atropine oxide-6812 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the atropine oxide-6812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APOM apolipoprotein M
ATP11A ATPase, class VI, type 11A
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
ATXN3 ataxin 3
BAIAP3 BAI1-associated protein 3
BIN1 bridging integrator 1
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CARD10 caspase recruitment domain family, member 10
CASP10 caspase 10, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CCDC132 coiled-coil domain containing 132
CD34 CD34 molecule
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH8 cadherin 8, type 2
CLDN11 claudin 11
CLDN17 claudin 17
CLGN calmegin
CLPS colipase, pancreatic
CPNE7 copine VII
CTBP2 C-terminal binding protein 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DTNA dystrobrevin, alpha
DUSP9 dual specificity phosphatase 9
EHBP1L1 EH domain binding protein 1-like 1
ETV6 ets variant 6
FBXL7 F-box and leucine-rich repeat protein 7
FGD1 FYVE, RhoGEF and PH domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
HCFC1 host cell factor C1
HNRNPM heterogeneous nuclear ribonucleoprotein M
ICOSLG inducible T-cell co-stimulator ligand
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IGFBP5 insulin-like growth factor binding protein 5
IL6R interleukin 6 receptor
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0319L KIAA0319-like
LAT2 linker for activation of T cells family, member 2
LIN7A lin-7 homolog A (C. elegans)
LOC100131532 uncharacterized LOC100131532
LRP2 low density lipoprotein receptor-related protein 2
MAPK14 mitogen-activated protein kinase 14
MC5R melanocortin 5 receptor
MED16 mediator complex subunit 16
MLANA melan-A
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRPL41 mitochondrial ribosomal protein L41
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYLK myosin light chain kinase
NIPAL3 NIPA-like domain containing 3
NOL12 nucleolar protein 12
NRP1 neuropilin 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUPR1 nuclear protein, transcriptional regulator, 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLFML2A olfactomedin-like 2A
OSGIN1 oxidative stress induced growth inhibitor 1
PAPPA2 pappalysin 2
PCDHB11 protocadherin beta 11
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PHF1 PHD finger protein 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PTHLH parathyroid hormone-like hormone
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RIMS3 regulating synaptic membrane exocytosis 3
RLN1 relaxin 1
RNF208 ring finger protein 208
RSG1 REM2 and RAB-like small GTPase 1
SECTM1 secreted and transmembrane 1
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SIK3 SIK family kinase 3
SIM2 single-minded family bHLH transcription factor 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SOCS1 suppressor of cytokine signaling 1
SPRR1B small proline-rich protein 1B
SPRY2 sprouty homolog 2 (Drosophila)
TBX5 T-box 5
TEF thyrotrophic embryonic factor
TFEB transcription factor EB
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TK2 thymidine kinase 2, mitochondrial
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TP63 tumor protein p63
TRIM38 tripartite motif containing 38
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VASH2 vasohibin 2
WNT16 wingless-type MMTV integration site family, member 16
XYLT1 xylosyltransferase I
ZCCHC24 zinc finger, CCHC domain containing 24
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BBC3 BCL2 binding component 3
BIN3 bridging integrator 3
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF70 chromosome 17 open reading frame 70
C1ORF105 chromosome 1 open reading frame 105
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK1D calcium/calmodulin-dependent protein kinase ID
CBX8 chromobox homolog 8
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CHM choroideremia (Rab escort protein 1)
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CRLF1 cytokine receptor-like factor 1
CSF1R colony stimulating factor 1 receptor
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DBF4B DBF4 zinc finger B
DEAF1 DEAF1 transcription factor
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DSCAM Down syndrome cell adhesion molecule
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EGFL7 EGF-like-domain, multiple 7
ERN1 endoplasmic reticulum to nucleus signaling 1
FBXW12 F-box and WD repeat domain containing 12
GAMT guanidinoacetate N-methyltransferase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLB1L2 galactosidase, beta 1-like 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR19 G protein-coupled receptor 19
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
GYS1 glycogen synthase 1 (muscle)
HDAC7 histone deacetylase 7
HIST2H2AA3 histone cluster 2, H2aa3
HYI hydroxypyruvate isomerase (putative)
INO80D INO80 complex subunit D
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KDM8 lysine (K)-specific demethylase 8
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
KRT15 keratin 15, type I
LHX6 LIM homeobox 6
LOC729164 hCG1732469
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MEFV Mediterranean fever
MXD3 MAX dimerization protein 3
NEK11 NIMA-related kinase 11
PADI3 peptidyl arginine deiminase, type III
PARD6A par-6 family cell polarity regulator alpha
PCBP3 poly(rC) binding protein 3
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PNPLA6 patatin-like phospholipase domain containing 6
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
RIN2 Ras and Rab interactor 2
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1A SET domain containing 1A
SH2B3 SH2B adaptor protein 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SMIM14 small integral membrane protein 14
STRA6 stimulated by retinoic acid 6
THAP7 THAP domain containing 7
TMC5 transmembrane channel-like 5
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBOX5 U-box domain containing 5
UPK3B uroplakin 3B
WDR25 WD repeat domain 25
XYLT2 xylosyltransferase II
YEATS2 YEATS domain containing 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZFP69B ZFP69 zinc finger protein B
ZNF205 zinc finger protein 205