atropine oxide-1370 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the atropine oxide-1370 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADK adenosine kinase
ANKRD36 ankyrin repeat domain 36
ASMTL acetylserotonin O-methyltransferase-like
ATF2 activating transcription factor 2
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
ATXN7 ataxin 7
AZI2 5-azacytidine induced 2
C17ORF75 chromosome 17 open reading frame 75
CCPG1 cell cycle progression 1
CD300A CD300a molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CEP152 centrosomal protein 152kDa
CHD9 chromodomain helicase DNA binding protein 9
CLCC1 chloride channel CLIC-like 1
CTSS cathepsin S
DENND4A DENN/MADD domain containing 4A
DPYD dihydropyrimidine dehydrogenase
DSCR3 Down syndrome critical region 3
DUS2 dihydrouridine synthase 2
EID1 EP300 interacting inhibitor of differentiation 1
EIF5B eukaryotic translation initiation factor 5B
ELF2 E74-like factor 2 (ets domain transcription factor)
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FASTK Fas-activated serine/threonine kinase
FLI1 Fli-1 proto-oncogene, ETS transcription factor
GCA grancalcin, EF-hand calcium binding protein
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPSM2 G-protein signaling modulator 2
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOMER1 homer scaffolding protein 1
IL1B interleukin 1, beta
ITM2B integral membrane protein 2B
KIF20B kinesin family member 20B
KLHL7 kelch-like family member 7
KRIT1 KRIT1, ankyrin repeat containing
LARP4 La ribonucleoprotein domain family, member 4
LIN7C lin-7 homolog C (C. elegans)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH2P mago-nashi homolog 2, pseudogene
MAGOHB mago-nashi homolog B (Drosophila)
MAN1B1 mannosidase, alpha, class 1B, member 1
MED7 mediator complex subunit 7
METTL7A methyltransferase like 7A
MORC3 MORC family CW-type zinc finger 3
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
MSH3 mutS homolog 3
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAPOLA poly(A) polymerase alpha
PCBP2 poly(rC) binding protein 2
PHACTR2 phosphatase and actin regulator 2
PICALM phosphatidylinositol binding clathrin assembly protein
PLAGL1 pleiomorphic adenoma gene-like 1
PLK4 polo-like kinase 4
PNISR PNN-interacting serine/arginine-rich protein
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RAB11A RAB11A, member RAS oncogene family
RAD17 RAD17 homolog (S. pombe)
RBBP6 retinoblastoma binding protein 6
RGS1 regulator of G-protein signaling 1
RHEB Ras homolog enriched in brain
RIOK3 RIO kinase 3
RPL15 ribosomal protein L15
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RSF1 remodeling and spacing factor 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCAF4 SR-related CTD-associated factor 4
SEC23B Sec23 homolog B (S. cerevisiae)
SEC24D SEC24 family member D
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SMG5 SMG5 nonsense mediated mRNA decay factor
SNX11 sorting nexin 11
SPN sialophorin
SRSF11 serine/arginine-rich splicing factor 11
STK19 serine/threonine kinase 19
SUB1 SUB1 homolog (S. cerevisiae)
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TANK TRAF family member-associated NFKB activator
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMED7 transmembrane emp24 protein transport domain containing 7
TSPAN31 tetraspanin 31
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae)
UBA2 ubiquitin-like modifier activating enzyme 2
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE3A ubiquitin protein ligase E3A
USF2 upstream transcription factor 2, c-fos interacting
WIZ widely interspaced zinc finger motifs
YIPF4 Yip1 domain family, member 4
ZEB2 zinc finger E-box binding homeobox 2
ZMYM2 zinc finger, MYM-type 2
ZNF280D zinc finger protein 280D
ZNF426 zinc finger protein 426
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACOT13 acyl-CoA thioesterase 13
ACOT8 acyl-CoA thioesterase 8
ADAT1 adenosine deaminase, tRNA-specific 1
ADTRP androgen-dependent TFPI-regulating protein
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APOD apolipoprotein D
ARHGAP10 Rho GTPase activating protein 10
ATAT1 alpha tubulin acetyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
C8ORF60 chromosome 8 open reading frame 60
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC176 coiled-coil domain containing 176
CD151 CD151 molecule (Raph blood group)
CD82 CD82 molecule
CEP70 centrosomal protein 70kDa
CER1 cerberus 1, DAN family BMP antagonist
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN11 claudin 11
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
CNR2 cannabinoid receptor 2 (macrophage)
CNTD2 cyclin N-terminal domain containing 2
CNTNAP1 contactin associated protein 1
CPA4 carboxypeptidase A4
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DOK2 docking protein 2, 56kDa
DPF3 D4, zinc and double PHD fingers, family 3
EDAR ectodysplasin A receptor
ERCC8 excision repair cross-complementation group 8
FBXL6 F-box and leucine-rich repeat protein 6
FHOD1 formin homology 2 domain containing 1
FMO4 flavin containing monooxygenase 4
GAA glucosidase, alpha; acid
GBAP1 glucosidase, beta, acid pseudogene 1
GLB1L2 galactosidase, beta 1-like 2
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPR27 G protein-coupled receptor 27
GTPBP2 GTP binding protein 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFITM3 interferon induced transmembrane protein 3
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
INO80D INO80 complex subunit D
ITPKC inositol-trisphosphate 3-kinase C
JMJD4 jumonji domain containing 4
KIAA0355 KIAA0355
KIF5A kinesin family member 5A
KLK1 kallikrein 1
LMBR1L limb development membrane protein 1-like
MAGEF1 melanoma antigen family F1
MBOAT2 membrane bound O-acyltransferase domain containing 2
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MFSD11 major facilitator superfamily domain containing 11
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCKAP1L NCK-associated protein 1-like
NHEJ1 nonhomologous end-joining factor 1
NUBP2 nucleotide binding protein 2
NXPH3 neurexophilin 3
OVGP1 oviductal glycoprotein 1, 120kDa
PADI1 peptidyl arginine deiminase, type I
PCDHGB5 protocadherin gamma subfamily B, 5
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
QPRT quinolinate phosphoribosyltransferase
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SDF2L1 stromal cell-derived factor 2-like 1
SH3GL1 SH3-domain GRB2-like 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLN sarcolipin
SNTA1 syntrophin, alpha 1
SREBF1 sterol regulatory element binding transcription factor 1
STAC SH3 and cysteine rich domain
STARD3 StAR-related lipid transfer (START) domain containing 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAC3 tachykinin 3
TGFB3 transforming growth factor, beta 3
TMPRSS6 transmembrane protease, serine 6
TRIM26 tripartite motif containing 26
TRIM66 tripartite motif containing 66
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSPAN32 tetraspanin 32
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae)
TXLNA taxilin alpha
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC45A unc-45 homolog A (C. elegans)
UPF2 UPF2 regulator of nonsense transcripts homolog (yeast)
WFS1 Wolfram syndrome 1 (wolframin)
YIPF1 Yip1 domain family, member 1
ZBED1 zinc finger, BED-type containing 1
ZNF408 zinc finger protein 408
ZNHIT2 zinc finger, HIT-type containing 2