atractyloside-7393 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the atractyloside-7393 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
AMPD3 adenosine monophosphate deaminase 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
ARID3B AT rich interactive domain 3B (BRIGHT-like)
BTF3P12 basic transcription factor 3 pseudogene 12
CA5B carbonic anhydrase VB, mitochondrial
CABP2 calcium binding protein 2
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC25C cell division cycle 25C
CDK10 cyclin-dependent kinase 10
CES1 carboxylesterase 1
CES3 carboxylesterase 3
CHRM3 cholinergic receptor, muscarinic 3
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DCLK2 doublecortin-like kinase 2
DCN decorin
DENND2A DENN/MADD domain containing 2A
DGKE diacylglycerol kinase, epsilon 64kDa
DOCK9 dedicator of cytokinesis 9
DPT dermatopontin
EDA ectodysplasin A
ETV1 ets variant 1
ETV5 ets variant 5
EWSR1 EWS RNA-binding protein 1
FAM186A family with sequence similarity 186, member A
FKBP8 FK506 binding protein 8, 38kDa
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPER1 G protein-coupled estrogen receptor 1
GPR1 G protein-coupled receptor 1
GUK1 guanylate kinase 1
HAUS5 HAUS augmin-like complex, subunit 5
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXB5 homeobox B5
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IL17RA interleukin 17 receptor A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KITLG KIT ligand
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMCD1 LIM and cysteine-rich domains 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MAP3K7CL MAP3K7 C-terminal like
MDFIC MyoD family inhibitor domain containing
METRN meteorin, glial cell differentiation regulator
MRPL57 mitochondrial ribosomal protein L57
MTCP1 mature T-cell proliferation 1
MUC4 mucin 4, cell surface associated
MYLK myosin light chain kinase
MYOZ1 myozenin 1
NAIP NLR family, apoptosis inhibitory protein
NCOA2 nuclear receptor coactivator 2
NPR3 natriuretic peptide receptor 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PCDHB13 protocadherin beta 13
PCM1 pericentriolar material 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFA platelet-derived growth factor alpha polypeptide
PIAS4 protein inhibitor of activated STAT, 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
PPP5C protein phosphatase 5, catalytic subunit
PRDM2 PR domain containing 2, with ZNF domain
RAD52 RAD52 homolog (S. cerevisiae)
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RIBC2 RIB43A domain with coiled-coils 2
RNGTT RNA guanylyltransferase and 5'-phosphatase
SAPCD1 suppressor APC domain containing 1
SCAMP1 secretory carrier membrane protein 1
SETD8 SET domain containing (lysine methyltransferase) 8
SGSM3 small G protein signaling modulator 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC17A2 solute carrier family 17, member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SOD3 superoxide dismutase 3, extracellular
SPTAN1 spectrin, alpha, non-erythrocytic 1
SREBF2 sterol regulatory element binding transcription factor 2
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
THBS3 thrombospondin 3
TLN2 talin 2
TRAPPC13 trafficking protein particle complex 13
TRPC5 transient receptor potential cation channel, subfamily C, member 5
WSB1 WD repeat and SOCS box containing 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YTHDC1 YTH domain containing 1
ZBTB7A zinc finger and BTB domain containing 7A
ZNF141 zinc finger protein 141
ZNF205 zinc finger protein 205
ZNF276 zinc finger protein 276
ZNF408 zinc finger protein 408
ZNF442 zinc finger protein 442
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AFAP1 actin filament associated protein 1
AKAP7 A kinase (PRKA) anchor protein 7
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BRCA2 breast cancer 2, early onset
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAPN15 calpain 15
CASZ1 castor zinc finger 1
CBX7 chromobox homolog 7
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH7 cadherin 7, type 2
CDON cell adhesion associated, oncogene regulated
CFAP44 cilia and flagella associated protein 44
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DUSP10 dual specificity phosphatase 10
ELP3 elongator acetyltransferase complex subunit 3
ELP6 elongator acetyltransferase complex subunit 6
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FA2H fatty acid 2-hydroxylase
FADS2 fatty acid desaturase 2
FOXC1 forkhead box C1
GAB2 GRB2-associated binding protein 2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GTF2I general transcription factor IIi
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUF1 GUF1 GTPase homolog (S. cerevisiae)
HIST1H3C histone cluster 1, H3c
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IFI44L interferon-induced protein 44-like
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IPO8 importin 8
ISL1 ISL LIM homeobox 1
ISYNA1 inositol-3-phosphate synthase 1
ITPKC inositol-trisphosphate 3-kinase C
KIAA1107 KIAA1107
KIF16B kinesin family member 16B
KPNA5 karyopherin alpha 5 (importin alpha 6)
KRT34 keratin 34, type I
LHFPL2 lipoma HMGIC fusion partner-like 2
LIG4 ligase IV, DNA, ATP-dependent
LRP5L low density lipoprotein receptor-related protein 5-like
MAN2C1 mannosidase, alpha, class 2C, member 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MMP1 matrix metallopeptidase 1
MOSPD3 motile sperm domain containing 3
MTHFSD methenyltetrahydrofolate synthetase domain containing
NCS1 neuronal calcium sensor 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NSMF NMDA receptor synaptonuclear signaling and neuronal migration factor
NUBP2 nucleotide binding protein 2
OLFML2A olfactomedin-like 2A
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PARP16 poly (ADP-ribose) polymerase family, member 16
PHC1 polyhomeotic homolog 1 (Drosophila)
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLAC8 placenta-specific 8
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARS arginyl-tRNA synthetase
RBM47 RNA binding motif protein 47
SALL2 spalt-like transcription factor 2
SCN1B sodium channel, voltage gated, type I beta subunit
STAC SH3 and cysteine rich domain
STIM1 stromal interaction molecule 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM53 transmembrane protein 53
TNNI3 troponin I type 3 (cardiac)
TRABD TraB domain containing
TRAPPC11 trafficking protein particle complex 11
TRIM26 tripartite motif containing 26
TTC31 tetratricopeptide repeat domain 31
USP27X ubiquitin specific peptidase 27, X-linked
VEGFB vascular endothelial growth factor B
YOD1 YOD1 deubiquitinase
ZBTB39 zinc finger and BTB domain containing 39
ZNF175 zinc finger protein 175
ZNF189 zinc finger protein 189
ZNF34 zinc finger protein 34
ZNF510 zinc finger protein 510