atracurium besilate-7477 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the atracurium besilate-7477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADARB1 adenosine deaminase, RNA-specific, B1
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALPK1 alpha-kinase 1
AQP3 aquaporin 3 (Gill blood group)
ATP10A ATPase, class V, type 10A
ATP9A ATPase, class II, type 9A
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C5ORF45 chromosome 5 open reading frame 45
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPG capping protein (actin filament), gelsolin-like
CAPN9 calpain 9
CCDC71 coiled-coil domain containing 71
CCDC93 coiled-coil domain containing 93
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHKB choline kinase beta
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLDN17 claudin 17
CLTA clathrin, light chain A
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa
CREM cAMP responsive element modulator
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DESI2 desumoylating isopeptidase 2
DICER1 dicer 1, ribonuclease type III
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DNM1 dynamin 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHBP1L1 EH domain binding protein 1-like 1
ENGASE endo-beta-N-acetylglucosaminidase
EPHB3 EPH receptor B3
ERCC2 excision repair cross-complementation group 2
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM134B family with sequence similarity 134, member B
FAM65A family with sequence similarity 65, member A
FANCA Fanconi anemia, complementation group A
FAS Fas cell surface death receptor
FGF12 fibroblast growth factor 12
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLS2 glutaminase 2 (liver, mitochondrial)
GNAS GNAS complex locus
GRSF1 G-rich RNA sequence binding factor 1
GYPB glycophorin B (MNS blood group)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HMOX1 heme oxygenase 1
ICA1 islet cell autoantigen 1, 69kDa
IFITM1 interferon induced transmembrane protein 1
IPO9 importin 9
KIAA0485 uncharacterized LOC57235
KIAA0930 KIAA0930
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAST3 microtubule associated serine/threonine kinase 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED6 mediator complex subunit 6
MFAP3L microfibrillar-associated protein 3-like
MINK1 misshapen-like kinase 1
NCAPH2 non-SMC condensin II complex, subunit H2
NDE1 nudE neurodevelopment protein 1
OASL 2'-5'-oligoadenylate synthetase-like
OSGIN1 oxidative stress induced growth inhibitor 1
PASK PAS domain containing serine/threonine kinase
PILRA paired immunoglobin-like type 2 receptor alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLXNB1 plexin B1
PMEL premelanosome protein
RASAL1 RAS protein activator like 1 (GAP1 like)
RNFT2 ring finger protein, transmembrane 2
S100A4 S100 calcium binding protein A4
S100A6 S100 calcium binding protein A6
SARM1 sterile alpha and TIR motif containing 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2D3A SH2 domain containing 3A
SH2D4A SH2 domain containing 4A
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TESK1 testis-specific kinase 1
THBD thrombomodulin
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TREX1 three prime repair exonuclease 1
TTC9 tetratricopeptide repeat domain 9
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
ZBTB17 zinc finger and BTB domain containing 17
ZNF205 zinc finger protein 205
ZNF767P zinc finger family member 767, pseudogene
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ANKRD36 ankyrin repeat domain 36
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATP7B ATPase, Cu++ transporting, beta polypeptide
BAGE B melanoma antigen
BPGM 2,3-bisphosphoglycerate mutase
BSPRY B-box and SPRY domain containing
C11ORF30 chromosome 11 open reading frame 30
CA11 carbonic anhydrase XI
CCDC25 coiled-coil domain containing 25
CCDC85C coiled-coil domain containing 85C
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDK3 cyclin-dependent kinase 3
CGREF1 cell growth regulator with EF-hand domain 1
CHML choroideremia-like (Rab escort protein 2)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DSCAM Down syndrome cell adhesion molecule
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
EPHA2 EPH receptor A2
ERCC5 excision repair cross-complementation group 5
ERO1L ERO1-like (S. cerevisiae)
FAM111A family with sequence similarity 111, member A
FBXO31 F-box protein 31
HCFC2 host cell factor C2
HIST1H4F histone cluster 1, H4f
HPN hepsin
HS1BP3 HCLS1 binding protein 3
IL17RA interleukin 17 receptor A
INADL InaD-like (Drosophila)
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
KDM7A lysine (K)-specific demethylase 7A
KLHDC4 kelch domain containing 4
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LNPEP leucyl/cystinyl aminopeptidase
LRP3 low density lipoprotein receptor-related protein 3
LTBP2 latent transforming growth factor beta binding protein 2
LYPD1 LY6/PLAUR domain containing 1
LZTFL1 leucine zipper transcription factor-like 1
MAGEH1 melanoma antigen family H1
MAP1S microtubule-associated protein 1S
MCOLN3 mucolipin 3
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
MYO1F myosin IF
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NDRG4 NDRG family member 4
NES nestin
NKAIN1 Na+/K+ transporting ATPase interacting 1
NPIPB15 nuclear pore complex interacting protein family, member B15
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
NT5DC3 5'-nucleotidase domain containing 3
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
PADI2 peptidyl arginine deiminase, type II
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PAIP2B poly(A) binding protein interacting protein 2B
PEX26 peroxisomal biogenesis factor 26
PGP phosphoglycolate phosphatase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRICKLE3 prickle homolog 3 (Drosophila)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
REPS2 RALBP1 associated Eps domain containing 2
RFTN1 raftlin, lipid raft linker 1
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RWDD2A RWD domain containing 2A
SGMS1 sphingomyelin synthase 1
SIDT1 SID1 transmembrane family, member 1
SLC46A3 solute carrier family 46, member 3
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
STAG3 stromal antigen 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
STK25 serine/threonine kinase 25
SUSD6 sushi domain containing 6
TMPRSS4 transmembrane protease, serine 4
TMSB15A thymosin beta 15a
TRAF2 TNF receptor-associated factor 2
TTC33 tetratricopeptide repeat domain 33
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VEGFC vascular endothelial growth factor C
VGF VGF nerve growth factor inducible
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMYM1 zinc finger, MYM-type 1
ZNF408 zinc finger protein 408