autoimmune disease of cardiovascular system Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypersensitivity reaction type II disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the cardiovascular system. (Human Disease Ontology, DOID_0060051)
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Genes

103 genes co-occuring with the disease autoimmune disease of cardiovascular system in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 1.72912
TRIM39-RPP21 TRIM39-RPP21 readthrough 1.21219
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 1.18798
RNF39 ring finger protein 39 1.18798
TRIM39 tripartite motif containing 39 1.15112
TXK TXK tyrosine kinase 1.14263
MICA MHC class I polypeptide-related sequence A 1.07992
HLA-E major histocompatibility complex, class I, E 0.982215
CRP C-reactive protein, pentraxin-related 0.980531
HLA-C major histocompatibility complex, class I, C 0.97002
SAG S-antigen; retina and pineal gland (arrestin) 0.941196
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.891718
HLA-A major histocompatibility complex, class I, A 0.891308
TNF tumor necrosis factor 0.886799
CD4 CD4 molecule 0.854859
MTCH1 mitochondrial carrier 1 0.830279
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.825768
MEFV Mediterranean fever 0.820437
DEFB106B defensin, beta 106B 0.796642
MICB MHC class I polypeptide-related sequence B 0.734217
MRAP melanocortin 2 receptor accessory protein 0.689893
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.684292
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.644586
CYTH1 cytohesin 1 0.575772
CD79A CD79a molecule, immunoglobulin-associated alpha 0.574994
IL31RA interleukin 31 receptor A 0.572273
IFNA1 interferon, alpha 1 0.55518
RORC RAR-related orphan receptor C 0.544705
DEFA1B defensin, alpha 1B 0.510728
DEFA1 defensin, alpha 1 0.510728
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.504973
DYNLT1 dynein, light chain, Tctex-type 1 0.488549
TREM1 triggering receptor expressed on myeloid cells 1 0.487027
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.472604
GIMAP2 GTPase, IMAP family member 2 0.460506
HSF2 heat shock transcription factor 2 0.459751
CCR6 chemokine (C-C motif) receptor 6 0.459751
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.458241
RBP3 retinol binding protein 3, interstitial 0.458241
TLR2 toll-like receptor 2 0.448817
IL33 interleukin 33 0.446182
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.444676
RIMS1 regulating synaptic membrane exocytosis 1 0.440914
PROS1 protein S (alpha) 0.435275
CD69 CD69 molecule 0.419892
SELE selectin E 0.402692
CXCR3 chemokine (C-X-C motif) receptor 3 0.398216
LTA lymphotoxin alpha 0.388166
NOD1 nucleotide-binding oligomerization domain containing 1 0.384451
PON1 paraoxonase 1 0.373698
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.368518
PNKD paroxysmal nonkinesigenic dyskinesia 0.360026
APOH apolipoprotein H (beta-2-glycoprotein I) 0.359289
TLR4 toll-like receptor 4 0.35082
IL6 interleukin 6 0.345308
HLA-F major histocompatibility complex, class I, F 0.342372
HCG4P11 HLA complex group 4 pseudogene 11 0.342372
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.333949
IL12RB2 interleukin 12 receptor, beta 2 0.328469
CD40 CD40 molecule, TNF receptor superfamily member 5 0.307033
ENO1 enolase 1, (alpha) 0.305587
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) 0.305226
F5 coagulation factor V (proaccelerin, labile factor) 0.301976
IL1RN interleukin 1 receptor antagonist 0.301615
TGFBR3 transforming growth factor, beta receptor III 0.297651
F2 coagulation factor II (thrombin) 0.294413
CXCR1 chemokine (C-X-C motif) receptor 1 0.27794
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.27687
GIMAP1 GTPase, IMAP family member 1 0.275801
SUMO4 small ubiquitin-like modifier 4 0.272241
CREG1 cellular repressor of E1A-stimulated genes 1 0.270464
HSH2D hematopoietic SH2 domain containing 0.266558
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.263014
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.254888
TNIP1 TNFAIP3 interacting protein 1 0.248554
ICAM1 intercellular adhesion molecule 1 0.246448
IL17A interleukin 17A 0.244345
HLA-G major histocompatibility complex, class I, G 0.226952
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.222822
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.218715
ELANE elastase, neutrophil expressed 0.217012
HLA-DMA major histocompatibility complex, class II, DM alpha 0.216672
TLR8 toll-like receptor 8 0.207912
NPTXR neuronal pentraxin receptor 0.201962
EHF ets homologous factor 0.199681
CXCL8 chemokine (C-X-C motif) ligand 8 0.194232
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.194232
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 0.193285
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.190786
MASP2 mannan-binding lectin serine peptidase 2 0.184128
IL4 interleukin 4 0.175679
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.174881
GIMAP4 GTPase, IMAP family member 4 0.172799
HYLS1 hydrolethalus syndrome 1 0.170544
CXCR2 chemokine (C-X-C motif) receptor 2 0.169571
IL12RB1 interleukin 12 receptor, beta 1 0.168381
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.167224
LGALS9 lectin, galactoside-binding, soluble, 9 0.166995
MPO myeloperoxidase 0.166319
CST4 cystatin S 0.164149
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.161912
TBX21 T-box 21 0.161912
CD80 CD80 molecule 0.158434