autoimmune disease of blood Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A hypersensitivity reaction type II disease that is the abnormal functioning of the immune system that causes your immune system to produce antibodies or T cells against cells and/or tissues in the blood. (Human Disease Ontology, DOID_0060050)
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Genes

227 genes co-occuring with the disease autoimmune disease of blood in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
THPO thrombopoietin 1.9741
MPL MPL proto-oncogene, thrombopoietin receptor 1.58269
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) 1.56356
HP haptoglobin 1.54805
HPR haptoglobin-related protein 1.54054
CD79A CD79a molecule, immunoglobulin-associated alpha 1.51809
PIGA phosphatidylinositol glycan anchor biosynthesis, class A 1.47154
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 1.36335
PSMG3 proteasome (prosome, macropain) assembly chaperone 3 1.34897
CD4 CD4 molecule 1.32279
WRB tryptophan rich basic protein 1.28392
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13 1.26778
RHD Rh blood group, D antigen 1.16906
RHCE Rh blood group, CcEe antigens 1.1072
CD47 CD47 molecule 1.0816
F8 coagulation factor VIII, procoagulant component 1.04335
KEL Kell blood group, metallo-endopeptidase 1.02692
CD52 CD52 molecule 0.994439
SIRPA signal-regulatory protein alpha 0.992752
GPR156 G protein-coupled receptor 156 0.979268
CD5 CD5 molecule 0.975903
POU2F3 POU class 2 homeobox 3 0.95996
VWF von Willebrand factor 0.947852
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.935385
F3 coagulation factor III (thromboplastin, tissue factor) 0.904032
GYPE glycophorin E (MNS blood group) 0.899924
CD19 CD19 molecule 0.897051
NAAA N-acylethanolamine acid amidase 0.885569
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.862228
IGHV3-11 immunoglobulin heavy variable 3-11 (gene/pseudogene) 0.844621
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.842163
FOXG1 forkhead box G1 0.826178
CD40LG CD40 ligand 0.813462
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.812642
IFNA2 interferon, alpha 2 0.811411
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.788852
CHAD chondroadherin 0.759416
IGHV4-59 immunoglobulin heavy variable 4-59 0.757378
MYH9 myosin, heavy chain 9, non-muscle 0.749644
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.749237
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.748424
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 0.743141
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 0.73746
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.735838
HPSE2 heparanase 2 (inactive) 0.715618
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.711989
RHOD ras homolog family member D 0.697911
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 0.690293
FOXP3 forkhead box P3 0.689893
TBX21 T-box 21 0.687491
PKLR pyruvate kinase, liver and RBC 0.681096
GATA3 GATA binding protein 3 0.651298
IGHV4-39 immunoglobulin heavy variable 4-39 0.649718
IL18BP interleukin 18 binding protein 0.648138
APOH apolipoprotein H (beta-2-glycoprotein I) 0.643404
TRIM37 tripartite motif containing 37 0.619051
PKM pyruvate kinase, muscle 0.612401
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.606933
ALB albumin 0.606543
F2 coagulation factor II (thrombin) 0.596402
EPSTI1 epithelial stromal interaction 1 (breast) 0.594454
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.586665
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.586276
IL2 interleukin 2 0.579272
FASLG Fas ligand (TNF superfamily, member 6) 0.572273
EPB41 erythrocyte membrane protein band 4.1 0.572273
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.568386
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.56722
IFNA1 interferon, alpha 1 0.561781
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.561781
GIF gastric intrinsic factor (vitamin B synthesis) 0.560227
IFRD1 interferon-related developmental regulator 1 0.558674
SYK spleen tyrosine kinase 0.554015
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.550522
GP1BB glycoprotein Ib (platelet), beta polypeptide 0.548971
CLNS1A chloride channel, nucleotide-sensitive, 1A 0.538506
CD59 CD59 molecule, complement regulatory protein 0.535022
PLAC8 placenta-specific 8 0.534635
IGHV5-51 immunoglobulin heavy variable 5-51 0.528063
POMP proteasome maturation protein 0.524202
CD40 CD40 molecule, TNF receptor superfamily member 5 0.522273
INTS8 integrator complex subunit 8 0.521117
IL6 interleukin 6 0.506507
POMC proopiomelanocortin 0.50459
CD80 CD80 molecule 0.50459
NCAM1 neural cell adhesion molecule 1 0.499614
HLA-A major histocompatibility complex, class I, A 0.490454
IL11 interleukin 11 0.485885
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.480566
CD34 CD34 molecule 0.47753
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.476014
TBX3 T-box 3 0.474877
SIGLEC7 sialic acid binding Ig-like lectin 7 0.469576
TGFB1 transforming growth factor, beta 1 0.463149
MTSS1 metastasis suppressor 1 0.457487
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.45447
FYB FYN binding protein 0.448064
PROS1 protein S (alpha) 0.446558
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.440914
TRIAP1 TP53 regulated inhibitor of apoptosis 1 0.439786
WAS Wiskott-Aldrich syndrome 0.436778
GP1BA glycoprotein Ib (platelet), alpha polypeptide 0.434524
PNP purine nucleoside phosphorylase 0.433397
IL4 interleukin 4 0.430768
RNF112 ring finger protein 112 0.428516
HLA-C major histocompatibility complex, class I, C 0.425514
C3 complement component 3 0.425139
IL10 interleukin 10 0.412031
KRT83 keratin 83, type II 0.409787
CD38 CD38 molecule 0.393001
IL2RA interleukin 2 receptor, alpha 0.391885
GRB2 growth factor receptor-bound protein 2 0.376661
GCH1 GTP cyclohydrolase 1 0.375179
MIR186 microRNA 186 0.369258
CD163 CD163 molecule 0.368149
C1S complement component 1, s subcomponent 0.361502
GYPA glycophorin A (MNS blood group) 0.360026
DEFA3 defensin, alpha 3, neutrophil-specific 0.357446
IGH immunoglobulin heavy locus 0.350084
IGHV1-69 immunoglobulin heavy variable 1-69 0.348981
PFDN4 prefoldin subunit 4 0.347879
CLEC3A C-type lectin domain family 3, member A 0.346042
CLEC2B C-type lectin domain family 2, member B 0.341272
STIM1 stromal interaction molecule 1 0.339806
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 0.332487
CT45A1 cancer/testis antigen family 45, member A1 0.325187
IGHV3-21 immunoglobulin heavy variable 3-21 0.323365
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.319363
CLEC10A C-type lectin domain family 10, member A 0.318635
CD96 CD96 molecule 0.316092
PF4 platelet factor 4 0.312102
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 0.310652
PRMT2 protein arginine methyltransferase 2 0.298731
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.296211
ACPP acid phosphatase, prostate 0.287593
IL18 interleukin 18 0.285086
GP9 glycoprotein IX (platelet) 0.281153
G6PD glucose-6-phosphate dehydrogenase 0.278297
GYPC glycophorin C (Gerbich blood group) 0.272241
CTPS1 CTP synthase 1 0.271886
ALPPL2 alkaline phosphatase, placental-like 2 0.268687
ALPP alkaline phosphatase, placental 0.268332
ALPL alkaline phosphatase, liver/bone/kidney 0.267977
DNASE1L3 deoxyribonuclease I-like 3 0.267622
EPO erythropoietin 0.264431
IFI27 interferon, alpha-inducible protein 27 0.257711
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.255946
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.255594
CD79B CD79b molecule, immunoglobulin-associated beta 0.253479
IGLV9-49 immunoglobulin lambda variable 9-49 0.248905
IFNG interferon, gamma 0.245396
SBF2 SET binding factor 2 0.243645
TFRC transferrin receptor 0.242245
CD69 CD69 molecule 0.239799
GATA2 GATA binding protein 2 0.234225
RAN RAN, member RAS oncogene family 0.230063
CD36 CD36 molecule (thrombospondin receptor) 0.225229
TCN2 transcobalamin II 0.224884
DPT dermatopontin 0.223853
CCNC cyclin C 0.222822
CRP C-reactive protein, pentraxin-related 0.218715
CD86 CD86 molecule 0.217352
MBD1 methyl-CpG binding domain protein 1 0.209918
KRT84 keratin 84, type II 0.205585
IL3 interleukin 3 0.204923
IDS iduronate 2-sulfatase 0.202618
B2M beta-2-microglobulin 0.20229
TNF tumor necrosis factor 0.200656
IGKV3-20 immunoglobulin kappa variable 3-20 0.200331
GP6 glycoprotein VI (platelet) 0.194548
KAT8 K(lysine) acetyltransferase 8 0.192971
BCAM basal cell adhesion molecule (Lutheran blood group) 0.192031
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.191408
PTPRC protein tyrosine phosphatase, receptor type, C 0.190476
HOXB4 homeobox B4 0.185612
SH2D1A SH2 domain containing 1A 0.183248
THBD thrombomodulin 0.18151
IL2RB interleukin 2 receptor, beta 0.180084
B3GAT1 beta-1,3-glucuronyltransferase 1 0.166319
OAT ornithine aminotransferase 0.166095
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.165435
INSC inscuteable homolog (Drosophila) 0.164571
TINF2 TERF1 (TRF1)-interacting nuclear factor 2 0.161912
CD72 CD72 molecule 0.161523
UST uronyl-2-sulfotransferase 0.161523
AIRE autoimmune regulator 0.161139
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.158299
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.157765
SH3BP2 SH3-domain binding protein 2 0.141116
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.141074
IL1RN interleukin 1 receptor antagonist 0.140887
CYS1 cystin 1 0.140193
LCK LCK proto-oncogene, Src family tyrosine kinase 0.140032
BCO1 beta-carotene oxygenase 1 0.139921
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 0.139652
UBIAD1 UbiA prenyltransferase domain containing 1 0.139481
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5 0.139475
AGO2 argonaute RISC catalytic component 2 0.139251
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.139244
MT3 metallothionein 3 0.139039
FKBP5 FK506 binding protein 5 0.138644
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.13844
PDLIM7 PDZ and LIM domain 7 (enigma) 0.133088
DGAT1 diacylglycerol O-acyltransferase 1 0.132003
CFAP74 cilia and flagella associated protein 74 0.131519
MIR19A microRNA 19a 0.131013
IFNB1 interferon, beta 1, fibroblast 0.130499
LCA10 lung carcinoma-associated 10 0.130363
PREB prolactin regulatory element binding 0.130124
IL6R interleukin 6 receptor 0.130064
RAG2 recombination activating gene 2 0.130064
BST2 bone marrow stromal cell antigen 2 0.129291
DHCR24 24-dehydrocholesterol reductase 0.127204
RGMA repulsive guidance molecule family member a 0.126738
CYCS cytochrome c, somatic 0.126711
C5 complement component 5 0.125643
HYLS1 hydrolethalus syndrome 1 0.125329
EPOR erythropoietin receptor 0.12527
LAG3 lymphocyte-activation gene 3 0.125034
ORAI1 ORAI calcium release-activated calcium modulator 1 0.124646
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.124059
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 0.12387
CSF3 colony stimulating factor 3 (granulocyte) 0.121815
CP ceruloplasmin (ferroxidase) 0.121599
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.118272
CD22 CD22 molecule 0.118187
ISG20 interferon stimulated exonuclease gene 20kDa 0.117933