atracurium besilate-1702 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the atracurium besilate-1702 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARSB arylsulfatase B
ATAD5 ATPase family, AAA domain containing 5
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
BAGE B melanoma antigen
BMP4 bone morphogenetic protein 4
C18ORF25 chromosome 18 open reading frame 25
C3 complement component 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCDC28B coiled-coil domain containing 28B
CCNG2 cyclin G2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COMT catechol-O-methyltransferase
CXCR4 chemokine (C-X-C motif) receptor 4
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLX4 distal-less homeobox 4
DMTN dematin actin binding protein
EGFL7 EGF-like-domain, multiple 7
EIF5 eukaryotic translation initiation factor 5
EMC1 ER membrane protein complex subunit 1
ESR1 estrogen receptor 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAN gigaxonin
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GOLGA8B golgin A8 family, member B
GPR107 G protein-coupled receptor 107
GRM1 glutamate receptor, metabotropic 1
GYG2 glycogenin 2
HIST1H2BG histone cluster 1, H2bg
HK2 hexokinase 2
HMGB3P1 high mobility group box 3 pseudogene 1
HP1BP3 heterochromatin protein 1, binding protein 3
HSF2 heat shock transcription factor 2
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
JUN jun proto-oncogene
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KDM7A lysine (K)-specific demethylase 7A
KMT2A lysine (K)-specific methyltransferase 2A
LAMC2 laminin, gamma 2
LMAN1 lectin, mannose-binding, 1
LONP2 lon peptidase 2, peroxisomal
LPP LIM domain containing preferred translocation partner in lipoma
LRP6 low density lipoprotein receptor-related protein 6
MARCKS myristoylated alanine-rich protein kinase C substrate
MOCS1 molybdenum cofactor synthesis 1
MR1 major histocompatibility complex, class I-related
MTRF1L mitochondrial translational release factor 1-like
NACA2 nascent polypeptide-associated complex alpha subunit 2
NF1 neurofibromin 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
ODF2 outer dense fiber of sperm tails 2
OSGIN1 oxidative stress induced growth inhibitor 1
PAIP2B poly(A) binding protein interacting protein 2B
PBX2 pre-B-cell leukemia homeobox 2
PCDH9 protocadherin 9
PDCD6 programmed cell death 6
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PRR14L proline rich 14-like
PRR5 proline rich 5 (renal)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL35A ribosomal protein L35a
SH2B1 SH2B adaptor protein 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SOCS3 suppressor of cytokine signaling 3
SOWAHC sosondowah ankyrin repeat domain family member C
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRN striatin, calmodulin binding protein
STX16 syntaxin 16
TADA2A transcriptional adaptor 2A
TBC1D19 TBC1 domain family, member 19
TBC1D5 TBC1 domain family, member 5
TBKBP1 TBK1 binding protein 1
TDRKH tudor and KH domain containing
TMOD3 tropomodulin 3 (ubiquitous)
TMPO thymopoietin
TPMT thiopurine S-methyltransferase
TRIB2 tribbles pseudokinase 2
TTC38 tetratricopeptide repeat domain 38
TTC9 tetratricopeptide repeat domain 9
UBOX5 U-box domain containing 5
UST uronyl-2-sulfotransferase
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WFDC2 WAP four-disulfide core domain 2
ZCCHC24 zinc finger, CCHC domain containing 24
ZSCAN12 zinc finger and SCAN domain containing 12

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACYP1 acylphosphatase 1, erythrocyte (common) type
ANKRD36 ankyrin repeat domain 36
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
ASTN2 astrotactin 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BRPF1 bromodomain and PHD finger containing, 1
C11ORF30 chromosome 11 open reading frame 30
C1ORF159 chromosome 1 open reading frame 159
CAPN15 calpain 15
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CHMP6 charged multivesicular body protein 6
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CLSPN claspin
CORT cortistatin
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYBB2P1 crystallin, beta B2 pseudogene 1
CRYL1 crystallin, lambda 1
CSTA cystatin A (stefin A)
CTNNBIP1 catenin, beta interacting protein 1
DVL1 dishevelled segment polarity protein 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
FANCC Fanconi anemia, complementation group C
FBRS fibrosin
FER fer (fps/fes related) tyrosine kinase
FLT4 fms-related tyrosine kinase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GLS2 glutaminase 2 (liver, mitochondrial)
GNPDA1 glucosamine-6-phosphate deaminase 1
GRAMD4 GRAM domain containing 4
HIST1H2AJ histone cluster 1, H2aj
HMHA1 histocompatibility (minor) HA-1
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IFT140 intraflagellar transport 140
IRF9 interferon regulatory factor 9
JADE1 jade family PHD finger 1
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM5C lysine (K)-specific demethylase 5C
KIAA0556 KIAA0556
KRBOX4 KRAB box domain containing 4
LAMA3 laminin, alpha 3
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LINC00339 long intergenic non-protein coding RNA 339
LMBR1L limb development membrane protein 1-like
LRRC14 leucine rich repeat containing 14
LTBP2 latent transforming growth factor beta binding protein 2
LYPD1 LY6/PLAUR domain containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MUM1 melanoma associated antigen (mutated) 1
NOTCH1 notch 1
NPFFR1 neuropeptide FF receptor 1
NRSN2 neurensin 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OLFML2A olfactomedin-like 2A
P3H1 prolyl 3-hydroxylase 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLXNA3 plexin A3
PROCR protein C receptor, endothelial
PTPRU protein tyrosine phosphatase, receptor type, U
PXMP4 peroxisomal membrane protein 4, 24kDa
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNF25 ring finger protein 25
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SALL2 spalt-like transcription factor 2
SH2D4A SH2 domain containing 4A
SHROOM2 shroom family member 2
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SND1-IT1 SND1 intronic transcript 1
SOX12 SRY (sex determining region Y)-box 12
SPIDR scaffolding protein involved in DNA repair
STARD13 StAR-related lipid transfer (START) domain containing 13
STK16 serine/threonine kinase 16
TCTA T-cell leukemia translocation altered
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THRAP3 thyroid hormone receptor associated protein 3
TNS2 tensin 2
TPST2 tyrosylprotein sulfotransferase 2
TRAF2 TNF receptor-associated factor 2
TRIM52 tripartite motif containing 52
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF580 zinc finger protein 580
ZNF586 zinc finger protein 586
ZNF696 zinc finger protein 696