atractyloside-2573 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the atractyloside-2573 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD8 abhydrolase domain containing 8
ACOX1 acyl-CoA oxidase 1, palmitoyl
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGAP1 Rho GTPase activating protein 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASPH aspartate beta-hydroxylase
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCL2L2 BCL2-like 2
BLVRA biliverdin reductase A
BMP8B bone morphogenetic protein 8b
C1R complement component 1, r subcomponent
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCL20 chemokine (C-C motif) ligand 20
CDKL3 cyclin-dependent kinase-like 3
CHM choroideremia (Rab escort protein 1)
COMMD4 COMM domain containing 4
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPQ carboxypeptidase Q
CRTC1 CREB regulated transcription coactivator 1
CSF2RA colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
CTNNBL1 catenin, beta like 1
DAGLA diacylglycerol lipase, alpha
DCAF13 DDB1 and CUL4 associated factor 13
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DRD2 dopamine receptor D2
DUSP4 dual specificity phosphatase 4
E2F5 E2F transcription factor 5, p130-binding
EDRF1 erythroid differentiation regulatory factor 1
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FAM153A family with sequence similarity 153, member A
FCAR Fc fragment of IgA receptor
FUS FUS RNA binding protein
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GAN gigaxonin
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPR153 G protein-coupled receptor 153
GPR22 G protein-coupled receptor 22
GRIP2 glutamate receptor interacting protein 2
GSN gelsolin
HIPK3 homeodomain interacting protein kinase 3
HIST1H4A histone cluster 1, H4a
INPP5K inositol polyphosphate-5-phosphatase K
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KHSRP KH-type splicing regulatory protein
KLF3 Kruppel-like factor 3 (basic)
LARP7 La ribonucleoprotein domain family, member 7
LAT2 linker for activation of T cells family, member 2
LIG4 ligase IV, DNA, ATP-dependent
LOX lysyl oxidase
LRRK1 leucine-rich repeat kinase 1
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae)
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP4 microtubule-associated protein 4
MDM4 MDM4, p53 regulator
MR1 major histocompatibility complex, class I-related
MTA2 metastasis associated 1 family, member 2
MTAP methylthioadenosine phosphorylase
MYH14 myosin, heavy chain 14, non-muscle
NF2 neurofibromin 2 (merlin)
OCLM oculomedin
PARP3 poly (ADP-ribose) polymerase family, member 3
PHTF2 putative homeodomain transcription factor 2
PLSCR3 phospholipid scramblase 3
POMT2 protein-O-mannosyltransferase 2
PYCRL pyrroline-5-carboxylate reductase-like
RAD51B RAD51 paralog B
RGS10 regulator of G-protein signaling 10
RGS3 regulator of G-protein signaling 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPL13 ribosomal protein L13
RRP1B ribosomal RNA processing 1B
RXRB retinoid X receptor, beta
SAA3P serum amyloid A3 pseudogene
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SMAD5 SMAD family member 5
SP1 Sp1 transcription factor
SPATA6 spermatogenesis associated 6
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBCD tubulin folding cofactor D
TBRG4 transforming growth factor beta regulator 4
TBXA2R thromboxane A2 receptor
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
THPO thrombopoietin
TMEM180 transmembrane protein 180
TOR1AIP1 torsin A interacting protein 1
TSC22D1 TSC22 domain family, member 1
TWF1 twinfilin actin binding protein 1
UMPS uridine monophosphate synthetase
VAMP4 vesicle-associated membrane protein 4
WDR76 WD repeat domain 76
ZNF215 zinc finger protein 215

decreased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRD2 adhesion G protein-coupled receptor D2
AMT aminomethyltransferase
APOC4 apolipoprotein C-IV
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BMP15 bone morphogenetic protein 15
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CCL21 chemokine (C-C motif) ligand 21
CD300C CD300c molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CDHR2 cadherin-related family member 2
CEP97 centrosomal protein 97kDa
CFAP45 cilia and flagella associated protein 45
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLIP2 CAP-GLY domain containing linker protein 2
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CPNE7 copine VII
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPN1 epsin 1
EXOSC1 exosome component 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FGF23 fibroblast growth factor 23
FRMPD1 FERM and PDZ domain containing 1
FZD4 frizzled class receptor 4
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GSN-AS1 GSN antisense RNA 1
HAMP hepcidin antimicrobial peptide
HIST1H1T histone cluster 1, H1t
HIST1H2AJ histone cluster 1, H2aj
HOXB9 homeobox B9
IFNA17 interferon, alpha 17
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGKV3-20 immunoglobulin kappa variable 3-20
IL11RA interleukin 11 receptor, alpha
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INF2 inverted formin, FH2 and WH2 domain containing
INO80D INO80 complex subunit D
KCTD15 potassium channel tetramerization domain containing 15
KIAA0319L KIAA0319-like
LIME1 Lck interacting transmembrane adaptor 1
LIMS2 LIM and senescent cell antigen-like domains 2
LINC00260 long intergenic non-protein coding RNA 260
LOC729164 hCG1732469
LRRC49 leucine rich repeat containing 49
LRRC6 leucine rich repeat containing 6
LY6D lymphocyte antigen 6 complex, locus D
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCS1 neuronal calcium sensor 1
NT5DC3 5'-nucleotidase domain containing 3
OLFM4 olfactomedin 4
PAIP2B poly(A) binding protein interacting protein 2B
PCBP4 poly(rC) binding protein 4
PCDH12 protocadherin 12
PDE8B phosphodiesterase 8B
PER3 period circadian clock 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PLAT plasminogen activator, tissue
PMEL premelanosome protein
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRO2964 uncharacterized protein PRO2964
PRR7 proline rich 7 (synaptic)
RAB40A RAB40A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SH2D3C SH2 domain containing 3C
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC12A8 solute carrier family 12, member 8
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOX12 SRY (sex determining region Y)-box 12
SPEF1 sperm flagellar 1
STX11 syntaxin 11
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAS2R1 taste receptor, type 2, member 1
TAS2R10 taste receptor, type 2, member 10
TBX19 T-box 19
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TRAF2 TNF receptor-associated factor 2
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
ZNF280A zinc finger protein 280A
ZNF710 zinc finger protein 710
ZNF76 zinc finger protein 76