atracurium besilate-1824 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the atracurium besilate-1824 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACAA2 acetyl-CoA acyltransferase 2
ACVR1 activin A receptor, type I
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ARF6 ADP-ribosylation factor 6
ARHGAP26 Rho GTPase activating protein 26
ARMT1 acidic residue methyltransferase 1
ARTN artemin
ASB1 ankyrin repeat and SOCS box containing 1
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BBS4 Bardet-Biedl syndrome 4
BCL6 B-cell CLL/lymphoma 6
BMP2 bone morphogenetic protein 2
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C10ORF10 chromosome 10 open reading frame 10
CAPN10 calpain 10
CCPG1 cell cycle progression 1
CDC37L1 cell division cycle 37-like 1
CEP290 centrosomal protein 290kDa
CEP57 centrosomal protein 57kDa
CEP68 centrosomal protein 68kDa
CHAF1A chromatin assembly factor 1, subunit A (p150)
CLCC1 chloride channel CLIC-like 1
CLTB clathrin, light chain B
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
DAZAP2 DAZ associated protein 2
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DUS4L dihydrouridine synthase 4-like (S. cerevisiae)
EIF4E eukaryotic translation initiation factor 4E
ELOVL4 ELOVL fatty acid elongase 4
EVI5 ecotropic viral integration site 5
FAM117A family with sequence similarity 117, member A
FAT4 FAT atypical cadherin 4
FCHSD2 FCH and double SH3 domains 2
FSCN1 fascin actin-bundling protein 1
FSD1 fibronectin type III and SPRY domain containing 1
GPR107 G protein-coupled receptor 107
GRAMD4 GRAM domain containing 4
HCRP1 hepatocellular carcinoma-related HCRP1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HMOX2 heme oxygenase 2
HNMT histamine N-methyltransferase
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IL1RAP interleukin 1 receptor accessory protein
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIAA0319L KIAA0319-like
LRRC40 leucine rich repeat containing 40
LYPD3 LY6/PLAUR domain containing 3
MAP3K4 mitogen-activated protein kinase kinase kinase 4
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MTMR9 myotubularin related protein 9
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NLE1 notchless homolog 1 (Drosophila)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAQR3 progestin and adipoQ receptor family member III
PCDH1 protocadherin 1
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PGAP1 post-GPI attachment to proteins 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLSCR4 phospholipid scramblase 4
RAB27A RAB27A, member RAS oncogene family
RAD23B RAD23 homolog B (S. cerevisiae)
RARS arginyl-tRNA synthetase
RC3H2 ring finger and CCCH-type domains 2
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SLC25A44 solute carrier family 25, member 44
SLC38A6 solute carrier family 38, member 6
SMG7 SMG7 nonsense mediated mRNA decay factor
SOCS6 suppressor of cytokine signaling 6
SRSF10 serine/arginine-rich splicing factor 10
SS18 synovial sarcoma translocation, chromosome 18
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
STK16 serine/threonine kinase 16
SYNGR1 synaptogyrin 1
TADA2A transcriptional adaptor 2A
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBX2 T-box 2
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
THAP1 THAP domain containing, apoptosis associated protein 1
TM2D1 TM2 domain containing 1
TNS2 tensin 2
TPK1 thiamin pyrophosphokinase 1
TRIM2 tripartite motif containing 2
TTC38 tetratricopeptide repeat domain 38
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF205 zinc finger protein 205
ZNF358 zinc finger protein 358
ZNF468 zinc finger protein 468
ZNF592 zinc finger protein 592

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AGBL5 ATP/GTP binding protein-like 5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
AP4M1 adaptor-related protein complex 4, mu 1 subunit
ASAP1-IT1 ASAP1 intronic transcript 1
ASTE1 asteroid homolog 1 (Drosophila)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BDNF brain-derived neurotrophic factor
BIN3 bridging integrator 3
BTBD2 BTB (POZ) domain containing 2
C8ORF60 chromosome 8 open reading frame 60
CCDC176 coiled-coil domain containing 176
CCDC85C coiled-coil domain containing 85C
CCNT1 cyclin T1
CEP97 centrosomal protein 97kDa
CHMP6 charged multivesicular body protein 6
CTGF connective tissue growth factor
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DHRS9 dehydrogenase/reductase (SDR family) member 9
DNASE1L1 deoxyribonuclease I-like 1
DUSP8 dual specificity phosphatase 8
EDC3 enhancer of mRNA decapping 3
EDN1 endothelin 1
EFNA3 ephrin-A3
ELP3 elongator acetyltransferase complex subunit 3
EN2 engrailed homeobox 2
EXOC5 exocyst complex component 5
FAIM Fas apoptotic inhibitory molecule
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP10 FK506 binding protein 10, 65 kDa
GALK1 galactokinase 1
GALT galactose-1-phosphate uridylyltransferase
GLDC glycine dehydrogenase (decarboxylating)
HDAC7 histone deacetylase 7
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
KCTD15 potassium channel tetramerization domain containing 15
KIAA0894 KIAA0894 protein
KIF13B kinesin family member 13B
LIF leukemia inhibitory factor
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEF1 melanoma antigen family F1
MED9 mediator complex subunit 9
MNX1 motor neuron and pancreas homeobox 1
MOGS mannosyl-oligosaccharide glucosidase
MOSPD3 motile sperm domain containing 3
MRPS34 mitochondrial ribosomal protein S34
MYLK myosin light chain kinase
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa
NID2 nidogen 2 (osteonidogen)
NINL ninein-like
NOTCH1 notch 1
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR2C2 nuclear receptor subfamily 2, group C, member 2
ODF2 outer dense fiber of sperm tails 2
PCOLCE procollagen C-endopeptidase enhancer
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCH pro-melanin-concentrating hormone
PSKH1 protein serine kinase H1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PTTG3P pituitary tumor-transforming 3, pseudogene
PYCRL pyrroline-5-carboxylate reductase-like
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RBM42 RNA binding motif protein 42
RNF121 ring finger protein 121
RPS17P5 ribosomal protein S17 pseudogene 5
SIRT2 sirtuin 2
SLC25A22 solute carrier family 25 (mitochondrial carrier: glutamate), member 22
SLC41A3 solute carrier family 41, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNHG20 small nucleolar RNA host gene 20
SOX12 SRY (sex determining region Y)-box 12
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D2 TBC1 domain family, member 2
TINAGL1 tubulointerstitial nephritis antigen-like 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM8B transmembrane protein 8B
TPRA1 transmembrane protein, adipocyte asscociated 1
TTPAL tocopherol (alpha) transfer protein-like
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
URM1 ubiquitin related modifier 1
ZMAT5 zinc finger, matrin-type 5
ZNF571 zinc finger protein 571
ZNF629 zinc finger protein 629
ZNF747 zinc finger protein 747