autoimmune disease of gastrointestinal tract Gene Set

Dataset DISEASES Experimental Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypersensitivity reaction type II disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the gastrointestinal tract. (Human Disease Ontology, DOID_0060031)
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Genes

87 genes associated with the disease autoimmune disease of gastrointestinal tract in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 3.31608
LPP LIM domain containing preferred translocation partner in lipoma 2.04444
ATXN2 ataxin 2 1.40682
OLIG3 oligodendrocyte transcription factor 3 1.30954
RGS1 regulator of G-protein signaling 1 1.22898
CCR3 chemokine (C-C motif) receptor 3 1.2206
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 1.11998
IL18RAP interleukin 18 receptor accessory protein 1.09588
TAGAP T-cell activation RhoGTPase activating protein 1.06123
IL21 interleukin 21 1.02486
PTPRK protein tyrosine phosphatase, receptor type, K 0.995303
SH2B3 SH2B adaptor protein 3 0.968307
IL18R1 interleukin 18 receptor 1 0.932337
PUS10 pseudouridylate synthase 10 0.923046
KIAA1109 KIAA1109 0.894262
SLC9A4 solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4 0.790827
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.752991
RUNX3 runt-related transcription factor 3 0.69843
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.69843
PTPN2 protein tyrosine phosphatase, non-receptor type 2 0.682635
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.670996
ZMIZ1 zinc finger, MIZ-type containing 1 0.63666
IL12A interleukin 12A 0.63207
ICOSLG inducible T-cell co-stimulator ligand 0.602429
MMEL1 membrane metallo-endopeptidase-like 1 0.58494
CCR4 chemokine (C-C motif) receptor 4 0.58494
C1ORF106 chromosome 1 open reading frame 106 0.572184
ICOS inducible T-cell co-stimulator 0.552621
PLEK pleckstrin 0.537125
ARHGAP31 Rho GTPase activating protein 31 0.537125
RMI2 RecQ mediated genome instability 2 0.464771
XCR1 chemokine (C motif) receptor 1 0.438544
LRRC2 leucine rich repeat containing 2 0.429338
TMSB4X thymosin beta 4, X-linked 0.429338
PARK7 parkinson protein 7 0.408752
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.403461
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.403461
NFIA nuclear factor I/A 0.403461
LTF lactotransferrin 0.403461
IL2 interleukin 2 0.403461
CD247 CD247 molecule 0.403461
YDJC YdjC homolog (bacterial) 0.368757
ELMO1 engulfment and cell motility 1 0.368757
FRMD4B FERM domain containing 4B 0.368757
CCR2 chemokine (C-C motif) receptor 2 0.345945
BRAP BRCA1 associated protein 0.345945
MYNN myoneurin 0.345945
HECA headcase homolog (Drosophila) 0.327313
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4 0.327313
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 0.297866
DLEU1 deleted in lymphocytic leukemia 1 (non-protein coding) 0.285417
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.285417
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 0.274608
LRRIQ4 leucine-rich repeats and IQ motif containing 4 0.264872
SOX6 SRY (sex determining region Y)-box 6 0.264872
PLXNA4 plexin A4 0.256228
ZNF639 zinc finger protein 639 0.256228
FYCO1 FYVE and coiled-coil domain containing 1 0.256228
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.256228
XPO1 exportin 1 0.256228
WNT3 wingless-type MMTV integration site family, member 3 0.256228
TTC34 tetratricopeptide repeat domain 34 0.256228
NAA25 N(alpha)-acetyltransferase 25, NatB auxiliary subunit 0.197766
SCHIP1 schwannomin interacting protein 1 0.197766
DCC DCC netrin 1 receptor 0.197766
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.197766
USP34 ubiquitin specific peptidase 34 0.197766
AJAP1 adherens junctions associated protein 1 0.197766
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.197766
TG thyroglobulin 0.15771
CUX2 cut-like homeobox 2 0.15771
C6ORF99 chromosome 6 open reading frame 99 0.15771
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 0.15771
ALPK2 alpha-kinase 2 0.126165
ZFP36L1 ZFP36 ring finger protein-like 1 0.126165
C15ORF39 chromosome 15 open reading frame 39 0.126165
NCALD neurocalcin delta 0.126165
IL1RL1 interleukin 1 receptor-like 1 0.100789
AMY1A amylase, alpha 1A (salivary) 0.100789
IRF4 interferon regulatory factor 4 0.100789
CRH corticotropin releasing hormone 0.100789
CD274 CD274 molecule 0.080593
CD80 CD80 molecule 0.052255
SPANXN3 SPANX family, member N3 0.052255
TIMMDC1 translocase of inner mitochondrial membrane domain containing 1 0.052255
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 0.052255
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 0.043246