auditory vesicle Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The saccular invagination of ectoderm from which the vertebrate inner ear develops. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002661)
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Genes

308 proteins co-occuring with the tissue auditory vesicle in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FGF3 fibroblast growth factor 3 1.99428
FOXI1 forkhead box I1 1.94096
HMX3 H6 family homeobox 3 1.8399
EYA1 EYA transcriptional coactivator and phosphatase 1 1.62806
DAW1 dynein assembly factor with WDR repeat domains 1 1.6146
PAX2 paired box 2 1.60713
OTOL1 otolin 1 1.46821
FGF8 fibroblast growth factor 8 (androgen-induced) 1.43107
PAX8 paired box 8 1.40018
TBX1 T-box 1 1.36222
GBX2 gastrulation brain homeobox 2 1.34587
CYP26C1 cytochrome P450, family 26, subfamily C, polypeptide 1 1.32371
LINGO3 leucine rich repeat and Ig domain containing 3 1.30523
SOX10 SRY (sex determining region Y)-box 10 1.29399
OTX1 orthodenticle homeobox 1 1.28681
FGF10 fibroblast growth factor 10 1.26799
HOXB1 homeobox B1 1.2671
RFX7 regulatory factor X, 7 1.24342
DTX4 deltex 4, E3 ubiquitin ligase 1.24163
PRELID2 PRELI domain containing 2 1.23628
DLX3 distal-less homeobox 3 1.22871
PCDH18 protocadherin 18 1.22425
LRIG3 leucine-rich repeats and immunoglobulin-like domains 3 1.2238
FAM92A1 family with sequence similarity 92, member A1 1.22291
LRRTM1 leucine rich repeat transmembrane neuronal 1 1.22202
SIX1 SIX homeobox 1 1.19356
RFX2 regulatory factor X, 2 (influences HLA class II expression) 1.19223
TTC25 tetratricopeptide repeat domain 25 1.18468
DONSON downstream neighbor of SON 1.18334
SALL3 spalt-like transcription factor 3 1.13545
DNAAF1 dynein, axonemal, assembly factor 1 1.10447
GSC goosecoid homeobox 1.09474
EYA4 EYA transcriptional coactivator and phosphatase 4 1.08457
BMP4 bone morphogenetic protein 4 1.07839
LRRTM4 leucine rich repeat transmembrane neuronal 4 1.07265
DLX5 distal-less homeobox 5 1.0603
MNX1 motor neuron and pancreas homeobox 1 1.04752
PTP4A2 protein tyrosine phosphatase type IVA, member 2 1.04752
LGR6 leucine-rich repeat containing G protein-coupled receptor 6 1.04445
TBX2 T-box 2 1.04005
ATOH1 atonal homolog 1 (Drosophila) 1.03785
COL11A1 collagen, type XI, alpha 1 1.02732
COL2A1 collagen, type II, alpha 1 1.02557
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 1.01418
LINGO2 leucine rich repeat and Ig domain containing 2 1.00109
NOG noggin 0.986294
PCSK5 proprotein convertase subtilisin/kexin type 5 0.983688
OTX2 orthodenticle homeobox 2 0.983254
VGLL1 vestigial-like family member 1 0.975882
LECT1 leukocyte cell derived chemotaxin 1 0.970253
SOX9 SRY (sex determining region Y)-box 9 0.952978
PCDH1 protocadherin 1 0.949531
POU3F4 POU class 3 homeobox 4 0.948239
CELF3 CUGBP, Elav-like family member 3 0.940925
VGLL4 vestigial-like family member 4 0.930621
LRRTM3 leucine rich repeat transmembrane neuronal 3 0.923767
DBX2 developing brain homeobox 2 0.921627
SHH sonic hedgehog 0.920771
SNIP1 Smad nuclear interacting protein 1 0.919916
COL5A3 collagen, type V, alpha 3 0.919061
PCDH8 protocadherin 8 0.898595
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.886286
BMPER BMP binding endothelial regulator 0.874016
RHOA ras homolog family member A 0.870217
DLX4 distal-less homeobox 4 0.866842
FREM3 FRAS1 related extracellular matrix 3 0.86642
FOXI2 forkhead box I2 0.863048
OTOG otogelin 0.857153
HOXD4 homeobox D4 0.857153
MSX1 msh homeobox 1 0.856732
FOXG1 forkhead box G1 0.854209
PCDH11Y protocadherin 11 Y-linked 0.852527
PCDH11X protocadherin 11 X-linked 0.838252
CHRD chordin 0.835318
PCGF1 polycomb group ring finger 1 0.832804
NGF nerve growth factor (beta polypeptide) 0.832804
WNT1 wingless-type MMTV integration site family, member 1 0.829034
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.823594
WNT3A wingless-type MMTV integration site family, member 3A 0.823175
PRELID1 PRELI domain containing 1 0.818994
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.817322
PCDH19 protocadherin 19 0.813562
SCUBE3 signal peptide, CUB domain, EGF-like 3 0.813144
LRRTM2 leucine rich repeat transmembrane neuronal 2 0.812309
DACH1 dachshund family transcription factor 1 0.811473
SLC2A4RG SLC2A4 regulator 0.810638
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10 0.808134
SMC4 structural maintenance of chromosomes 4 0.800208
DZIP1 DAZ interacting zinc finger protein 1 0.798958
FRMD7 FERM domain containing 7 0.798541
OTOP1 otopetrin 1 0.797708
MYO7A myosin VIIA 0.793543
POU3F2 POU class 3 homeobox 2 0.791044
HMX2 H6 family homeobox 2 0.785635
TSPAN3 tetraspanin 3 0.779401
HOXB3 homeobox B3 0.778155
GINS4 GINS complex subunit 4 (Sld5 homolog) 0.776494
LZTS2 leucine zipper, putative tumor suppressor 2 0.774004
SYNJ2BP synaptojanin 2 binding protein 0.773174
FOXK2 forkhead box K2 0.772344
AGR3 anterior gradient 3 0.766539
DACH2 dachshund family transcription factor 2 0.765296
OTOR otoraplin 0.762811
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.761155
NEUROD1 neuronal differentiation 1 0.760742
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.75371
MAB21L1 mab-21-like 1 (C. elegans) 0.75247
ZNF395 zinc finger protein 395 0.750405
HOXB5 homeobox B5 0.749166
JAG1 jagged 1 0.742976
POU4F3 POU class 4 homeobox 3 0.74009
RFX4 regulatory factor X, 4 (influences HLA class II expression) 0.728152
LRRN1 leucine rich repeat neuronal 1 0.725685
PTCH1 patched 1 0.7146
FGF1 fibroblast growth factor 1 (acidic) 0.70968
MAB21L2 mab-21-like 2 (C. elegans) 0.70968
ARID5B AT rich interactive domain 5B (MRF1-like) 0.706402
ISM1 isthmin 1, angiogenesis inhibitor 0.696172
RGS18 regulator of G-protein signaling 18 0.695763
MKX mohawk homeobox 0.690451
SMC2 structural maintenance of chromosomes 2 0.688409
AGR2 anterior gradient 2 0.68188
SIX4 SIX homeobox 4 0.674135
FOXK1 forkhead box K1 0.672913
HMX1 H6 family homeobox 1 0.670878
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.667622
FREM2 FRAS1 related extracellular matrix protein 2 0.665588
SALL1 spalt-like transcription factor 1 0.662336
WNT3 wingless-type MMTV integration site family, member 3 0.661523
COBL cordon-bleu WH2 repeat protein 0.649749
SMC1A structural maintenance of chromosomes 1A 0.649749
NFE2L3 nuclear factor, erythroid 2-like 3 0.641238
PAX3 paired box 3 0.639619
OPTC opticin 0.635167
COL4A6 collagen, type IV, alpha 6 0.631931
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.631527
PCDH17 protocadherin 17 0.627889
LMO3 LIM domain only 3 (rhombotin-like 2) 0.620621
PCDH7 protocadherin 7 0.6182
PCDH9 protocadherin 9 0.616183
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.61578
FOXJ1 forkhead box J1 0.615377
FOXJ2 forkhead box J2 0.60893
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.605306
HNF1B HNF1 homeobox B 0.601283
NEUROG1 neurogenin 1 0.599273
DBX1 developing brain homeobox 1 0.598871
NTN1 netrin 1 0.59124
FRAS1 Fraser extracellular matrix complex subunit 1 0.590839
FGFR2 fibroblast growth factor receptor 2 0.590437
HOXA1 homeobox A1 0.586828
CELF4 CUGBP, Elav-like family member 4 0.58242
FGFR1 fibroblast growth factor receptor 1 0.580818
KIDINS220 kinase D-interacting substrate, 220kDa 0.576415
MMP8 matrix metallopeptidase 8 0.576415
IGF1 insulin-like growth factor 1 (somatomedin C) 0.562042
HNF4A hepatocyte nuclear factor 4, alpha 0.561644
RLN1 relaxin 1 0.560847
WNT8A wingless-type MMTV integration site family, member 8A 0.557661
SIX2 SIX homeobox 2 0.549709
GPC4 glypican 4 0.546136
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4 0.544152
SIX3 SIX homeobox 3 0.535438
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.53346
RAB40AL RAB40A, member RAS oncogene family-like 0.529903
HOXB4 homeobox B4 0.525166
MARK3 MAP/microtubule affinity-regulating kinase 3 0.522405
RTN1 reticulon 1 0.521617
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.521223
FOXL1 forkhead box L1 0.518859
PTH2R parathyroid hormone 2 receptor 0.518465
WNT9A wingless-type MMTV integration site family, member 9A 0.516104
FOXQ1 forkhead box Q1 0.514924
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.512564
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) 0.505887
TLE4 transducin-like enhancer of split 4 0.503926
ADAM23 ADAM metallopeptidase domain 23 0.500007
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide 0.499615
HOXB6 homeobox B6 0.495309
EYA2 EYA transcriptional coactivator and phosphatase 2 0.494528
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.489057
AES amino-terminal enhancer of split 0.488667
LMO2 LIM domain only 2 (rhombotin-like 1) 0.487106
EIF6 eukaryotic translation initiation factor 6 0.487106
PLXNA4 plexin A4 0.485545
HOXB9 homeobox B9 0.484376
MEIS2 Meis homeobox 2 0.484376
NTN4 netrin 4 0.483206
PCDH10 protocadherin 10 0.481648
PAX5 paired box 5 0.481259
MYH9 myosin, heavy chain 9, non-muscle 0.478923
SULF2 sulfatase 2 0.476201
IRX1 iroquois homeobox 1 0.475034
CERK ceramide kinase 0.475034
DTX1 deltex 1, E3 ubiquitin ligase 0.474646
SCIN scinderin 0.468048
GRP gastrin-releasing peptide 0.465723
NTF4 neurotrophin 4 0.460692
WNT8B wingless-type MMTV integration site family, member 8B 0.459532
MECOM MDS1 and EVI1 complex locus 0.457214
PCGF2 polycomb group ring finger 2 0.451428
MMP15 matrix metallopeptidase 15 (membrane-inserted) 0.447961
SMC3 structural maintenance of chromosomes 3 0.447192
KLF10 Kruppel-like factor 10 0.445653
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 0.442194
ZFHX3 zinc finger homeobox 3 0.436822
DLX6 distal-less homeobox 6 0.428401
TBX4 T-box 4 0.427636
JAG2 jagged 2 0.426109
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.425726
TSPAN7 tetraspanin 7 0.423436
LMO1 LIM domain only 1 (rhombotin 1) 0.42191
ELSPBP1 epididymal sperm binding protein 1 0.416195
RBP1 retinol binding protein 1, cellular 0.413912
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.408212
TLX1 T-cell leukemia homeobox 1 0.407453
KRTAP1-3 keratin associated protein 1-3 0.406694
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.405935
HEBP1 heme binding protein 1 0.405555
ETV4 ets variant 4 0.405176
FGFR4 fibroblast growth factor receptor 4 0.404418
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.401007
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.401007
KRTAP1-1 keratin associated protein 1-1 0.399114
HAPLN1 hyaluronan and proteoglycan link protein 1 0.397222
IRX3 iroquois homeobox 3 0.396844
SOX8 SRY (sex determining region Y)-box 8 0.395709
COL5A1 collagen, type V, alpha 1 0.392309
HOXB2 homeobox B2 0.390044
ADAM28 ADAM metallopeptidase domain 28 0.379123
NOTCH1 notch 1 0.374618
CELF1 CUGBP, Elav-like family member 1 0.371245
ADAM22 ADAM metallopeptidase domain 22 0.369747
CBLN1 cerebellin 1 precursor 0.366754
COCH cochlin 0.361901
NOTCH2NL notch 2 N-terminal like 0.360782
MSX2 msh homeobox 2 0.358919
NOTCH2 notch 2 0.357802
TLX3 T-cell leukemia homeobox 3 0.352598
LHX1 LIM homeobox 1 0.351114
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.348148
CTBP2 C-terminal binding protein 2 0.344079
SMO smoothened, frizzled class receptor 0.344079
ARHGAP18 Rho GTPase activating protein 18 0.336336
RAD21 RAD21 homolog (S. pombe) 0.336336
SOX2 SRY (sex determining region Y)-box 2 0.332661
RAB11A RAB11A, member RAS oncogene family 0.33046
FZD7 frizzled class receptor 7 0.327896
LEF1 lymphoid enhancer-binding factor 1 0.326798
PLXNB1 plexin B1 0.324605
APAF1 apoptotic peptidase activating factor 1 0.322779
EVL Enah/Vasp-like 0.322414
SDC3 syndecan 3 0.319134
STARD13 StAR-related lipid transfer (START) domain containing 13 0.318407
GATA2 GATA binding protein 2 0.317315
NTF3 neurotrophin 3 0.315498
LMX1A LIM homeobox transcription factor 1, alpha 0.313683
SIX5 SIX homeobox 5 0.312595
COL4A5 collagen, type IV, alpha 5 0.308251
SP8 Sp8 transcription factor 0.306083
TGFBR1 transforming growth factor, beta receptor 1 0.303559
CRABP1 cellular retinoic acid binding protein 1 0.303559
WNT6 wingless-type MMTV integration site family, member 6 0.303198
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.300679
HOXA2 homeobox A2 0.294581
DLX1 distal-less homeobox 1 0.294223
ADAM9 ADAM metallopeptidase domain 9 0.291365
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.289939
ACVR1 activin A receptor, type I 0.289582
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.287447
PDS5B PDS5 cohesin associated factor B 0.287447
HSPB8 heat shock 22kDa protein 8 0.286381
SIL1 SIL1 nucleotide exchange factor 0.278955
WNT2B wingless-type MMTV integration site family, member 2B 0.2779
CDH4 cadherin 4, type 1, R-cadherin (retinal) 0.271952
SOX6 SRY (sex determining region Y)-box 6 0.271604
NGFR nerve growth factor receptor 0.271256
BDNF brain-derived neurotrophic factor 0.269174
PRKG1 protein kinase, cGMP-dependent, type I 0.265725
PRDM1 PR domain containing 1, with ZNF domain 0.265381
ISL1 ISL LIM homeobox 1 0.262986
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1 0.262645
IGF1R insulin-like growth factor 1 receptor 0.262304
HOXB7 homeobox B7 0.260606
POU4F2 POU class 4 homeobox 2 0.259254
CLIP1 CAP-GLY domain containing linker protein 1 0.258917
FGFR3 fibroblast growth factor receptor 3 0.250627
VCAN versican 0.247719
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.245807
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.236921
ADAM12 ADAM metallopeptidase domain 12 0.234878
MEIS1 Meis homeobox 1 0.234302
ARHGAP1 Rho GTPase activating protein 1 0.233731
PAX9 paired box 9 0.233731
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D 0.232599
RFX1 regulatory factor X, 1 (influences HLA class II expression) 0.232317
NRF1 nuclear respiratory factor 1 0.23176
FGF5 fibroblast growth factor 5 0.228234
DIO3 deiodinase, iodothyronine, type III 0.224645
SPRY3 sprouty homolog 3 (Drosophila) 0.22415
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.218613
DUSP6 dual specificity phosphatase 6 0.218186
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.218186
BMP3 bone morphogenetic protein 3 0.217554
PCSK7 proprotein convertase subtilisin/kexin type 7 0.217139
FOS FBJ murine osteosarcoma viral oncogene homolog 0.21573
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.213471
WNT7A wingless-type MMTV integration site family, member 7A 0.213112