 protease, serine, 16 (thymus) 0.414276
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.410909
MOG myelin oligodendrocyte glycoprotein 0.405678
CD69 CD69 molecule 0.404184
TRAC T cell receptor alpha constant 0.396353
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.392629
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.389653
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.389281
MYOG myogenin (myogenic factor 4) 0.382966
SNED1 sushi, nidogen and EGF-like domains 1 0.382594
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.377031
AGRN agrin 0.372587
INPP5J inositol polyphosphate-5-phosphatase J 0.369628
ICAM1 intercellular adhesion molecule 1 0.367779
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.36704
LGI1 leucine-rich, glioma inactivated 1 0.366301
ADRB2 adrenoceptor beta 2, surface 0.364085
SYT1 synaptotagmin I 0.355972
TG thyroglobulin 0.35082
CA3 carbonic anhydrase III 0.350084
SIGLEC7 sialic acid binding Ig-like lectin 7 0.344941
VPREB1 pre-B lymphocyte 1 0.339806
HSPG2 heparan sulfate proteoglycan 2 0.337975
PHYH phytanoyl-CoA 2-hydroxylase 0.33651
TCHH trichohyalin 0.33066
HLA-E major histocompatibility complex, class I, E 0.330295
MYOD1 myogenic differentiation 1 0.32701
TMX1 thioredoxin-related transmembrane protein 1 0.324458
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.318999
GOLIM4 golgi integral membrane protein 4 0.308842
C4A complement component 4A (Rodgers blood group) 0.305948
CIC capicua transcriptional repressor 0.305226
SZRD1 SUZ RNA binding domain containing 1 0.305226
IGHV3-30 immunoglobulin heavy variable 3-30 0.304142
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.299092
OAT ornithine aminotransferase 0.295851
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.294413
PTPRD protein tyrosine phosphatase, receptor type, D 0.28831
IL7R interleukin 7 receptor 0.287593
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.287593
AFP alpha-fetoprotein 0.285802
AKAP1 A kinase (PRKA) anchor protein 1 0.28294
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.28294
NRG4 neuregulin 4 0.279724
SIL1 SIL1 nucleotide exchange factor 0.276158
AMPD1 adenosine monophosphate deaminase 1 0.273664
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C 0.264785
C3 complement component 3 0.264077
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.261952
IL2RA interleukin 2 receptor, alpha 0.261245
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.257358
PANX2 pannexin 2 0.250663
PGA3 pepsinogen 3, group I (pepsinogen A) 0.24996
PGA4 pepsinogen 4, group I (pepsinogen A) 0.24996
BRDT bromodomain, testis-specific 0.247501
RND1 Rho family GTPase 1 0.246799
TSHR thyroid stimulating hormone receptor 0.246098
CLEC4C C-type lectin domain family 4, member C 0.243645
IFNB1 interferon, beta 1, fibroblast 0.237706
GFER growth factor, augmenter of liver regeneration 0.23666
WAC WW domain containing adaptor with coiled-coil 0.236312
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.225917
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.22145
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.220081
PXDN peroxidasin 0.218034
SCO1 SCO1 cytochrome c oxidase assembly protein 0.215314
NELFCD negative elongation factor complex member C/D 0.211261
RBP3 retinol binding protein 3, interstitial 0.205916
STIM1 stromal interaction molecule 1 0.205585
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.203933
NRG2 neuregulin 2 0.202946
TPM1 tropomyosin 1 (alpha) 0.202618
TFRC transferrin receptor 0.201962
IL6 interleukin 6 0.200656
PTPRC protein tyrosine phosphatase, receptor type, C 0.199033
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.197099
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.196779
NLE1 notchless homolog 1 (Drosophila) 0.19582
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.190786
TUBB2A tubulin, beta 2A class IIa 0.188632
MBD5 methyl-CpG binding domain protein 5 0.184128
F8 coagulation factor VIII, procoagulant component 0.183835
F3 coagulation factor III (thromboplastin, tissue factor) 0.182666
ST5 suppression of tumorigenicity 5 0.178403
MRPS7 mitochondrial ribosomal protein S7 0.177576
CXCR3 chemokine (C-X-C motif) receptor 3 0.177301
CTTN cortactin 0.176485
CENPC centromere protein C 0.173314
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.173057
ALLC allantoicase 0.172291
ADA adenosine deaminase 0.171036
MIR185 microRNA 185 0.170054
CNTFR ciliary neurotrophic factor receptor 0.169571
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.16933
IL18 interleukin 18 0.168148
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.168148
CNTN2 contactin 2 (axonal) 0.166768
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1 0.166095
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.165655
CD52 CD52 molecule 0.163317
TUBB tubulin, beta class I 0.163317
NFASC neurofascin 0.162306
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.161716
SST somatostatin 0.161716
CCR2 chemokine (C-C motif) receptor 2 0.161331
CIITA class II, major histocompatibility complex, transactivator 0.161331
SRPR signal recognition particle receptor (docking protein) 0.159302
IL17A interleukin 17A 0.159124
IGHV3-9 immunoglobulin heavy variable 3-9 0.158778
NUMBL numb homolog (Drosophila)-like 0.158097
MMP3 matrix metallopeptidase 3 0.157765
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.155719
THEM4 thioesterase superfamily member 4 0.153453
C5 complement component 5 0.150509
HCRT hypocretin (orexin) neuropeptide precursor 0.148854
SELL selectin L 0.146223
IAPP islet amyloid polypeptide 0.144895
SPTB spectrin, beta, erythrocytic 0.144478
CLDN5 claudin 5 0.14403
SUMF2 sulfatase modifying factor 2 0.143978
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.143912
GALE UDP-galactose-4-epimerase 0.143749
NCF1C neutrophil cytosolic factor 1C pseudogene 0.143748
NGF nerve growth factor (beta polypeptide) 0.143686
EPHA2 EPH receptor A2 0.143679
NCF1 neutrophil cytosolic factor 1 0.143438
NTF3 neurotrophin 3 0.143236
GPC3 glypican 3 0.142775
MPZ myelin protein zero 0.142135
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1 0.142099
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.142073
SNCB synuclein, beta 0.141752
CPN1 carboxypeptidase N, polypeptide 1 0.140209
GYPC glycophorin C (Gerbich blood group) 0.140127
NEFH neurofilament, heavy polypeptide 0.139911
PNMA2 paraneoplastic Ma antigen 2 0.139051
CTSA cathepsin A 0.138252
RRM1 ribonucleotide reductase M1 0.136552
GALC galactosylceramidase 0.135815
CCR1 chemokine (C-C motif) receptor 1 0.134418
CLU clusterin 0.134008
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.132899
CD46 CD46 molecule, complement regulatory protein 0.132631
FASLG Fas ligand (TNF superfamily, member 6) 0.13254
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.130895
ARSA arylsulfatase A 0.130706
PMP22 peripheral myelin protein 22 0.122961
CBS cystathionine-beta-synthase 0.117026
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.115036
BAG6 BCL2-associated athanogene 6 0.102636
MTX1 metaxin 1 0.102147
IGLV9-49 immunoglobulin lambda variable 9-49 0.101999
BIN3 bridging integrator 3 0.10195