atropine oxide-2216 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the atropine oxide-2216 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ALDOB aldolase B, fructose-bisphosphate
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
BCL6 B-cell CLL/lymphoma 6
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C10ORF12 chromosome 10 open reading frame 12
C8B complement component 8, beta polypeptide
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC87 coiled-coil domain containing 87
CD52 CD52 molecule
CD6 CD6 molecule
CDH8 cadherin 8, type 2
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CLTA clathrin, light chain A
CXCL8 chemokine (C-X-C motif) ligand 8
DGCR8 DGCR8 microprocessor complex subunit
DRD1 dopamine receptor D1
EFNB3 ephrin-B3
FAM214B family with sequence similarity 214, member B
FBXO31 F-box protein 31
FGF4 fibroblast growth factor 4
FXYD5 FXYD domain containing ion transport regulator 5
FYB FYN binding protein
GGT1 gamma-glutamyltransferase 1
GK3P glycerol kinase 3 pseudogene
GOLGA2P5 golgin A2 pseudogene 5
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HIST1H4E histone cluster 1, H4e
IL17RC interleukin 17 receptor C
IL18 interleukin 18
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KCTD12 potassium channel tetramerization domain containing 12
LCMT2 leucine carboxyl methyltransferase 2
LOC100286895 cell division cycle 27 homolog pseudogene
LRP12 low density lipoprotein receptor-related protein 12
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYZ lysozyme
MBD2 methyl-CpG binding domain protein 2
MBNL2 muscleblind-like splicing regulator 2
METTL7A methyltransferase like 7A
MLN motilin
MTCP1 mature T-cell proliferation 1
NCAPH2 non-SMC condensin II complex, subunit H2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NF2 neurofibromin 2 (merlin)
NME5 NME/NM23 family member 5
NOX1 NADPH oxidase 1
NPFF neuropeptide FF-amide peptide precursor
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP188 nucleoporin 188kDa
OCA2 oculocutaneous albinism II
OXCT2 3-oxoacid CoA transferase 2
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCBP3 poly(rC) binding protein 3
PDIA2 protein disulfide isomerase family A, member 2
PGR progesterone receptor
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PVR poliovirus receptor
RAD54L2 RAD54-like 2 (S. cerevisiae)
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOBTB2 Rho-related BTB domain containing 2
RPL10L ribosomal protein L10-like
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SEC24A SEC24 family member A
SH3BP2 SH3-domain binding protein 2
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC25A30 solute carrier family 25, member 30
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMIM14 small integral membrane protein 14
SNED1 sushi, nidogen and EGF-like domains 1
SOAT2 sterol O-acyltransferase 2
STAB1 stabilin 1
STOML1 stomatin (EPB72)-like 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRD T cell receptor delta locus
TSPAN9 tetraspanin 9
VNN2 vanin 2
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VPS9D1 VPS9 domain containing 1
YTHDC2 YTH domain containing 2
ZC3H7B zinc finger CCCH-type containing 7B
ZNF235 zinc finger protein 235
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ACBD4 acyl-CoA binding domain containing 4
ALPK1 alpha-kinase 1
APOLD1 apolipoprotein L domain containing 1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C11ORF80 chromosome 11 open reading frame 80
C5AR2 complement component 5a receptor 2
C7ORF43 chromosome 7 open reading frame 43
C9ORF9 chromosome 9 open reading frame 9
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CCDC121 coiled-coil domain containing 121
CDK20 cyclin-dependent kinase 20
CDON cell adhesion associated, oncogene regulated
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CRELD1 cysteine-rich with EGF-like domains 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGAT1 diacylglycerol O-acyltransferase 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DOK5 docking protein 5
ELSPBP1 epididymal sperm binding protein 1
ETNK2 ethanolamine kinase 2
FBXL7 F-box and leucine-rich repeat protein 7
FLJ11710 uncharacterized protein FLJ11710
FOXN2 forkhead box N2
GADD45G growth arrest and DNA-damage-inducible, gamma
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTM5 glutathione S-transferase mu 5
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H2AL histone cluster 1, H2al
HIST1H3E histone cluster 1, H3e
HIST1H4A histone cluster 1, H4a
IFNAR1 interferon (alpha, beta and omega) receptor 1
KDM8 lysine (K)-specific demethylase 8
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
KLK5 kallikrein-related peptidase 5
KRT15 keratin 15, type I
LHX1 LIM homeobox 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAST3 microtubule associated serine/threonine kinase 3
MCC mutated in colorectal cancers
METTL2B methyltransferase like 2B
MFSD11 major facilitator superfamily domain containing 11
MITF microphthalmia-associated transcription factor
MRPL41 mitochondrial ribosomal protein L41
MTA2 metastasis associated 1 family, member 2
MYOZ1 myozenin 1
NDE1 nudE neurodevelopment protein 1
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NPIPB3 nuclear pore complex interacting protein family, member B3
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PCDHGB5 protocadherin gamma subfamily B, 5
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC1 placenta-specific 1
POLL polymerase (DNA directed), lambda
PQLC2 PQ loop repeat containing 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF2 ring finger protein 2
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SIPA1 signal-induced proliferation-associated 1
SKI SKI proto-oncogene
SLC43A1 solute carrier family 43 (amino acid system L transporter), member 1
SPON2 spondin 2, extracellular matrix protein
STAB2 stabilin 2
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STRA6 stimulated by retinoic acid 6
STX1A syntaxin 1A (brain)
TBX19 T-box 19
TEX40 testis expressed 40
TMCC2 transmembrane and coiled-coil domain family 2
TNS2 tensin 2
TPST2 tyrosylprotein sulfotransferase 2
TTC33 tetratricopeptide repeat domain 33
VEGFB vascular endothelial growth factor B
WDR76 WD repeat domain 76
WNT10B wingless-type MMTV integration site family, member 10B
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF204P zinc finger protein 204, pseudogene
ZNF41 zinc finger protein 41
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747